RESUMO
The infective factor seems to be very important in the physiopathology of intestinal ischaemia syndrome, as we suggested in previous research works, and is probably responsible for the disturbances observed in pulmonary surfactant. In the present research project, 48 mongrel dogs were studied under different situations of experimental intestinal ischaemia (arterial, venous and revascularization) after laparotomy and the pulmonary surfactant was determined in all cases. We conclude that the observed changes in phospholipids (phosphatidylglycerol and phosphatidylinositol particularly) can be directly related to the infective factor and important enough to induce physicochemical alterations of the surfactant and subsequently pulmonary function.
Assuntos
Intestinos/irrigação sanguínea , Isquemia/fisiopatologia , Surfactantes Pulmonares/metabolismo , Animais , Cães , Oclusão Vascular Mesentérica/fisiopatologia , Fosfatidilgliceróis/metabolismo , Fosfatidilinositóis/metabolismo , Fatores de TempoAssuntos
Ducto Colédoco/parasitologia , Fasciola hepatica/isolamento & purificação , Ducto Hepático Comum/parasitologia , Adulto , Doenças dos Ductos Biliares/parasitologia , Colelitíase/etiologia , Doenças do Ducto Colédoco/parasitologia , Fasciolíase/complicações , Fasciolíase/parasitologia , Feminino , HumanosAssuntos
Heparina/uso terapêutico , Tromboflebite/tratamento farmacológico , Adulto , Idoso , Testes de Coagulação Sanguínea , Feminino , Heparina/administração & dosagem , Humanos , Infusões Parenterais , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Tempo de Trombina , Tromboflebite/fisiopatologiaRESUMO
Within the genus Nocardia three species are at present considered to have human pathologic interest: N. asteroides, N. brasiliensis, and N. caviae. These species are usually the etiologic agents of at least two clinical pictures: nocardiosis and actinomycetoma. A case of pulmonar nocardiosis in a 62-year-old male is reported. The patient had asthmatic episodes and on several occasions received treatment with corticoids. The clinical picture basically consisted of an impairment of the general condition with respiratory symptomatology and fever of 38 to 39 degrees C. An opaque pleuropulmonary image was observed on the chest X-ray film, and the diagnosis of tuberculosis was initially established. The correct diagnosis was confirmed through the bacteriological examination of the transtracheal aspirate with the isolation of N. asteroides. Treatment with streptomycin, sulfamethoxazole and trimethoprim achieved the clinical and roentgenologic cure of the patient. After 2 months of treatment the clinical manifestations had disappeared and after 5 months the chest X-ray was normal. Some epidemiologic data are reviewed.
