Perfil de ingreso de los estudiantes de la Licenciatura en Enfermería en una Institución de Educación Superior / Entry profile of students of the Nursing Degree in a Higher Education Institution

Resumen

Introducción: en la medida en que el sistema de educación superior logre tener mayor información sobre el perfil de los estudiantes, autoridades y profesores estarán en mejores condiciones de cumplir con los objetivos esenciales de la educación.

Objetivo: describir y analizar las características de los estudiantes que ingresan a la Licenciatura en Enfermería en una institución de educación superior.

Metodología: estudio transversal analítico, con 469 alumnos de dos generaciones, previo consentimiento informado se aplicó un cuestionario sobre las características personales, familiares, socioeconómicas y escolares. El análisis fue con el programa estadístico SPSS versión 21, Chi cuadrada y t de student.

Resultados: se encontró asociación entre el sentirse a gusto con la Licenciatura en Enfermería y la elección de la carrera p = 0.000; así como con el deseo de cambiarse de carrera p = 0.000 y con el deseo de estudiar un posgrado en Enfermería p = 0.014. No existe relación entre el promedio del bachillerato y el sexo de los alumnos p = 0.108, con el deseo del alumno para realizar estudios de posgrado p = 0.032, con el espacio para el estudio en casa p = 0.064, ni con el acceso a Internet p = 0.822.

Conclusiones: los factores que facilitan u obstaculizan al estudiante en su tránsito por la licenciatura son: el promedio de bachillerato, las horas de estudio y el gusto por la carrera; así como: el nivel socioeconómico bajo y el grado académico y ocupación de los padres.

Abstract

Introduction: To the extent that the higher education system achieves greater information on the profile of students, authorities and teachers will be better able to meet the essential objectives of education.

Objective: Describe and analyze the characteristics of the students that enter the Nursing Degree in a Higher Education Institution.

Methods: Cross-sectional analytical study, with 469 students from two generations, with prior informed consent, a questionnaire was applied on personal, family, socioeconomic and school characteristics. The analysis was with the SPSS version 21, Chi squared test and Student t test.

Results: An association was found between feeling comfortable with the nursing degree and the choice of career p = 0.000; as well as, with the desire to change career p = 0.000 and with the desire to study a postgraduate nursing degree p = 0.014. There is no relationship between the average of the baccalaureate and the sex of the students p = 0.108; with the desire of the student to carry out postgraduate studies p = 0.032; with the space for home study p = 0.064; and with the Internet access p = 0.822.

Conclusions: The factors that facilitate or hinder the student in their transition through the bachelor's degree are: the high school average, the hours of study and the taste for the career; as well as, the low socioeconomic level and the academic degree and occupation of the parents.

Apoptosis and redistribution of the Ro autoantigen in Balb/c mouse like in subacute cutaneous lupus erythematosus.

In subacute cutaneous lupus eryhematosus (SCLE) the cutaneous antigens constitute the main source of Ro and La autoantigens. The aim of this investigation was to demonstrate if UV light increases the availability of Ro autoantigen in the skin, also the blocking effect of Ac-DEVD-CMK a caspase inhibitor was assessed. For this purpose newborn Balb/c mice were UVB irradiated (5-30 mJ/cm(2)) equivalent to a moderate to severe sunburn. Animals were injected with monoclonal anti-Ro antibodies from SCLE patients. Apoptosis was also induced by anti-Fas antibody injection. Skin samples were examined by direct immunofluoresence, by TUNEL, and the expression of caspase 3 by RT-PCR. Major findings of present studies were: 1. UVB irradiation and anti-Fas induced apoptosis of keratinocytes. 2. Apoptosis redistribute the Ro antigen on cell surface and is better triggered by Ro antibody. 3. The caspase 3 inhibitor Ac-DEVD-CMK decreases the availability of Ro autoantigen in epidermis and prevents deposition of anti-Ro. In conclusion, the caspase pathway would be blocked to avoid anti-Ro deposition along skin; this finding would be a prospect in the treatment of SCLE patients.

Characterization of biodegradable films obtained from cysteine-mediated polymerized gliadins.

This study focuses on the effect exerted by interchain disulfide bonds on the functional properties of films made from gliadins when cross-linked with cysteine. Gliadins were extracted from commercial wheat gluten with 70% aqueous ethanol, and cysteine was added to the film-forming solution to promote cross-linking between protein chains. The formation of interchain disulfide bonds was assessed by SDS-PAGE analysis. Gliadin films treated with cysteine maintain their integrity in water and become less extensible while their tensile strength increases as a consequence of the development of a more rigid network. The glass transition temperature of cross-linked films shifts to slightly higher values. The plasticizing effects of glycerol and moisture are also demonstrated. The mechanical behavior of cysteine-cross-linked gliadin films was compared to that of polymeric glutenins. Cross-linked gliadins displayed tensile strength values similar to those of glutenin films but achieved slightly lower elongation values. Cysteine-cross-linked gliadin films present the advantage that they are ethanol soluble, facilitating film fabrication or their application as a coating for food or for any other film or surface.

Anti-idiotype antibodies abrogate the tissue deposition of anti-RNP human autoantibodies injected into neonatal BALB/c mice.

OBJECTIVE: The goals of the current work are: 1) to examine the epidermal deposition of anti-RNP IgG human autoantibodies in neonatal BALB/c mice; 2) to look for immunoregulatory effects of anti-idiotypes allowing one to inhibit the epidermal deposition of anti-RNP antibodies; and 3) to elicit antinuclear antibodies in adult BALB/c mice by internal images of anti-idiotypes. MATERIALS AND METHODS: Anti-idiotype antibodies were produced with human anti-RNP IgG obtained by ion exchange chromatography; F(ab')2 fragments were recovered from pepsin digestion and were purified using Sephacryl S-300. F(ab')2 fragments were then used to immunize New Zealand rabbits. RESULTS: The anti-RNP IgG recognized the 70 kDa protein and the A (31 kDa) and C (19 kDa) proteins, while the anti-idiotype antibody specifically recognized the light or heavy chain of the anti-RNP (Fab')2 fragments. Additionally, anti-idiotypes recognized the anti-RNP IgG from some sera, but not the IgG from other specificities or from normal IgG. When anti-RNP IgG was injected intraperitoneally into BALB/c mice it induced immune complex deposition in the epidermis and at the dermal-epidermal junction. Previous injection of anti-idiotype antibodies abrogated the anti-RNP IgG deposits. Vaccination with anti-idiotypes elicit antinuclear antibodies in adult BALB/c mice. CONCLUSIONS: Anti-idiotype antibodies abrogate in vitro the antinuclear antibody deposition in neonatal BALB/c mice. Anti-idiotype antibodies elicit antinuclear antibodies in adult BALB/c mice.