Risk factors of anemia among pregnant women in community health center (Puskesmas) Singgani and Puskesmas Tipo Palu.

OBJECTIVE: The aim of this study is to describe the risk factors of anemia among pregnant women. METHOD: We used an observational analytic study with a matched case-control study design. The sampling method used in this study is a simple random sampling technique. The sample size in this study is 138 samples that consist of 46 cases and 92 controls. The data obtained from patient medical records and analyzed statistically using the chi-square test. RESULTS: Nutritional status is a risk factor of anemia among pregnant women in Community Health Center (Puskesmas) Singgani and Puskesmas Tipo. The risk of pregnant women with chronic energy deficiency (CED) developing anemia is higher in Puskesmas Singgani compared to in Puskesmas Tipo. CONCLUSION: Prevention can be done by counseling the bride and groom about pregnancy preparation and counseling the pregnant women to pay attention to the nutritional intake, particularly the consumption of folic acid supplements and iron.

The determinant of work stress on bank employees in Makassar, Indonesia.

OBJECTIVE: The purpose of this study was to determine the factors associated with work stress on employees at the BNI Makassar Branch Office. METHODS: This study used a cross-sectional research design. The sample was taken using a simple random sampling technique. The data were processed using the SPSS program, the results of which were presented in tables and narrative form. RESULT: The results showed that the variable work stress relationship with the workload and gender variables of the employees at the BNI Makassar Regional Office. And there is no stress on the work relationship with the variables of marital status, years of service, and length of work for employees at the BNI Makassar Regional Branch Office. CONCLUSION: Workload and gender have a significant relationship with work stress. The suggestions for minimizing the level of work stress with stress management.

Community Health Risk Assessment of Total Suspended Particulates near a Cement Plant in Maros Regency, Indonesia.

BACKGROUND: Cement plants generate particulate matter (PM) across processes from raw material preparation to packaging. The presence of total suspended particulates (TSP) coming out of the stack causes a high accumulation of dust in residential areas. Human exposure to TSP could affect human health and wellbeing. OBJECTIVES: The present study aims to evaluate concentrations of TSP and to estimate the health risks of TSP exposure through the inhalation pathway in communities surrounding a private cement industry in Maros regency, Indonesia. METHODS: Total suspended particulates were collected using a high-volume air sampler (HVAS) at five locations. Samples were taken by grab sampling for 24 hours. The SCREEN3 program was used to view the maximum range and distribution of pollutants based on the geographical, stack profiles and meteorological factors in the study area. Hazard quotient (HQ) was used to estimate non-carcinogenic risks of TSP in surrounding communities. RESULTS: Total suspended particulate concentrations were measured with a maximum value of 133.24 µg/m3 and a minimum value of 18.48 µg/m3. This maximum value exceeds the minimum acceptable level from Canadian National Ambient Air Quality Objectives (C-NAAQOs). The non-carcinogenic risks from the inhalation pathway were low except for location 3 (HQ>1) across all locations. CONCLUSIONS: The cement plant may significantly contribute to total TSP concentrations in air and may potentially have adverse effects on human health. Communities near the cement plant are vulnerable to TSP exposure and measures are needed to reduce TSP in Maros regency, Indonesia. PARTICIPANT CONSENT: Obtained. ETHICS APPROVAL: This study was approved by the Health Research Ethics Committee of Hasanuddin University with protocol number 28920093022. COMPETING INTERESTS: The authors declare no competing financial interests.

Risk factors of anemia among pregnant women in community health center (Puskesmas) Singgani and Puskesmas Tipo Palu

Objective: The aim of this study is to describe the risk factors of anemia among pregnant women. Method: We used an observational analytic study with a matched case-control study design. The sampling method used in this study is a simple random sampling technique. The sample size in this study is 138 samples that consist of 46 cases and 92 controls. The data obtained from patient medical records and analyzed statistically using the chi-square test. Results: Nutritional status is a risk factor of anemia among pregnant women in Community Health Center (Puskesmas) Singgani and Puskesmas Tipo. The risk of pregnant women with chronic energy deficiency (CED) developing anemia is higher in Puskesmas Singgani compared to in Puskesmas Tipo. Conclusion: Prevention can be done by counseling the bride and groom about pregnancy preparation and counseling the pregnant women to pay attention to the nutritional intake, particularly the consumption of folic acid supplements and iron. (AU)

