RESUMO
Giant cell tumour of soft part is a very rare neoplasm. The majority of these tumours are located superficially (in subcutaneous tissue) and occur in the proximal parts of the extremities. The deep-situated giant cell tumours of the neck are extremely rare. That is why we report a case of primary giant cell tumour of soft part localized in the trapezius muscle of a 19-year-old woman. We present both cytological and histological picture of the neoplasm. The cytological image of the smear is so representative that the proper diagnosis can be settled basing on the fine-needle aspiration cytology.
Assuntos
Tumores de Células Gigantes/patologia , Neoplasias de Cabeça e Pescoço/patologia , Músculo Esquelético/patologia , Neoplasias de Tecidos Moles/patologia , Biomarcadores Tumorais/metabolismo , Diagnóstico Diferencial , Feminino , Tumores de Células Gigantes/metabolismo , Tumores de Células Gigantes/cirurgia , Neoplasias de Cabeça e Pescoço/metabolismo , Histiocitoma Fibroso Benigno/diagnóstico , Humanos , Osteossarcoma/diagnóstico , Sarcoma Sinovial/diagnóstico , Neoplasias de Tecidos Moles/metabolismo , Neoplasias de Tecidos Moles/cirurgia , Sinovite Pigmentada Vilonodular/diagnóstico , Resultado do Tratamento , Adulto JovemRESUMO
PEComas localized in the region of falciform ligament and broad ligament are exceedingly rare. Most of them are built of spindle neoplastic cells. We report a case of epithelioid PEComa of the falciform ligament and/or broad ligament. There is only one report of such neoplasm in English-language literature. Histologically, the tumor was composed of nests of epithelioid clear cells stained positively for vimentin, HMB45, and SMA. Because of morphological features of the tumour (4 mitoses /20HPF, focal necrosis, and vascular invasion) we assess the neoplasm as potentially malignant.
Assuntos
Ligamento Largo/patologia , Neoplasias de Células Epitelioides Perivasculares/patologia , Adulto , Biomarcadores Tumorais/análise , Ligamento Largo/metabolismo , Proteínas de Ligação a Calmodulina/genética , Feminino , Rearranjo Gênico , Humanos , Imuno-Histoquímica , Hibridização In Situ , Neoplasias de Células Epitelioides Perivasculares/genética , Neoplasias de Células Epitelioides Perivasculares/metabolismo , Proteína EWS de Ligação a RNA , Proteínas de Ligação a RNA/genéticaRESUMO
The paired ovaries of Steingelia gorodetskia are composed of about 100 telotrophic ovarioles devoid of terminal filaments (scale insect autapomorphy). In structure they resemble those of other scale insects, but differ in the following details: (a) all ovarioles develop synchronously, (b) they are suspended to the lateral oviducts by means of long stalks, (c) the tropharium is tubular (unique in scale insects) and (d) consists of 15-35, trophocytes, 2-4 previtellogenic oocytes that further develop, and numerous somatic prefollicular cells, (e) the vitellarium houses 2-4 linearly arranged vitellarial oocytes (versus one in most scale insects). Most of these features must be considered as plesiomorphic corresponding with the conditions in the most primitive Heteroptera. Bacterial endosymbionts have been found in some somatic cells, trophocytes, oocytes and in the nutritive cord. Present results support the opinion, based on external morphology, that the Steingeliidae are closely related to the Ortheziidae, Xylococcidae and Matsucoccidae.
