Granulomatous vasculitis of Churg-Strauss type in a patient with diabetes insipidus.

The CHSS was first described as an allergic granulomatosis and angiitis. This syndrome is characterized by pulmonary and systemic vasculitis, extravascular granulomas and eosinophilia which occur in patients with bronchial asthma and allergy. The CHSS in limited form may be present in an isolated organ or tissue. Despite increased awareness by clinicians, recognition of the condition can be difficult. It should be mentioned that CHSS may be a life-threatening disorder, especially via cardiac failure. Hence, an early diagnosis and treatment of this syndrome is very important, including the application of corticoids that favorably affect the course of the disease.

[Diagnosis of lung injury due to amiodarone--contribution of bronchoalveolar lavage]. / Diagnostika poskození plic amiodaronem--prínos bronchoalveolární laváze.

Based on the authors' own observation of a patient with pulmonary affection during amiodarone treatment, they demonstrate contemporary possibilities of early diagnosis of this potentially serious condition. They emphasize the importance of bronchoalveolar lavage, a non-invasive diagnostic method which provides information on the conditions in the peripheral portions of the lungs. The authors give an account of data in the literature on the pathogenesis of side effects of amiodarone in the lungs and draw attention to the need of systematic pneumological check-up examinations during treatment. If the drug is discontinued in time, all side-effects may recede spontaneously.

[Findings from a socio-medical study of acute myocardial infarct]. / Nekteré poznatky ze sociologicko-medicínského výzkumu akutního infarktu myokardu.

An investigation of the lifestyle of 80 patients with acute myocardial infarction was made in cooperation of Olomouc doctors and sociologists in 1987 and 1988. By means of questionnaires replies to 128 questions with 191 items were assembled. The findings were compared with a group of 378 people not treated on account of this disease and in some respects also with 89 patients treated in conjunction with a cerebrovascular attack. The investigation confirmed the great risk, in particular of men having responsible jobs, as well as the risk of subjects with prolonged traumas not compensated by adequate physical activities. The risk factor is work overload, prolonged mental strain, underrating of mental hygiene and psychotraining. The investigation confirmed also the negative role of a high blood pressure (frequently not treated), an unsuitable composition of the diet, overweight, diabetes. The factor of general satisfaction with professional achievements cannot balance the negative influence of these "destructive factors". As compared with a group of healthy subjects, patients had before the disease more frequently a very indifferent attitude to principles of a healthy lifestyle recommended by doctors.