The determinant of work stress on bank employees in Makassar, Indonesia

Objective: The purpose of this study was to determine the factors associated with work stress on employees at the BNI Makassar Branch Office. Methods: This study used a cross-sectional research design. The sample was taken using a simple random sampling technique. The data were processed using the SPSS program, the results of which were presented in tables and narrative form. Result: The results showed that the variable work stress relationship with the workload and gender variables of the employees at the BNI Makassar Regional Office. And there is no stress on the work relationship with the variables of marital status, years of service, and length of work for employees at the BNI Makassar Regional Branch Office. Conclusion: Workload and gender have a significant relationship with work stress. The suggestions for minimizing the level of work stress with stress management. (AU)

Requirement Prediction for Toluene Detox with Foods Intake Rich in CYP2E1 Enzyme and Glycine to Prevent Nerve and Kidney Damage at Shoe Home Industry Workers in Romokalisari Surabaya.

BACKGROUND: Toluene was an organic compound used in chemical and drug industries, the main source of toluene emissions from fires. To reduce and even eliminate toluene toxins in chemical component could be using detoxification by foods. AIM: This research aimed to calculate the intake of foods rich in CYP2E1 enzyme and glycine to improve toluene detoxification. METHODS: The type of research was a descriptive study. The subject of the study was 51 workers in Romokalisari Surabaya who had worked for more than or equal to 10 years. Variables were body weight, duration of working (years), working time per week (days), and working time per day (hours). The breathing rate, intake of non-carcinogen per respondent, can be calculated by variables before. Then, the effective dose of food rich in CYP2E1 enzyme and glycine will be obtained. RESULTS: Majority respondents had toluene concentrations below the threshold limit value (TLV). The highest effective dose of foods rich in CYP2E1 enzymes such as beef liver, beef brain, and salmon was 239.61 g, 745.45 g, and 203.3 g. Also, foods rich in glycines such as seaweed, tuna, and spinach were 432.98 mg, 934.41 mg, and 2070.71 mg. CONCLUSION: The level of adequacy of the CYP2E1 enzyme and glycine of each person was different and varied. The effective dose required by each respondent depending on weight, length of work, and concentration of benzene in the workplace. The greater the toluene concentration, the greater the needs for foods rich in CYP2E1 enzymes and glycine. Body weight can also be another factor in differences in individual intake. Weight, length of working, and toluene concentration can affect the intake of non-carcinogen in each which can affect the effective dose of foods.

Determination of Highest Dose of Ammonia without Effect at Work Environment through the Expression of Interleukin-2 Cell in Rattus Novergicus.

BACKGROUND: For determining the threshold limit value firstly determined the highest dose of ammonia without effect (NOAEL). However, research on the determination of NOAEL ammonia didn't conduct in Indonesia. AIM: The aim of this study to determine the value of the highest dose of ammonia without effect (No Observed Adverse Effect Level/NOAEL) through interleukin-2 (IL-2) expression on white mice. METHODS: This study used experimental laboratory research with post-test only control group design using white mice as experimental subjects. The treatment group divided into 6 groups (a group of controls and five groups with different ammonia exposure through inhalation). The trend curve of Remmele Scale Index (IRS) and histopathologic analysis could be used for determining NOAEL. RESULT: The location of the highest dose of ammonia without any effect (NOAEL) of white mice was in the second group, with 0.0103 mg/kg body weight dose. Analysis of statistical tests Kruskal Wallis stated there was no significant difference in interleukin-2 expression between the control with ammonia exposed group with a significance of p (0.747) > α (0.05). CONCLUSION: There is no difference between some interleukin-2 expression in the lymphocyte cell lung white mice group exposed to ammonia and control group. The highest dose of ammonia without any effect (NOAEL) on white mice was 0.0103 mg/kg body weight.

Relationship of Benzene Exposure to Trans, Trans-Muconic Acid and Blood Profile of Shoe Workers in Romokalisari Surabaya, Indonesia.

