Formation of small-granule starch oleogels based on capillary force: Impact of starch surface lipids on lubrication performance.

Starch granule oleogels were prepared and their rheological properties were precisely tuned using the capillary bridging phenomenon. The addition of a small amount of water to an oily suspension of starch granules can lead to starch granule bridging and network formation, transitioning it from a fluid-like to a gel-like state. Small-granule starches with high specific surface area and interfacial area exhibited a greater number of liquid bridges and stronger starch granules interactions, making them more prone to forming structurally stable oleogel systems. By increasing the content of water and starch granule, the starch oleogels exhibited three distinct structural states: pendular state (water ≤ 3.28 %, starch ≤ 17.85 %), pendular bridging network (water: 4.92 %, starch: 24.59 %), and capillary aggregates (water ≥ 6.56 %, starch > 24.59 %). Furthermore, the influence of starch granule surface lipids on the lubrication performance of the oleogel system was investigated. Surface roughness increased after extraction of surface lipids, and the friction coefficient also showed a significant increase. Overall, capillary suspension system can potentially be used to design novel fat food products, and our findings have established the correlation between starch granule surface properties and sensory perception in food, providing valuable insights for adjusting the oral processing characteristics of food.

Polyphenol-Enriched Protein Oleogels as Potential Delivery Systems of Omega-3 Fatty Acids.

Omega-3 polyunsaturated fatty acids (n-3 FAs) are essential nutrients and are considered effective in improving human health. Recent studies highlight the importance of the combination of n-3 FAs and polyphenols for limiting the oxidation of n-3 FAs and exhibiting synergistic beneficial effects. Herein, we developed a novel formulation technology to prepare oleogels that could be used for the codelivery of n-3 FAs and polyphenols with high loading efficacy and oxidative stability. These oleogels are made from algal oil with polyphenol-enriched whey protein microgel (WPM) particles as gelling agents via simple and scalable ball milling technology. The oxidative status, fatty acid composition, and volatiles of protein oleogels during accelerated storage were systematically assessed by stoichiometry and gas chromatography-mass spectrometry. These results showed that protein oleogels could overcome several challenges associated with the formulation of n-3 oils, including long-term oxidative stability and improved sensory and textural properties. The protein oleogel system could provide an excellent convenience for formulating multiple nutrients and nutraceuticals with integrating health effects, which are expected to be used in the care of highly vulnerable populations, including children, the elderly, and patients.

Exploring potential opportunities for the efficient development of the cobalt industry in China by quantitatively tracking cobalt flows during the entire life cycle from 2000 to 2021.

Owing to its key role in high-tech industry and clean energy technology, cobalt has been regarded as a critical material in many countries. In this paper, material flow analysis was used to quantitatively track cobalt material flows in China throughout the entire life cycle from 2000 to 2021. Based on data pertaining to cobalt commodity trade, cobalt loss during raw material processing, and recovered cobalt, we analysed the actual cobalt consumption in China. During the study period from 2000 to 2021, the main findings were as follows: (1) China's cobalt raw material imports accounted for 84.7% of the total raw materials acquired, while the export of cobalt-containing end products amounted to 32.6% of the total production. (2) China's cumulative net import of all cobalt commodities reached 561 kt, and battery products accounted for 73.3% of the total cobalt consumption. (3) China recovered 77 kt of cobalt from end-of-life products, while 327 kt of cobalt was not recovered. (4) The cumulative cobalt loss during raw material processing reached 288 kt, with the highest loss occurring in refining (51.0%), followed by manufacturing and fabrication (26.5%), beneficiation (12.3%), and ore mining (10.2%). The overall utilization efficiency of cobalt was 73.8% throughout the entire life cycle. (5) China's actual cobalt consumption reached 497 kt, accounting for 51.9% of the apparent cobalt consumption. Moreover, 61.1% of the cobalt products produced in China was consumed domestically, while 38.9% was exported. The massive export of cobalt commodities resulted in China bearing a disproportionate responsibility for carbon emission reduction. The research results can provide a scientific reference for the reasonable adjustment of the trade structure of cobalt commodities and realization of the economic and efficient utilization of cobalt resources in China.

Salt reduction in bread via enrichment of dietary fiber containing sodium and calcium.

