A Polish adaptation of the Self-Assessed Wisdom Scale (SAWS) in older adults. / Polska adaptacja Samoopisowej skali madrosci (SAWS). Wersja do badania osób starszych.

OBJECTIVES: The paper presents the results of work on the Polish adaptation of the Self-Assessed Wisdom Scale (SAWS). It presents the psychometric properties of the Polish version of the tool. METHODS: The research was quantitative in nature and it was carried out in a correlation scheme. The respondents completed a set of questionnaires. 880 subjects aged 60-80 years (M = 68.15; SD = 5.96) participated in the study. Apart from the SAWS six other psychological methods were used. The selection of measuring tools was purposeful. RESULTS: The final Polish version of the SAWS consists of 40 items (including 36 diagnostic ones) that make up 5 dimensions of wisdom: (1) "Critical Life Experience", (2) "Emotional Regulation", (3) "Reminiscence and Reflectiveness",(4) "Openness" and (5) "Humor". The reliability index for the entire scale (36 items) was α = 0.92 (very high). Reliability values (Cronbach's α) for individual scales vary from α = 0.60 to α = 0.84. The validity of the scale was evaluated by means of confirmatory analysis. CONCLUSIONS: The results are consistent with the original version of the scale, thus it has been indicated that the Polish version of the SAWS fulfils the psychometric requirements for psychological tests. The scale can be applied in scientific research.

An evaluation of the factor structure of the Self-Assessed Wisdom Scale (SAWS) and the creation of the SAWS-15 as a short measure for personal wisdom.

OBJECTIVES: Although wisdom is a desirable life span developmental goal, researchers have often lacked brief and reliable construct measures. We examined whether an abbreviated set of items could be empirically derived from the popular 40-item five-factor Self-Assessed Wisdom Scale (SAWS). DESIGN: Survey data from 709 respondents were randomly split into two and analyzed using confirmatory factor analysis (CFA). SETTING: The survey was conducted online in Australia. PARTICIPANTS: The total sample consisted of 709 participants (Mage = 35.67 years; age range = 15-92 years) of whom 22% were male, and 78% female. MEASUREMENT: The study analyzed the 40-item SAWS. RESULTS: Sample 1 showed the traditional five-factor structure for the 40-item SAWS did not fit the data. Exploratory factor analysis (EFA) on Sample 2 offered an alternative model based on a 15-item, five-factor solution with the latent variables Reminiscence/Reflection, Humor, Emotional Regulation, Experience, and Openness. This model, which replicates the factor structure of the original 40-item SAWS with a short form of 15 items, was then confirmed on Sample 1 using a CFA that produced acceptable fit and measurement invariance across age groups. CONCLUSIONS: We suggest the abbreviated SAWS-15 can be useful as a measure of individual differences in wisdom, and we highlight areas for future research.

Validating the Self-assessed Wisdom Scale (SAWS) in an Iranian Sample: Psychometric and Developmental Findings.

This study aimed to investigate the validity and factor structure of the Self-Assessed Wisdom Scale (SAWS; Webster in J Adult Dev 10:13-22, 2003) in an Iranian population. Participants (235 male, 340 female) were recruited in Tehran, Iran and ranged in age from 17 to 88 years. Cronbach alpha's for the subscales ranged from .63 to .81, and their inter-correlations ranged from .42 to .53. Exploratory factor analysis extracted 5 factors that were similar with the original structure. Confirmatory factor analysis supported 5-factor model of the SAWS. The SAWS's total and subscale scores positively correlated with two other measures of wisdom (indicating convergent validity). The SAWS correlated weakly with age. Women scored higher in the SAWS subscales of emotional regulation, reminiscence/reflectiveness, and humor, which accounted for a significant gender difference in total wisdom. Although the age differences are consistent with prior research, the gender differences are relatively novel. Overall, results indicate that the SAWS has excellent psychometric properties and can be used in cross-cultural work.

The Meaning of Temporal Balance: Does Meaning in Life Mediate the Relationship Between a Balanced Time Perspective and Mental Health?

The construct of a Balanced Time Perspective (BTP) predicts a variety of indices of mental health and well-being. We argue that one possible intermediate link between BTP and well-being may be an individual's sense of presence of meaning in life. Participants ranging in age from 19 to 88 years (N = 192) completed two measures of time perspective (Zimbardo Time Perspective Inventory [ZTPI] and the modified Balanced Time Perspective Scale [mBTPS]), mental health, personality, and meaning in life. Correlational results showed that a BTP, mental health, and meaning in life were positively interrelated. Hierarchical regression models showed that a BTP (as measured with the mBTPS) explained additional variance in mental health beyond demographic, personality, and ZTPI scores. Mediation analyses showed that meaning served as a significant indirect link between BTP and well-being.