BACKGROUND: Benzene is a hazardous ingredient for health. Benzene is used as a latex glue solvent in the shoe industry. AIM: The purpose of the study was to analyse the relationship between benzene exposure with trans, trans-muconic acid (t, t-MA) and the blood profile of shoe workers in Romokalisari Surabaya. METHODS: The study was a cross-sectional design conducted in the shoe industry in Romokalisari Surabaya with some subjects of 20 shoe workers. Data collection was carried out by measuring benzene levels conducted at 8 measurement points in Surabaya Romokalisari, taking workers' blood, measuring body weight and conducting interviews with respondents. Data were analysed using correlation tests. RESULTS: The results showed that there was no relationship between benzene levels with t, t-MA (p-value = 0.205), there was no relationship between benzene Risk Quotient (RQ) and t, t-MA (p-value = 0.271) and there was no relationship between the Excess Cancer Risk (ECR) and blood profile of workers in Romokalisari. However, there were some abnormal blood profile parameters due to exposure to benzene although it was small. CONCLUSIONS: It seems another factors such as length of work, nutritional status, duration of exposure, weight, and frequency of exposure have a considerable contribution in the determination of intake of xenobiotic ingredients in the body to cause health effects especially blood profiles.

The Cost Prediction for Chromium Detox Using Foods Intake Containing Glutathione at the Leather Tanning Industry in Magetan, Indonesia.

BACKGROUND: Chromium was an organic compound which was used in metal alloys such as stainless steel, chrome plating, metal ceramics, leather tanning, etc. To reduce and eliminate toxin of chromium from the human body could be using detoxification process, one of them was using foods. AIM: The aim was to calculate the foods intake contain glutathione to improve chromium detoxification and calculate the cost of foods intake. METHOD: The type of research was a descriptive study. The subjects were 10 workers. Inclusion criteria of subjects were workers who had worked for more than or equal to 10 years. Variables were body weight, duration of work, and chromium concentration. After getting all variables above, breathing rate and intake non-carcinogen per respondent can be calculated. Then, the effective dose of foods rich in glutathione and costs of foods will be obtained. RESULTS: The results of this research indicated that the highest cost of foods intake containing glutathione was 5948 idr of broccoli per week and the lowest cost of foods intake was 535 idr of avocado per week. CONCLUSION: Intake of foods containing glutathione (avocado, broccoli, carrot, tomato, and grape) was expected to increase detoxification of chromium. Each individual had a different amount of cost. This depends on the effective dose, chromium concentration, weight, and duration of work per respondent.

Risk Analysis Characterization of Benzene and Demographic Factors toward Immunoglobulin A.

BACKGROUND: Research on risk assessment at industrial sites has experienced growth during the end of this year. But in Indonesia, there is still limited research on risk assessment, especially regarding the importance of measuring non-carcinogenic risk assessment in the workplace. Benzene exposure is believed to reduce levels of immunoglobulin A (IgA) in workers. AIM: The purpose of this study was to analyse the relationship between risk quotient (RQ) of non-carcinogenic risk assessment of benzene and demographic factors on IgA levels. MATERIAL AND METHODS: The subjects of the study were shoe craftsmen who were at risk of benzene exposure. The study design was cross-sectional with a total population of 20 workers. Measurement of IgA levels by Immunoturbidimetric Assay with a normal standard of 2-3 mg/ml. Calculation of non-carcinogenic (RQ) risk characteristics with a comparison between risk agent non-carcinogenic intake with RfD or RfC benzene. RESULTS: The majority of the study subjects aged over 45 years and had a working period of ≥ 25 years. There were 2 location points that had a threshold value exceeding the benzene standard (> 0.05 ppm), and 40% of the subjects had decreased IgA levels. Age and working periods had a significant relationship to IgA levels (p = 0.027; p = 0.047), while benzene and RQ levels did not have a significant relationship with IgA levels (p = 0.179; p = 0.436). CONCLUSION: Increasing age and working period can reduce IgA levels in the body. Further research is needed on risk assessment, especially on the safe limits of benzene concentration in the workplace to find out how long benzene exposure forms a non-carcinogenic or carcinogenic risk in workers' bodies exposed to benzene.