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J Ethnopharmacol ; 155(3): 1441-9, 2014 Sep 29.
Artigo em Inglês | MEDLINE | ID: mdl-25046828

RESUMO

ETHNOPHARMACOLOGICAL RELEVANCE: Ethnopharmacological surveys show that several plant species are used empirically by the population, in oral diseases. However, it is necessary to check the properties of these plant species. AIM OF THE STUDY: To evaluate in vitro antimicrobial activity against Streptococcus mutans from plant species selected in a previous ethnopharmacology study. MATERIALS AND METHODS: An ethnopharmacological survey was conducted with users of a dental clinic school services, located in Sao Luis, Maranhão, Brazil, aiming to identify plant species used in oral diseases treatment. From the ethnopharmacological survey, species were selected for in vitro antimicrobial activity evaluation against Streptococcus mutans, by agar diffusion method and determination of Minimum Inhibitory Concentration (MIC). RESULTS: Two hundred and seventy one people participated in the research: 55.7% reported the use of plants for medicinal purposes, 29.5% of which have knowledge and/or use plants for some type of oral disease. Thirty four species belonging to 24 (twenty four) botanical families were reported, being Aloe vera L., Anacardium occidentale L., Schinus terebinthifolius Raddi, Chenopodium ambrosioides L. and Punica granatum L. the most cited. The most commonly reported indications were healing after tooth extraction, followed by toothache, inflammation and bleeding gums., The determination of Minimum Inhibitory Concentration (MIC) demonstrated that Punica granatum L., Psidium guajava L. and Schinus terebinthifolius Raddi showed similar activity to 0.12% chlorhexidine, used as positive control. CONCLUSION: That result is important to follow up the study of these species in the search for new anticariogenic agents originated by plants.


Assuntos
Anti-Infecciosos/farmacologia , Extratos Vegetais/farmacologia , Plantas Medicinais , Doenças Estomatognáticas/tratamento farmacológico , Streptococcus mutans/efeitos dos fármacos , Adolescente , Adulto , Anti-Infecciosos/uso terapêutico , Brasil , Etnofarmacologia , Feminino , Humanos , Masculino , Testes de Sensibilidade Microbiana , Pessoa de Meia-Idade , Fitoterapia , Extratos Vegetais/uso terapêutico , Streptococcus mutans/crescimento & desenvolvimento , Adulto Jovem
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