Efficacy of verbenone and green leaf volatiles for protecting whitebark and limber pines from attack by mountain pine beetle (Coleoptera: Curculionidae: Scolytinae).

To develop safe and effective methods to protect whitebark pines, Pinus albicaulis Engelmann, and limber pines, Pinus flexilis James, from attack by mountain pine beetle, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae), we compared verbenone and verbenone plus green leaf volatiles (GLVs) for prevention of beetle attack. We used two strategies: area-wide protection where semiochemical-releasing flakes are dispersed over the forest floor, and individual tree tests where flakes are applied to tree trunks. The area-wide bioassays were conducted by applying verbenone- and GLV-releasing flakes without stickers to the forest floor on 0.81-ha plots dominated by whitebark pines in the State of Washington with four replicates. We conducted individual tree bioassays by applying the same formulations with stickers to whitebark and limber pines in Montana and Colorado, respectively. In all three situations, both verbenone-alone and verbenone plus GLVs significantly increased the proportion of trees escaping mass attack by beetles, but the two formulations were not significantly different from one another. Despite a lack of significance at a Bonferroni-adjusted α = 0.05, adding GLVs gave slightly greater absolute levels of tree protection in most cases. Monitoring traps placed in the area-wide treatments in Washington showed similar outcomes for numbers of beetles trapped: both treatments had significantly fewer beetles than controls, and they were not significantly different from one another. At peak flight, however, plots with GLVs combined with verbenone had roughly 40% fewer beetles than plots with verbenone alone. GLVs are considerably cheaper than verbenone, so tests of higher application rates may be warranted to achieve enhanced tree protection at reasonable cost.

Time to flourish: the relationship of temporal perspective to well-being and wisdom across adulthood.

OBJECTIVES: Despite the centrality of time to the aging process, the well-being consequences of different temporal orientations for optimal aging are poorly understood. We investigate one underexamined area of temporal orientation, namely a balanced time perspective, in a large, lifespan sample from the Netherlands. METHOD: Participants consisted of 512 Dutch adults ranging in age from 17 to 92 years (Mage = 46.46, SD = 21.37), including 186 male and 326 females. Participants completed a measure of balanced time perspective, mental health, and wisdom. RESULTS: RESULTS indicated that a balanced time perspective uniquely predicted both mental health and wisdom even after controlling for demographic, physical health, and personality variables. Younger adults tended to be more future-oriented relative to older adults while older adults tended to be more past-oriented relative to younger adults. Further, both midlife and younger adults were more likely to have a balanced time perspective relative to older adults. CONCLUSION: A balanced time perspective is associated with higher well-being and wisdom across the adult age span.

Wisdom and mental health across the lifespan.

OBJECTIVES: The relationships between wisdom and age and between wisdom and mental health are complex with empirical results often inconsistent. We used a lifespan sample and broad, psychometrically sound measures of wisdom and mental health to test for possible age trends in wisdom and its subcomponents and the relationship between wisdom and hedonic and eudaimonic aspects of well-being. METHOD: Participants included 512 Dutch adults ranging in age from 17 to 92 (M age = 46.46, SD = 21.37), including 186 men and 326 women. Participants completed measures of wisdom, physical health, mental health, and personality. RESULTS: Significant quadratic trends indicated that middle-aged adults scored higher on wisdom than younger and older adults. Investigation of wisdom subcomponents illustrated that a complex pattern of increases and decreases in different aspects of wisdom helped account for these age findings. Bivariate correlations showed the expected positive association between wisdom and mental health. Hierarchic regression analyses indicated that the positive association between wisdom and mental health remained significant after accounting for demographic variables (i.e., sex, age, education) and personality traits (i.e., neuroticism, extraversion, and openness to experience). DISCUSSION: Age trends in the components of wisdom (older adults higher in life experience but lower in openness relative to younger and middle-aged adults) help explain the curvilinear pattern showing an advantage in wisdom for middle-aged adults. The greater association between wisdom and eudaimonic well-being suggests that wise persons enhance mental health by pursuing meaningful activities.

A Balanced Time Perspective in Adulthood: Well-being and Developmental Effects.

