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Clin Radiol ; 74(5): 408.e19-408.e25, 2019 05.
Artigo em Inglês | MEDLINE | ID: mdl-30824110

RESUMO

AIM: To describe a new finding in fetuses with Chiari 2 malformations recognised at in utero (iu) magnetic resonance imaging (MRI), specifically T2 prolongation (high signal) in the cerebellar vermis. MATERIALS AND METHODS: This was a prospective observational study of iuMRI studies performed at two time points on 20 fetuses with Chiari 2 malformations and 10 control fetuses at the same time points. High T2 signal in the cerebellar vermis was noted and correlated with posterior fossa dimensions was assessed. RESULTS: High T2 signal in the cerebellar vermis was found in over half of the fetuses with a Chiari 2 malformation, but was not correlated with the degree of reduction in size of the bony posterior fossa. CONCLUSION: The present findings suggest that abnormal high T2 signal in the cerebellum is common in fetuses with Chiari 2 malformations and although the cause of the signal change is not known at present it may represent vasogenic oedema as a result of restricted venous drainage.


Assuntos
Malformação de Arnold-Chiari/patologia , Malformação de Arnold-Chiari/fisiopatologia , Vermis Cerebelar/fisiologia , Doenças Fetais/patologia , Doenças Fetais/fisiopatologia , Estudos de Casos e Controles , Feminino , Idade Gestacional , Humanos , Imageamento por Ressonância Magnética/métodos , Gravidez , Segundo Trimestre da Gravidez , Terceiro Trimestre da Gravidez , Diagnóstico Pré-Natal/métodos , Estudos Prospectivos
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