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Two-dimensional direct numerical simulations of partitioned thermal convection are performed using the thermal lattice Boltzmann method for the Rayleigh number (Ra) of 109 and the Prandtl number (Pr) of 7.02 (water). The influence of the partition walls on the thermal boundary layer is mainly focused on. Moreover, to better describe the spatially nonuniform thermal boundary layer, the definition of the thermal boundary layer is extended. The numerical simulation results show that the gap length significantly affects the thermal boundary layer and Nusselt number (Nu). The gap length and partition wall thickness have a coupled effect on the thermal boundary layer and the heat flux. Based on the shape of the thermal boundary layer distribution, two different heat transfer models are identified at different gap lengths. This study provides a basis for improving the understanding of the effect of partitions on the thermal boundary layer in thermal convection.
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The effect of rotation on small-scale characteristics and scaling law in the mixing zone of the three-dimensional turbulent Rayleigh-Taylor instability (RTI) is investigated by the lattice Boltzmann method at small Atwood number. The mixing zone width h(t), the root mean square of small scale fluctuation, the spectra, and the structure functions are obtained to analyze the rotating effect. We mainly focus on the process of the development of plumes and discuss the physical mechanism in the mixing zone in rotating and nonrotating systems. The variation of kinetic energy spectra E_{u} and temperature energy spectra E_{θ} with the dimensionless rotation Ωτ demonstrate the suppression effect of rotation. Two scaling laws between the mixing layer width h(t) and dimensionless time t/τ are obtained at various Coriolis forces(sqrt[h(t)]≃t^{0.9} and sqrt[h(t)]≃t^{0.35}). The rotation increasingly suppresses the growth of the mixing layer width h(t). The velocity and temperature fluctuations are also suppressed by the rotation effect. The relation between the Nusselt number (Nu) and the Rayleigh number (Ra) indicates that the heat transfer is suppressed by the rotation effect in the rotating RT system. The width of the inertial subrange increasingly narrows with increasing Ωτ.
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In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content, and the distribution of entropy generation before and after an operation, the effects of septal defect on pulmonary hypertension(PH), cyanosis, and heart load were analyzed in detail. It is found that the atrial septal defect(ASD) of the child we analyzed had a great influence on the blood oxygen content in the pulmonary artery, which leads to lower efficiency of oxygen binding in the lungs and increases the burden on the heart. At the same time, it also significantly enhanced the entropy generation rate of the cardiac flow, which also leads to a higher heart load. However, the main cause of PH is not ASD, but ventricular septal defect (VSD). Meanwhile, it significantly reduced the blood oxygen content in the brachiocephalic trunk, but rarely affects the blood oxygen contents in the downstream left common carotid artery, left subclavian artery, and descending aorta are not significantly affected by VSD. It causes severe cyanosis on the face and lips.
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Graph node embedding aims at learning a vector representation for all nodes given a graph. It is a central problem in many machine learning tasks (e.g., node classification, recommendation, community detection). The key problem in graph node embedding lies in how to define the dependence to neighbors. Existing approaches specify (either explicitly or implicitly) certain dependencies on neighbors, which may lead to loss of subtle but important structural information within the graph and other dependencies among neighbors. This intrigues us to ask the question: can we design a model to give the adaptive flexibility of dependencies to each node's neighborhood. In this paper, we propose a novel graph node embedding method (named PINE) via a novel notion of partial permutation invariant set function, to capture any possible dependence. Our method 1) can learn an arbitrary form of the representation function from the neighborhood, without losing any potential dependence structures, and 2) is applicable to both homogeneous and heterogeneous graph embedding, the latter of which is challenged by the diversity of node types. Furthermore, we provide theoretical guarantee for the representation capability of our method for general homogeneous and heterogeneous graphs. Empirical evaluation results on benchmark data sets show that our proposed PINE method outperforms the state-of-the-art approaches on producing node vectors for various learning tasks of both homogeneous and heterogeneous graphs.
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Time evolution features of kinetic and thermal entropy generation rates in turbulent Rayleigh-Bénard (RB) convection with mixed insulating and conducting boundary conditions at Ra = 109 are numerically investigated using the lattice Boltzmann method. The state of flow gradually develops from laminar flow to full turbulent thermal convection motion, and further evolves from full turbulent thermal convection to dissipation flow in the process of turbulent energy transfer. It was seen that the viscous, thermal, and total entropy generation rates gradually increase in wide range of t/τ < 32 with temporal evolution. However, the viscous, thermal, and total entropy generation rates evidently decrease at time t/τ = 64 compared to that of early time. The probability density function distributions, spatial-temporal features of the viscous, thermal, and total entropy generation rates in the closed system provide significant physical insight into the process of the energy injection, the kinetic energy, the kinetic energy transfer, the thermal energy transfer, the viscous dissipated flow and thermal dissipation.
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Entropy generation in thermal convection with differentially discrete heat boundary conditions at various Rayleigh numbers (Ra) are numerically investigated using the lattice Boltzmann method. We mainly focused on the effects of Ra and discrete heat boundary conditions on entropy generation in thermal convection according to the minimal entropy generation principle. The results showed that the presence of the discrete heat source at the bottom boundary promotes the transition to a substantial convection, and the viscous entropy generation rate (Su) generally increases in magnitude at the central region of the channel with increasing Ra. Total entropy generation rate (S) and thermal entropy generation rate (Sθ) are larger in magnitude in the region with the largest temperature gradient in the channel. Our results also indicated that the thermal entropy generation, viscous entropy generation, and total entropy generation increase exponentially with the increase of Rayleigh number. It is noted that lower percentage of single heat source area in the bottom boundary increases the intensities of viscous entropy generation, thermal entropy generation and total entropy generation. Comparing with the classical homogeneous thermal convection, the thermal entropy generation, viscous entropy generation, and total entropy generation are improved by the presence of discrete heat sources at the bottom boundary.
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A numerical investigation has been carried out to understand the mechanism of the rotation effect on bifurcation and dual solutions in natural convection within a horizontal annulus. A thermal immersed boundary-lattice Boltzmann method was used to resolve the annular flow domain covered by a Cartesian mesh. The Rayleigh number based on the gap width is fixed at 104. The rotation effect on the natural convection is analyzed by streamlines, isotherms, phase portrait and bifurcation diagram. Our results manifest the existence of three convection patterns in a horizontal annulus with rotating inner cylinder which affect the heat transfer in different ways, and the linear speed ( U i * ) determines the proportion of each convection. Comparison of average Nusselt number versus linear speed for the inner cylinder indicates the existence of the three different mechanisms which drive the convection in a rotation system. The convection pattern caused by rotation reduces the heat transfer efficiency. Our results in phase portraits also reveal the differences among different convection patterns.
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The reconstruction of gene regulatory networks from gene expression data has been the subject of intense research activity. A variety of models and methods have been developed to address different aspects of this important problem. However, these techniques are narrowly focused on particular biological and experimental platforms, and require experimental data that are typically unavailable and difficult to ascertain. The more recent availability of higher-throughput sequencing platforms, combined with more precise modes of genetic perturbation, presents an opportunity to formulate more robust and comprehensive approaches to gene network inference. Here, we propose a step-wise framework for identifying gene-gene regulatory interactions that expand from a known point of genetic or chemical perturbation using time series gene expression data. This novel approach sequentially identifies non-steady state genes post-perturbation and incorporates them into a growing series of low-complexity optimization problems. The governing ordinary differential equations of this model are rooted in the biophysics of stochastic molecular events that underlie gene regulation, delineating roles for both protein and RNA-mediated gene regulation. We show the successful application of our core algorithms for network inference using simulated and real datasets.