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1.
Ukr Biokhim Zh (1978) ; 64(4): 94-7, 1992.
Artigo em Russo | MEDLINE | ID: mdl-1280379

RESUMO

Three peptides located in the N-terminal region of the potato virus X coat protein were synthesized by hand solid phase method for epitope mapping of this protein. One of these peptides (nanopeptide) interacted with monoclonal antibodies to native virus X. On the basis of these studies it was assumed, that amino acid sequence of the potato virus X coat protein, which included lysine residue in position 19, is located on the virion surface.


Assuntos
Capsídeo/imunologia , Epitopos/análise , Peptídeos/análise , Vírus de Plantas/química , Sequência de Aminoácidos , Imunofluorescência , Dados de Sequência Molecular , Vírus de Plantas/imunologia
2.
Zh Mikrobiol Epidemiol Immunobiol ; (10): 67-9, 1984 Oct.
Artigo em Russo | MEDLINE | ID: mdl-6524165

RESUMO

Typhoid infection was reproduced by introducing the infective agent into the bone marrow of noninbred rabbits. After the injection of thymostimulin on the first day of infection the release of typhoid bacilli continued for 1-3 weeks; when thymostimulin was injected on day 20, the release of typhoid bacilli stopped in two weeks. In the control group the release of typhoid bacilli continued during the whole term of observation. The injection of thymostimulin at an early period after infection was thus found to prevent the development of chronic typhoid infection with the elimination of the infective agent from the body of rabbits.


Assuntos
Adjuvantes Imunológicos/uso terapêutico , Extratos do Timo/uso terapêutico , Febre Tifoide/prevenção & controle , Animais , Doença Crônica , Avaliação Pré-Clínica de Medicamentos , Imunidade Celular/efeitos dos fármacos , Coelhos , Fatores de Tempo , Febre Tifoide/imunologia
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