This article presents a study that directly replicated the recently developed Balanced Time Perspective Scale (BTPS; J.D. Webster, 2011 ) and included middle-aged and older adults. Participants included 90 younger, 69 middle-aged, and 69 older adults who completed the BTPS and a measure of life satisfaction and happiness. A factor analysis replicated original findings with separate subscales for a past orientation and a future orientation obtaining simple structure (alphas = .94 and .95 respectively). A balanced time perspective predicted higher scores on both measures of well-being replicating the original J.D. Webster ( 2011 ) findings. A chi-square analysis indicated, as predicted, that the percentage of younger adults tended to be higher in the future-focused category, and the percentage of older adults tended to be higher in the past-focused category. Implications of a balanced time perspective on mental health over the life course are discussed.

Development of a high-throughput cell-based assay for identification of IL-17 inhibitors.

Human interleukin 17 (IL-17) is a proinflammatory cytokine derived mainly from activated T cells. Extensive evidence points to a significant role of IL-17 in many autoimmune and infectious diseases, as well as tumorigenesis and transplant rejection, and suggests that targeting IL-17 could be a promising therapeutic strategy. Robust cell-based assays would thus be essential for lead identification and the optimization of therapeutic candidates. Herein, we report a well-characterized two-step assay, consisting of (a) in vitro activation and stimulation of CD4(+) T lymphocytes by a defined complex of antibodies and cytokines, leading to T helper 17 (Th17) cell differentiation and IL-17 production, and (b) IL-17 quantification in cell supernatants using a homogeneous time-resolved fluorescence (HTRF) assay. The system was optimized for and shown to be reliable in high-throughput compatible 96- and 384-well plate formats. The assay is robust (Z' > 0.5) and simple to perform, yields a stable response, and allows for sufficient discrimination of positive (IL-17-producing cells) and negative controls (uninduced cells). The assay was validated by performing dose-response testing of rapamycin and cyclosporine A, which had previously been reported to inhibit IL-17, and determining, for the first time, their in vitro potencies (IC(50)s of 80 ± 23 pM and 223 ± 52 nM, respectively). Also, IKK 16, a selective small-molecule inhibitor of IκB kinase, was found to inhibit IL-17 production, with an IC(50) of 315 ± 79 nM.

The push-pull tactic for mitigation of mountain pine beetle (Coleoptera: Curculionidae) damage in lodgepole and whitebark pines.

In an attempt to improve semiochemical-based treatments for protecting forest stands from bark beetle attack, we compared push-pull versus push-only tactics for protecting lodgepole pine (Pinus contorta Douglas ex Loudon) and whitebark pine (Pinus albicaulis Engelm.) stands from attack by mountain pine beetle (Dendroctonus ponderosae Hopkins) in two studies. The first was conducted on replicated 4.04-ha plots in lodgepole pine stands (California, 2008) and the second on 0.81-ha plots in whitebark pine stands (Washington, 2010). In both studies, D. ponderosae population levels were moderate to severe. The treatments were 1) push-only (D. ponderosae antiaggregant semiochemicals alone); 2) push-pull (D. ponderosae antiaggregants plus perimeter traps placed at regular intervals, baited with four-component D. ponderosae aggregation pheromone); and 3) untreated controls. We installed monitoring traps baited with two-component D. ponderosae lures inside each plot to assess effect of treatments on beetle flight. In California, fewer beetles were collected in push-pull treated plots than in control plots, but push-only did not have a significant effect on trap catch. Both treatments significantly reduced the rate of mass and strip attacks by D. ponderosae, but the difference in attack rates between push-pull and push-only was not significant. In Washington, both push-pull and push-only treatments significantly reduced numbers of beetles caught in traps. Differences between attack rates in treated and control plots in Washington were not significant, but the push-only treatment reduced attack rates by 30% compared with both the control and push-pull treatment. We conclude that, at these spatial scales and beetle densities, push-only may be preferable for mitigating D. ponderosae attack because it is much less expensive, simpler, and adding trap-out does not appear to improve efficacy.

Comparing the psychometric properties of two measures of wisdom: predicting forgiveness and psychological well-being with the Self-Assessed Wisdom Scale (SAWS) and the Three-Dimensional Wisdom Scale (3D-WS).

