Influencia de las intervenciones realizadas durante el parto en la duración de la lactancia materna / Influence of the interventions during labour on breastfeeding duration

Objetivo: Analizar la influencia de diferentes intervenciones clínicas realizadas durante el parto sobre el inicio y mantenimiento de la lactancia materna (LM) a los 4, 6 y 12 meses. Método: Estudio observacional prospectivo. Se llevó a cabo en el Hospital do Salnés de Vilagarcía de Arousa (Pontevedra). La población de estudio fueron mujeres que dieron a luz entre marzo y diciembre de 2016 con intención de amamantar. Se realizó seguimiento de la muestra durante 12 meses o hasta abandonar la LM. La variable de resultado fue la duración total de la LM. Las variables independientes fueron una serie de intervenciones frecuentes en el proceso perinatal. También se analizó el efecto acumulativo negativo de dichas intervenciones sobre la LM. Resultados: Se obtuvo una muestra de 189 mujeres. El tiempo de LM mediano fue de 12 meses en el grupo sin intervenciones, de 10 meses en el grupo de 1-3 intervenciones y de 5 en el grupo de 4 o más intervenciones, siendo las diferencias estadísticamente significativas (p= 0,014). Los eventuales factores de confusión o ajuste se estudiaron mediante análisis multivariante. Cabe destacar el efecto positivo de no utilizar la epidural para conseguir una LM que se mantenga hasta los 12 meses ( odds ratio 2,1; p= 0,03). Conclusiones: Es necesario un mayor esfuerzo por parte de las instituciones para capacitar y sensibilizar al personal sanitario en cuanto a las normas y prácticas relacionadas con la atención amigable a la madre, así como dar a conocer el efecto acumulativo negativo de las intervenciones realizadas en el parto. Las mujeres que necesiten múltiples intervenciones durante el parto podrían precisar ayuda suplementaria para mejorar sus resultados en la LM

Objective: To evaluate the influence of different clinical procedures (operations) during labour on the beginning and maintenance of breastfeeding at 4, 6 and 12 months. Method: An observational-prospective study was carried out at the Salnés Hospital (Vilagarcía de Arousa, Pontevedra). The study population were women who had given birth between March and December 2016 and had the intention of breastfeeding their babies. The sample of 189 women were followed for 12 months or until breastfeeding was ceased. The result variable was the total length of breastfeeding. Independent variables were a series of frequent procedures during labour. The negative accumulative effect on breastfeeding was also analysed. Results: The average breastfeeding time was 12 months in the group undergoing no procedures, 10 months in the group undergoing 1-3 procedures and 5 months in the group undergoing 4 or more procedures. The statistical differences are significant (p= 0.014). The potential confusion or adjustment factors were analysed by means of multivariate analysis. It is worth highlighting the positive effect of not using the epidural to achieve an LM that is maintained until 12 months (odds ratio 2.1; p= 0.03). Conclusions: A greater effort is necessary on behalf of the institutions to not only train and sensitize their staff about the guidelines and practice related to offering kind care to the mother, but also making them aware of the negative accumulative effect of the procedures carried out during labour. Women who undergo several procedures during labour may need extra support in order to improve their breastfeeding results

13C-mixed triglyceride breath test to assess oral enzyme substitution therapy in patients with chronic pancreatitis.

BACKGROUND & AIMS: Malnutrition persists in most patients with chronic pancreatitis despite an adequate clinical response to oral pancreatic enzyme substitution therapy. Our aims were to analyze the accuracy of the 13C-mixed triglyceride breath test as a tool for evaluating the effect of enzyme therapy on fat digestion in chronic pancreatitis, and to analyze the impact of modifying the therapy according to the breath test on patients' nutritional status. METHODS: The accuracy of the breath test for monitoring the effect of therapy was evaluated prospectively in 29 patients with maldigestion secondary to chronic pancreatitis by using the coefficient of fat absorption as the gold standard. Therapy was modified to obtain a normal breath test result in a further 20 chronic pancreatitis patients with malnutrition despite an adequate clinical response to the enzyme therapy; the impact of this therapeutic modification on patients' nutritional status was evaluated. RESULTS: The coefficient of fat absorption and breath test results were similar when assessing fat absorption before and during treatment. Modification of the enzyme therapy to normalize fat absorption as assessed by the breath test in the second group of 20 patients was associated with a significant increase of body weight (P < .001), and serum concentrations of retinol binding protein (P < .001) and prealbumin (P < .001). CONCLUSIONS: The 13C-mixed triglyceride breath test is an accurate method to evaluate the effect of enzyme therapy on fat digestion. This method is simpler than the standard fecal fat test to assess therapy in patients with pancreatic exocrine insufficiency. Normalizing fat absorption improves nutrition in these patients.