The high intake of sodium and low intake of dietary fiber are two major dietary risk factors for preventable deaths worldwide, highlighting the need and implementations for developing health foods with low-salt/high-dietary fibers. Bread as a staple food contributes about 25% to the daily intake of sodium in many countries, and salt reduction in bread still remains a great technical challenge. In this study, we developed a simple method to reformulate the white bread in terms of reducing salt contents via dietary fiber fortification, while maintaining the taste and texture qualities. Low molecular weight water-extractable arabinoxylans (LMW-WEAX) as a soluble dietary fiber was first hydrated in salt water before dough mixing, leading to an inhomogeneous spatial distribution of sodium in bread and accelerating the release of sodium ions from crumbs, allowing 20% salt reduction in bread without impacting the salt perception. Data from the moisture content, crumb structure, water distribution, dough rheology and bread texture properties suggest that the pre-hydrated incorporation of LMW-WEAX mitigates the detrimental effect of dietary fiber on the dough and bread quality. The modulation of Ca2+ on the permeability of Na+ through the mucus layer and implication in salt enhancement of the bread were investigated. Results show that the pre-hydrated incorporation of WEAX containing Na+ and Ca2+ (1.0%) makes it possible to reduce 30% salt content in breads, which have implications in the large-scale production of low-salt/high-dietary fiber bread.

Potential impact of the end-of-life batteries recycling of electric vehicles on lithium demand in China: 2010-2050.

China is expected to realise the complete electrification of traditional internal combustion engine vehicles (ICEVs) by 2050. The rapid development of electric vehicles (EVs) has led to the continuous growth of traction lithium-ion battery (LIB) demand, leading to an increase in demand for specific lithium materials. Therefore, end-of-life (EoL) LIB recycling will largely determine the future lithium availability in China. However, the contribution of recovered lithium to lithium availability is unclear, as the possibility of recovering lithium for reuse in traction LIBs manufacturing is uncertain. To analyse the influence of recovered lithium quality on future lithium availability, we evaluated the potential impact of EoL LIB recycling on lithium demand in China. The results indicated that if new LIB manufacturing cannot use the recovered lithium; the secondary resources would soon exceed the needs of the basic demand (BD) field. In the optimistic scenario, when a LiS battery is used, the oversupply could reach 2.33 Mt by 2050 with a recovery rate of 80%, which is equivalent to 44.05% of China's current lithium reserves of 5.29 Mt. Additionally, when the NCM-G battery is used, the total lithium demand would reach approximately 5.67 Mt in 2031, exceeding China's current lithium reserves. In contrast, if the recovered lithium could be reused in new LIB manufacturing, regardless of the type of LIBs used, the recovered lithium would meet approximately 60% (pessimistic scenario), 53% (neutral scenario), and 49% (optimistic scenario) of the lithium demand for LIBs produced with a recovery rate of 80% by 2050. Consequently, the quality of recovered lithium is very important for its reuse, and it is necessary to develop closed-loop recycling with economic benefits vigorously by improving the quality of recovered lithium. Moreover, much work should be done in recycling infrastructure and industrial policies to promote EoL battery recycling.

3D Culture System for Liver Tissue Mimicking Hepatic Plates for Improvement of Human Hepatocyte (C3A) Function and Polarity.

In vitro 3D hepatocyte culture constitutes a core aspect of liver tissue engineering. However, conventional 3D cultures are unable to maintain hepatocyte polarity, functional phenotype, or viability. Here, we employed microfluidic chip technology combined with natural alginate hydrogels to construct 3D liver tissues mimicking hepatic plates. We comprehensively evaluated cultured hepatocyte viability, function, and polarity. Transcriptome sequencing was used to analyze changes in hepatocyte polarity pathways. The data indicate that, as culture duration increases, the viability, function, polarity, mRNA expression, and ultrastructure of the hepatic plate mimetic 3D hepatocytes are enhanced. Furthermore, hepatic plate mimetic 3D cultures can promote changes in the bile secretion pathway via effector mechanisms associated with nuclear receptors, bile uptake, and efflux transporters. This study provides a scientific basis and strong evidence for the physiological structures of bionic livers prepared using 3D cultures. The systems and cultured liver tissues described here may serve as a better in vitro 3D culture platform and basic unit for varied applications, including drug development, hepatocyte polarity research, bioartificial liver bioreactor design, and tissue and organ construction for liver tissue engineering or cholestatic liver injury.

Pollution, sources and environmental risk assessment of heavy metals in the surface AMD water, sediments and surface soils around unexploited Rona Cu deposit, Tibet, China.

