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2.
Ann Surg Oncol ; 30(9): 5472-5485, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37340200

RESUMO

BACKGROUND: Involved lateral lymph nodes (LLNs) have been associated with increased local recurrence (LR) and ipsi-lateral LR (LLR) rates. However, consensus regarding the indication and type of surgical treatment for suspicious LLNs is lacking. This study evaluated the surgical treatment of LLNs in an untrained setting at a national level. METHODS: Patients who underwent additional LLN surgery were selected from a national cross-sectional cohort study regarding patients undergoing rectal cancer surgery in 69 Dutch hospitals in 2016. LLN surgery consisted of either 'node-picking' (the removal of an individual LLN) or 'partial regional node dissection' (PRND; an incomplete resection of the LLN area). For all patients with primarily enlarged (≥7 mm) LLNs, those undergoing rectal surgery with an additional LLN procedure were compared to those  undergoing only rectal resection. RESULTS: Out of 3057 patients, 64 underwent additional LLN surgery, with 4-year LR and LLR rates of 26% and 15%, respectively. Forty-eight patients (75%) had enlarged LLNs, with corresponding recurrence rates of 26% and 19%, respectively. Node-picking (n = 40) resulted in a 20% 4-year LLR, and a 14% LLR after PRND (n = 8; p = 0.677). Multivariable analysis of 158 patients with enlarged LLNs undergoing additional LLN surgery (n = 48) or rectal resection alone (n = 110) showed no significant association of LLN surgery with 4-year LR or LLR, but suggested higher recurrence risks after LLN surgery (LR: hazard ratio [HR] 1.5, 95% confidence interval [CI] 0.7-3.2, p = 0.264; LLR: HR 1.9, 95% CI 0.2-2.5, p = 0.874). CONCLUSION: Evaluation of Dutch practice in 2016 revealed that approximately one-third of patients with primarily enlarged LLNs underwent surgical treatment, mostly consisting of node-picking. Recurrence rates were not significantly affected by LLN surgery, but did suggest worse outcomes. Outcomes of LLN surgery after adequate training requires further research.


Assuntos
Excisão de Linfonodo , Neoplasias Retais , Humanos , Excisão de Linfonodo/métodos , Estudos Transversais , Linfonodos/cirurgia , Linfonodos/patologia , Neoplasias Retais/patologia , Reto/patologia , Estudos Retrospectivos , Recidiva Local de Neoplasia/cirurgia , Recidiva Local de Neoplasia/patologia , Estadiamento de Neoplasias
3.
Arthroscopy ; 30(10): 1311-6, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25023737

RESUMO

PURPOSE: The purpose of the current study was to clinically evaluate the diagnostic value of the new posterior impingement (PIM) view in the detection of an os trigonum, compared with the standard lateral view, using computed tomography (CT) as a reference standard. METHODS: Three observers, 2 experienced (orthopaedic surgeon and radiologist) and one inexperienced (resident), independently scored 142 radiographic images for the presence of an os trigonum. The diagnostic performance was assessed using the computed tomographic scan as the reference standard. Accuracy, sensitivity, specificity, positive predicted value (PPV), and negative predicted value (NPV) were calculated. RESULTS: The PIM view had significantly superior accuracy compared with the lateral view for each observer: orthopaedic surgeon, PIM view = 90 versus lateral view = 75 (P = .013); radiologist, PIM view = 80 versus lateral view = 64 (P = .019); resident, PIM view = 90 versus lateral view = 79 (P = .039). The mean sensitivity and specificity of the lateral view for all observers was 50% and 81%, respectively. For the PIM view, this was 78% and 89%, respectively. The PPV was 50% for the lateral view and 70% for the PIM view. The NPV was 84% for the lateral view and 93% for the PIM view. CONCLUSIONS: The PIM view has significantly superior diagnostic accuracy compared with the conventional lateral view in the detection of an os trigonum. In cases of symptomatic posterior ankle impingement, we advise that a PIM view be used instead of or in addition to the standard lateral view for detection of posterior talar pathologic conditions. LEVEL OF  EVIDENCE: Level II, development of diagnostic criteria on basis of consecutive patients with universally applied reference gold standard.


