Health risk assessment of some selected heavy metals in infant food sold in Wa, Ghana.

Infants remain a high-risk group as far as exposure to toxic metals is concerned. The levels of lead (Pb), cadmium (Cd), nickel (Ni), chromium (Cr), antimony (Sb), mercury (Hg), and arsenic (As) in twenty-two (22) samples of baby foods and formulas were determined using inductively coupled plasma mass spectrometry. The concentrations in (mg/kg) of As, Cd, Cr, Hg, Mn, Ni, Pb, and Sb were in the ranges 0.006-0.057, 0.043-0.064, 0.113-0.33, 0.000-0.002, 1.720-3.568, 0.065-0.183, 0.061-0.368 and 0.017-0.1 respectively. Health risk assessment indices like the Estimated Daily Intake (EDI), Target Hazard Quotient (THQ), Cancer Risk (CR) and Hazard Index (HI) were calculated. EDI values of Hg, Cr, and As were below their recommended tolerable daily intake, that of Ni and Mn were lower in 95% of samples, and Cd was also lower in 50% of the samples. THQ values for As, Cd, Cr, Hg, Mn, Ni, and Pb were 0.32-3.21, 0.75-1.10, 0.65-1.94, 0.00-0.37, 0.21-0.44, 0.08-0.12 and 0.26-1.13 respectively. The CR values were greater than 10-6, making them unacceptable for human consumption. HI values were between 2.68 and 6.83 (greater than 1), which implied that these metals are likely to pose non-carcinogenic health risks to infants.

Formaldehyde Exposure and Its Potential Health Risk in Some Beauty Salons in Kumasi Metropolis.

Cosmetologists may be potentially exposed to high levels of formaldehyde as a result of their exposure to formaldehyde released from the various cosmetic products used in the beauty salons. In order to assess the exposure of cosmetologists to formaldehyde, the indoor air in sixty beauty salons across the ten submetros in Kumasi were sampled to determine the formaldehyde levels and the associated noncarcinogenic human health risks. Sampling was done using System Service Innovation Incorporation air sampler model 1000i, and the MBTH spectrophotometric method was used for analysis. The mean levels of formaldehyde concentrations ranged from 88.67 to 170.67 µg/m3. Out of the sixty salons sampled, 36 salons had formaldehyde levels above the WHO permissible limit of 100 µg/m3 for an eight-hour working period and also exceeded the 55 and 9 µg/m3 for chronic and acute reference exposure limit, respectively, set by the Office of Environmental Health Hazard Assessment. The results of this study revealed that the number of customers that visit the salon in a week, number of salon services offered, and age of salon had a positive significant correlation with the level of formaldehyde determined in each salon. The health risk study also revealed that about 50% of the salons had hazard quotient (HQ) above the safety limit (HQ = 1) and may, therefore, pose health risks to cosmetologists in these salons. Results from the analysis of the questionnaire revealed that hairdressers in salons that provide the entire range of salon services captured in the study are at higher risk to the effects of formaldehyde.

Risk Assessment of Kumasi Metropolis Population in Ghana through Consumption of Fish Contaminated with Formaldehyde.

This study evaluates the exposure of the Ghanaian population of the Kumasi Metropolis of Ghana to formaldehyde through the consumption of fish using 3-Methyl-2-Benzothiazoline Hydrazone method, with trichloroacetic acid as an extracting agent. A total of sixty (60) fish species comprising both local and imported fish were bought from cold stores and fish ponds were analysed. Formaldehyde was found in all the species analysed with concentration ranging from 0.174 to 3.710 µgg-1. However, the levels were still lower than 5 mg/kg, which is the maximum limit established by the Malaysian Food Act and Regulation for formaldehyde in fish. The estimated daily intake values for formaldehyde in the fish species analysed ranged between 4.233 × 10-4 and 3.661 × 10-3 mg/kg BW/day and this was less than the acceptable daily intake of 0.15 and 0.2 mg/kg BW/day suggested by World Health Organization and the United States Environmental Protection Agency for formaldehyde intake, respectively. The results for the hazard quotient calculated for all the species were less than one suggesting that the amount of formaldehyde in the fish is not likely to pose any potential adverse health effects to consumers. Thus, wet fish from Kumasi may be considered safe for consumption because of low formaldehyde content.

Mercury and hydroquinone content of skin toning creams and cosmetic soaps, and the potential risks to the health of Ghanaian women.

In this study, sixty-two (62) skin-lightening creams and soaps were analysed for total mercury and hydroquinone levels. Total mercury was determined by the Cold Vapour Atomic Absorption Spectrophotometry using an automatic mercury analyser and hydroquinone by High Performance Liquid Chromatography. The mean concentration of total mercury in skin toning creams and cosmetic soaps were 0.098 ± 0.082 and 0.152 ± 0.126 µg/g, respectively. The mean concentration of hydroquinone was 0.243 ± 0.385 and 0.035 ± 0.021 % in skin toning creams and cosmetic soaps, respectively. All the creams and soaps analysed had mercury and hydroquinone levels below the US Food and Drug Administration's acceptable limit of 1 µg/g and 2 %, respectively. The low levels of mercury and hydroquinone in the creams and soaps analysed in this study therefore do not pose any potential risk to consumers who are mostly women in Ghana.

Total mercury distribution in different tissues of six species of freshwater fish from the Kpong hydroelectric reservoir in Ghana.

Total mercury concentrations were determined in seven tissues of 38 fish samples comprising six species from the Kpong hydroelectric reservoir in Ghana by cold vapour atomic absorption spectrometry technique using an automatic mercury analyzer. Mercury concentration in all the tissues ranged from 0.005 to 0.022 µg/g wet weight. In general, the concentration of mercury in all the tissues were decreasing in the order; liver > muscle > intestine > stomach > gonad > gill > swim bladder. Mercury concentration was generally greater in the tissues of high-trophic-level fish such as Clarotes laticeps, Mormyrops anguilloides and Chrysichthys aurutus whereas low-trophic-level fish such as Oreochromis niloticus recorded low mercury concentration in their tissues. The results obtained for total mercury concentration in the muscle tissues analysed in this study are below the WHO/FAO threshold limit of 0.5 µg/g. This suggests that the exposure of the general public to Hg through fish consumption can be considered negligible.