The pollution by heavy metals (HMs) of mining is a widespread problem in the world. However, the pollution by HMs around unexploited deposits (virgin fields) has been studied rarely, especially in Tibet, China. Water, sediments and surface soils were collected to investigate the concentrations of HMs around unexploited Rona Cu deposit in Tibet, China. Furthermore, geochemical fractions of these elements were also analyzed. Pollution and environmental risk introduced by HMs accumulation were assessed using pollution indices, geo-accumulation (Igeo), potential ecological risk index and risk assessment code (RAC). Results indicated that the pH values of Rona tributary river ranged from 2.70 to 3.08, and the average concentrations of Cu and Zn were 2114.00 ± 65.89 and 1402.14 ± 27.36 µg L-1, respectively, exceeding their standard limits. The concentrations (mg kg-1) of Cu, Zn and As ranged in 19.01-1763.10, 62.00-543.06 and 11.12-61.78 for sediments, respectively, and 154.60-1489.35, 55.38-344.74 and 10.05-404.03 for surface soils, respectively, exceeding their standard limits. According to RAC, almost all Cu, Zn and As near low risk status. However, Cd ranged from medium to very high risk in sediments, and low to high risk in surface soils. Statistical analysis suggested that Cu, Pb, Zn, As and Cd in sediments and surface soils may mainly derive from Rona deposit, whereas Cr and Hg may primarily originate from lithogenic sources. The results indicated that very high concentrations of HMs could be occurred in surface water, sediments and surface soils around unexploited deposits. Especially at high-altitude Tibet, the high environmental risk of HMs deserves more attention.

Product and Metal Stocks Accumulation of China's Megacities: Patterns, Drivers, and Implications.

The rapid urbanization in China since the 1970s has led to an exponential growth of metal stocks (MS) in use in cities. A retrospect on the quantity, quality, and patterns of these MS is a prerequisite for projecting future metal demand, identifying urban mining potentials of metals, and informing sustainable urbanization strategies. Here, we deployed a bottom-up stock accounting method to estimate stocks of iron, copper, and aluminum embodied in 51 categories of products and infrastructure across 10 Chinese megacities from 1980 to 2016. We found that the MS in Chinese megacities had reached a level of 2.6-6.3 t/cap (on average 3.7 t/cap for iron, 58 kg/cap for copper, and 151 kg/cap for aluminum) in 2016, which still remained behind the level of western cities or potential saturation level on the country level (e.g., approximately 13 t/cap for iron). Economic development was identified as the most powerful driver for MS growth based on an IPAT decomposition analysis, indicating further increase in MS as China's urbanization and economic growth continues in the next decades. The latecomer cities should therefore explore a wide range of strategies, from urban planning to economy structure to regulations, for a transition toward more "metal-efficient" urbanization pathways.

Fabrication of agarose concave petridish for 3D-culture microarray method for spheroids formation of hepatic cells.

Liver is one of the most important organ in the body. But there are many limitations about liver transplantation for liver failure. It is quite important to develop the xenogeneic biological liver for providing an alternation to transplantation or liver regeneration. In this paper, we proposed a method to construct a novel kind of agarose 3D-culture concave microwell array for spheroids formation of hepatic cells. Using the 3D printing method, the microwell array was fabricated with an overall size of 6.4 mm × 6.4 mm, containing 121 microwells with 400 µm width/400 µm thickness. By exploiting the Polydimethylsiloxane (PDMS) membranes as a bridge, we finally fabricated the agarose one. We co-cultured three types of liver cells with bionics design in the microwell arrays. Using the methods described above, the resulting co-formed hepatocyte spheroids maintained the high viability and stable liver-specific functions. This engineered agarose concave microwell array could be a potentially useful tool for forming the elements for biological liver support. After developing the complete system, we also would consider to scale up the application of this system. It will be not only applied to the therapy of human organ damage, but also to the development of disease models and drug screening models.

Synthesis of Ricinoleic Acid Estolides by the Esterification of Ricinoleic Acids Using Functional Acid Ionic Liquids as Catalysts.

Estolides of ricinoleic acid (RA) have been used as lubricants and pigment dispersant in many industries. In this paper, functional acid ionic liquids (ILs) were firstly used as catalysts to prepare RA estolides by the esterification of RAs in solvent-free system. Different ILs were used as catalysts for the esterification. Effect of reaction variables (IL amount, reaction temperature and reaction time) on the esterification were also investigated and optimized using response surface methodology (RSM). Among all tested ILs, [BSO3HMIM]TS showed the best performance for the esterification. Arrhenius equation for the esterification was lnV0 =14.897-7558.7/T, and the activation energy (Ea) was 62.84 kJ/mol. A high degree of polymerization with an acid value of 48.0±2.5 mg KOH/g was achieved at the optimized conditions (IL load 12%, reaction temperature 140°C, and reaction time 12 h). The effect of reaction variables on the esterification decreased in the order of catalyst loading of IL > reaction temperature > reaction time.