Assuntos
Articulação do Tornozelo/diagnóstico por imagem , Tornozelo/diagnóstico por imagem , Artropatias/diagnóstico por imagem , Tálus/diagnóstico por imagem , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Síndrome , Tomografia Computadorizada por Raios X
4.
Orthopedics ; 36(4): e457-62, 2013 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-23590785

RESUMO

Over the past decade, several anatomical plates have been introduced to improve the result of open reduction and internal fixation of the distal radius. Using 3-dimensional imaging techniques, the authors studied the accuracy and reproducibility of distal radius positioning using anatomical plates.Distal radius fractures and the correction of these fractures were simulated with plastic bone models of radii. The authors simulated a defect by removing an arbitrary wedge shape from the artificial radii. Two surgeons corrected these fractures by placing 2 anatomical plate types according to the plate manufacturers' instructions. The residual positioning errors of the distal segment in relation to the unaffected radii were determined using 3-dimensional imaging and were compared with naturally occurring bilateral radius differences in healthy individuals. In many cases, positioning does not agree with differences based on bilateral asymmetry in healthy patients.This study indicated the accuracy of anatomical plates. Positioning an anatomical plate may lead to considerable residual errors in individual patients. Volar distal radius plate shapes differ among plate manufacturers. Therefore, one plate may perform better than another in an individual.


Assuntos
Placas Ósseas , Fixação Interna de Fraturas , Fraturas do Rádio/cirurgia , Rádio (Anatomia)/cirurgia , Feminino , Humanos , Masculino , Modelos Anatômicos , Adulto Jovem
5.
Orthopedics ; 36(2): e193-9, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23380014

RESUMO

The authors retrospectively investigated the postoperative position of the distal radius after a corrective osteotomy using 2-dimensional (2-D) and 3-dimensional (3-D) imaging techniques to determine whether malposition correlates with clinical outcome. Twenty-five patients who underwent a corrective osteotomy were available for follow-up. The residual positioning errors of the distal end were determined retrospectively using standard 2-D radiographs and 3-D computed tomography evaluations based on a scan of both forearms, with the contralateral healthy radius serving as reference. For 3-D analysis, use of an anatomical coordinate system for each reference bone allowed the authors to express the residual malalignment parameters in displacements (Δx, Δy, Δz) and rotations (Δφx, Δφy, Δφz) for aligning the affected bone in a standardized way with the corresponding reference bone. The authors investigated possible correlations between malalignment parameters and clinical outcome using patients' questionnaires. Two-dimensional radiographic evaluation showed a radial inclination of 24.9°±6.8°, a palmar tilt of 4.5°±8.6°, and an ulnar variance of 0.8±1.7 mm. With 3-D analysis, residual displacements were 2.6±3 (Δx), 2.4±3 (Δy), and -2.2±4 (Δz) mm. Residual rotations were -6.2°±10° (Δφx), 0.3°±7° (Δφy), and -5.1°±10° (Δφz). The large standard deviation is indicative of persistent malalignment in individual cases. Statistically significant correlations were found between 3-D rotational deficits and clinical outcome but not between 2-D evaluation parameters. Considerable residual malalignments and statistically significant correlations between malalignment parameters and clinical outcome confirm the need for better positioning techniques.


Assuntos
Fraturas Mal-Unidas/diagnóstico por imagem , Osteotomia , Fraturas do Rádio/diagnóstico por imagem , Adulto , Idoso , Feminino , Fraturas Mal-Unidas/cirurgia , Humanos , Imageamento Tridimensional , Masculino , Pessoa de Meia-Idade , Postura , Fraturas do Rádio/cirurgia , Estudos Retrospectivos , Tomografia Computadorizada por Raios X
6.
J Hand Surg Am ; 33(5): 740-5, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18590858

RESUMO

PURPOSE: Peripheral articular denervation has been proposed as an alternative treatment for degenerative arthritis. It shows particular promise in the elbow because the joint is non-weight bearing and easily exposed. Accurate knowledge of peripheral neuroanatomy is required for future denervation surgeries, yet very few studies focus on the articular branches of the ulnar, median, and radial nerves that provide elbow capsule innervation. METHODS: Twenty-three upper limbs from skeletally mature fresh-frozen cadavers were used for dissection of the ulnar, median, and radial nerves. The presence, number, location, and diameter of articular branches to the elbow capsule were recorded. RESULTS: The ulnar nerve typically supplied 1 to 2 large branches to the elbow capsule (range, 0-4). In the 3 specimens with a greater number, a thinner diameter was noted (<1 mm compared with 1.2 mm). The median nerve contributed an average of 1.3 branches (range, 0-4) and showed an inverse ratio with the ulnar nerve contribution. The posterior interosseous nerve contributed a range of 0 to 4 branches, arising at 5 mm to 2 mm after bifurcation of the radial nerve. CONCLUSIONS: Most previous upper-extremity nerve studies have failed to fully characterize the contributions of all 3 major nerves to capsular innervation. We have thoroughly documented the articular branching patterns of all 3 major nerves and show that all 3 may contribute branches to the capsule.


Assuntos
Denervação/métodos , Articulação do Cotovelo/inervação , Nervo Mediano/anatomia & histologia , Nervo Radial/anatomia & histologia , Nervo Ulnar/anatomia & histologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Cadáver , Dissecação , Articulação do Cotovelo/cirurgia , Humanos , Pessoa de Meia-Idade
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