RESUMO
In 52 normal subjects there was an inverse relationship between serum ferritin concentration and iron absorption. In 21 measurements in 15 patients with idiopathic haemochromatosis there was a similar inverse relationship but absorption was higher in relation to iron stores at all levels. Haemochromatotic patients with normal serum ferritin levels had abnormally high values for desferrioxamine chelatable iron and there was no correlation between chelatable iron and iron absorption.
Assuntos
Ferritinas/sangue , Hemocromatose/metabolismo , Absorção Intestinal , Ferro/metabolismo , Adulto , Desferroxamina , Feminino , Hemocromatose/sangue , Hemoglobinas/análise , Humanos , Ferro/sangue , Radioisótopos de Ferro , Masculino , Fatores Sexuais , Transferrina/análise , Contagem Corporal TotalAssuntos
Anemia Hipocrômica , Deficiências de Ferro , Anemia Hipocrômica/diagnóstico , Anemia Hipocrômica/tratamento farmacológico , Anemia Hipocrômica/epidemiologia , Anemia Hipocrômica/etiologia , Criança , Diagnóstico Diferencial , Dieta , Feminino , Humanos , Lactente , Ferro/administração & dosagem , Ferro/metabolismo , Ferro/uso terapêutico , Masculino , Menstruação , Necessidades Nutricionais , Nutrição Parenteral , GravidezRESUMO
The relationship between serum ferritin concentration and the amount of storage iron has been studied in normal subjects. A high degree of correlation was demonstrated between serum ferritin concentration and storage iron measured by quantitative phlebotomy. The possible advantages of assessing iron stores by using the serum ferritin concentration are discussed.