Two recently developed scales of wisdom were compared on their abilities to have their dimensional structure replicated and to predict relevant personality (i.e., forgiveness) and life satisfaction (i.e., psychological well-being) variables. One hundred and seventy-six primarily (71%) Australian participants ranging in age from 18 to 68 years (M = 36.60, SD = 12.07) completed an online survey of the Self-Assessed Wisdom Scale (SAWS; Webster, 2003, Journal of Adult Development, 10, 13-22; 2007, International Journal of Aging and Human Development, 65, 163-183), the Three-Dimensional Wisdom Scale (3D-WS; Ardelt, 2003, Journal of Gerontology: Psychological Sciences, 52B, 15-27), the Heartland Forgiveness Scale (Thompson et al., 2005, Journal of Personality, 73, 313-360), Ryff's (1989, Journal of Personality and Social Psychology, 57, 1069-1081) measure of psychological well-being (PWB), and a measure of social desirability (BIDR; Paulhus, 1984, Journal of Personality and Social Psychology, 46, 598-609). Results indicated that the dimensional structure of the SAWS, but not the 3D-WS, replicated, and the 3D-WS, but not the SAWS, was contaminated by a social desirability response bias. Both scales predicted equally well PWB and forgiveness in predicted directions. Implications for future use of both scales are discussed.

Factorial structure and psychometric properties of the reminiscence functions scale.

OBJECTIVES: This study reports on the psychometric properties and the factorial structure of the Reminiscence Functions Scale (RFS), a 43-item self-report instrument used to assess the frequencies of reminiscence for distinct functions. METHOD: The factorial validity (exploratory factor analysis, n = 453; confirmatory factor analysis, n = 456), the invariance of factorial structure across gender (males = 228; females = 240), and psychometric properties were examined. RESULTS: They support an eight-factor structure similar to the original one, yet question the value of a few of the items. Cronbach's alphas for the various subscales ranged from 0.76 to 0.87. Test-retest reliability ranged from r = 0.48-0.63. CONCLUSION: The RFS is confirmed as a psychometrically sound instrument for use in research on the functions of reminiscence with samples of older adults.

Measuring the character strength of wisdom.

This study examined the psychosocial correlates and psychometric properties of the Self-Assessed Wisdom Scale (SAWS). Seventy-three men and 98 women ranging in age from 17-92 years (Mean age = 42.77) completed an expanded, 40-item version of the SAWS, the Loyola Generativity Scale, and the Experiences in Close Relationships Scale. A new definition of wisdom is provided which is operationalized with the SAWS. Results indicated that the SAWS has excellent reliability (test-retest = .838; Cronbach's Alpha = .904). Exploratory and Confirmatory Factor analyses confirmed the five hypothesized dimensions of wisdom and the total SAWS score correlated in predicted directions with generativity (r(169) = .448; p < .01) and attachment avoidance (r(169) = -.239, p < .01) demonstrating construct validity.

Reminiscence and vivid personal memories across adulthood.

This study examined reminiscence functions and vivid (i.e., landmark) personal memories in nine samples ranging from the teens to the nineties. Participants (n = 198) ranging in age from 18-95 years completed the Reminiscence Functions Scale (Webster, 1997) and described a vivid personal memory which was subsequently rated for frequency of recall, emotional valence, time of occurrence, impact, and thematic content. Reminiscence results showed that older adults tend to reminiscence more for social functions while younger adults tend to reminisce more for self functions. Older adults reported vivid memories that were less intimate and less negative although adults of all ages showed the "reminiscence bump." Significant relationships were also obtained between the content of vivid memories described and the patterns of general reminiscence behaviors.

New scores for the Category Test: measures of interference for subtests 5 and 6.

The Category Test is a well-known neuropsychological instrument used to assess concept formation and higher executive abilities. The present study investigated the utility of additional scores for the Category Test. We used principles developed in cognitive psychology to create several new measures for subtests 5 and 6 of this test. These scores were primarily designed to be sensitive to interference effects of learning decision rules from subtest 2, subtest 3, and subtest 4. The new scores as well as the total error scores from subtests 5 and 6 were used to discriminate subjects with documented brain injury from subjects who were neurologically normal based on neuroimaging and neurologic evaluation. The Category Test was given following Reitan's (1979) instructions, with the exception that no additional prompting was given to participants who struggled early with the test in order to reduce the "executive" guidance of the examiner. Because any "interference" from earlier subtests on performance of subtest 5 and subtest 6 should be related to mastery of these earlier subtests, the normal group was matched to the brain-impaired group on which subtest(s) they learned. This resulted in four learning groups: (a) learned subtests 3 and 4; (b) learned subtest 4 but not 3; (c) learned subtest 3 but not 4; and (d) failed to learn either subtest. ANOVA analyses revealed that the three measures of interference were significantly greater in the brain-damaged group than in the normal controls. Also, specific interference measures were related to specific prior subtest mastery, thus providing support for a proactive interference effect. In addition, we have evidence that our new measures may be selectively sensitive to frontal system dysfunction.

The reminiscence circumplex and autobiographical memory functions.

This study investigated the potential of a circumplex model to represent the functions of both reminiscence and autobiographical memory. Participants from four pre-existing data bases (i.e., Culley, LaVoie, & Gfeller, 2001; Webster, 1997, 2002; Webster & McCall, 1999) were combined, resulting in a total of 985 participants ranging in age from 17 to 96 (M age = 36.63 years). A total of 392 men (39.8%) and 591 women (60.1%), with two persons not reporting their gender, completed the Reminiscence Functions Scale (RFS) as part of the original four studies. The eight RFS factors were submitted to second-order factor analysis resulting in two orthogonal dimensions (self versus social and reactive/loss-oriented versus proactive/growth-oriented) accounting for 79.57% of the variance. Further, multidimensional scaling indicated that the original eight factors could be arranged in a circular fashion such that more closely related (i.e., more highly correlated) factors were placed closer together while factors less highly related were placed further apart. Advantages of a circumplex perspective for future theory and model development are illustrated.

Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types.

Using microarray technology, we analyzed 12,000 genes for regulation by TNF-alpha and the synthetic glucocorticoid, dexamethasone, in the human lung epithelial cell line, A549. Only one gene was induced by both agents, the cellular inhibitor of apoptosis 2 (c-IAP2), which was induced 17-fold and 5-fold by TNF-alpha at 2 h and 24 h, respectively, and increased 14-fold and 9-fold by dexamethasone at 2 h and 24 h, respectively. The combination of the two agents together led to an additive increase (34-fold) at 2 h and a more than additive effect (36-fold) at 24 h. The human c-IAP2 promoter contains two nuclear factor (NF)-kappaB sites that have been shown to be required for transcriptional activation by TNF-alpha. To test whether glucocorticoids regulate the c-IAP2 gene at the level of the promoter, a reporter vector containing 947 bases upstream of the start site of transcription of the human c-IAP2 promoter was linked to luciferase [IAP(-947-+54)-LUC] and transfected into A549 cells. Dexamethasone and TNF-alpha each induced reporter activity, whereas the combination of the two agents led to greater induction of luciferase than either one alone. Truncation of the promoter region containing a putative glucocorticoid response element (GRE) at -515 [IAP(-395-+54)-LUC] or mutation of the GRE in the context of the natural promoter [IAP(-947-+54mutGRE)-LUC] resulted in a loss of dexamethasone-mediated induction of reporter activity. Although the functional NF-kappaB sites were retained in the truncated and mutant c-IAP2 promoter constructs, dexamethasone did not inhibit the TNF-alpha induction of luciferase activity, indicating that GR repression through the NF-kappaB sites did not occur. Regulation of the c-IAP2 gene is therefore unique, as GR and NF-kappaB signaling pathways are usually mutually antagonistic, not cooperative. Treatment of A549 cells with TNF-alpha and/or dexamethasone had no effect on cell death, but the two agents were able to inhibit interferon-gamma/anti-FAS antibody-mediated apoptosis. In human glioblastoma A172 cells, TNF-alpha and dexamethasone together elicited a greater than additive increase in c-IAP2 mRNA levels and also inhibited anti-FAS antibody-mediated A172 cell apoptosis. In contrast, in human CEM-C7 leukemic T cells, whereas TNF-alpha and dexamethasone treatment also led to an increase in c-IAP2 mRNA, the two agents were able to induce apoptosis on their own. However, TNF-alpha and dexamethasone were also able to blunt anti-FAS-induced apoptosis in the T cells. These data indicate that the induction of the antiapoptotic protein, c-IAP2, by glucocorticoids and TNF-alpha correlates with the ability of these agents to inhibit apoptosis in a variety of cell types.

Adult attachment and preparing to provide care for older relatives.

A normative developmental task of middle-aged adults is to consider older family members' care needs. Preparing for future caregiving responsibilities may be an important way to prevent excessive stress responses when the caregiver role is taken on. The present study investigates the extent to which attachment style and dimensions of attachment insecurity predict whether middle-generation adults prepare for possible future caregiving responsibilities, feel prepared for these responsibilities and are satisfied with their preparation activities. Middle-generation parents of undergraduate students (N = 141) were sent questionnaires assessing adult attachment style, attachment insecurity, preparation for future care activities, feelings of preparedness, and satisfaction with preparation. Results suggest that secure attachment style and lower attachment insecurity had limited associations with preparation activities, whereas the associations with feelings of preparedness were more robust. Moreover, attachment variables predict feelings of preparedness even after controlling for the influence of actual preparation behaviors. Separate analyses for individuals already providing care vs. those not yet providing care suggest that secure attachment may be more important in predicting preparation activities for individuals not yet providing care.