RESUMO
These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group of European experts following a systematic review of the current literature, an expert conference held in Toulouse in 2016, and a consensus on the discussions. These guidelines summarize evidence and expert-based recommendations and intend to help clinicians with the management of these rare and often complex diseases. These guidelines comprise two sections. This is part two, covering the management of complications and the particularities of some forms of congenital ichthyosis.
Assuntos
Consenso , Dermatologia/normas , Eritrodermia Ictiosiforme Congênita/terapia , Ictiose/terapia , Doenças do Prematuro/terapia , Dermatologia/métodos , Europa (Continente) , Humanos , Eritrodermia Ictiosiforme Congênita/complicações , Ictiose/complicaçõesRESUMO
These guidelines for the management of congenital ichthyoses have been developed by a multidisciplinary group of European experts following a systematic review of the current literature, an expert conference held in Toulouse in 2016 and a consensus on the discussions. They summarize evidence and expert-based recommendations and are intended to help clinicians with the management of these rare and often complex diseases. These guidelines comprise two sections. This is part one, covering topical therapies, systemic therapies, psychosocial management, communicating the diagnosis and genetic counselling.
Assuntos
Terapia Comportamental/normas , Consenso , Fármacos Dermatológicos/uso terapêutico , Dermatologia/normas , Eritrodermia Ictiosiforme Congênita/terapia , Administração Oral , Administração Tópica , Terapia Comportamental/métodos , Dermatologia/métodos , Europa (Continente) , Aconselhamento Genético/normas , Humanos , Eritrodermia Ictiosiforme Congênita/diagnóstico , Eritrodermia Ictiosiforme Congênita/psicologia , Qualidade de Vida , Apoio Social , Revisões Sistemáticas como AssuntoRESUMO
BACKGROUND: Knowledge about frailty among patients seen by general practitioners (GP) is currently limited. PATIENTS AND METHODS: Frailty assessment by the criteria of Fried and additional documentation was performed at a GP's office. RESULTS: Out of 119 participating patients, 14.3% were classified as frail, 52.1% as prefrail, and 33.6% as not frail. Frailty was associated with comorbidity, the number of drugs prescribed, depressive symptoms, cognitive function, and frequency of falls. CONCLUSION: The prevalence of frailty is high among the cohort of elderly persons seen by a GP. Routine frailty assessment will help to direct preventive and therapeutic interventions.
Assuntos
Clínicos Gerais/estatística & dados numéricos , Avaliação Geriátrica/estatística & dados numéricos , Debilidade Muscular/diagnóstico , Debilidade Muscular/epidemiologia , Padrões de Prática Médica/estatística & dados numéricos , Idoso , Idoso de 80 Anos ou mais , Feminino , Alemanha/epidemiologia , Humanos , Masculino , Projetos Piloto , Prevalência , SíndromeRESUMO
One month after a successful angioplasty, one of our patients developed a new aneurysm in the right coronary artery (RCA). The aneurysm was characterized as a pseudoaneurysm by the use of intravascular ultrasound (IVUS). A stenosis that was not well seen by angiography was better depicted by IVUS. Both the pseudoaneurysm and the stenosis were successfully treated with a second angioplasty and stenting with a covered stent. Delayed development of pseudoaneurysms after dissection is an uncommon, but possible complication after angioplasty. In this case IVUS was useful for accurate characterization of the aneurysm. The use of covered stents may become a clinically useful method for treating coronary pseudoaneurysms.
Assuntos
Falso Aneurisma/etiologia , Angioplastia Coronária com Balão/efeitos adversos , Aneurisma Coronário/etiologia , Idoso , Falso Aneurisma/diagnóstico por imagem , Aneurisma Coronário/diagnóstico por imagem , Angiografia Coronária , Humanos , Masculino , Stents , Fatores de Tempo , Ultrassonografia de IntervençãoAssuntos
Doença das Coronárias/cirurgia , Anomalias dos Vasos Coronários/cirurgia , Átrios do Coração/anormalidades , Angiografia Coronária , Doença das Coronárias/diagnóstico por imagem , Anomalias dos Vasos Coronários/diagnóstico por imagem , Átrios do Coração/diagnóstico por imagem , Átrios do Coração/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Técnicas de SuturaRESUMO
1. The gonadospecific DIA3 types were traceable for 4 weeks, in some cases for 6 weeks. 2. EsD polymorphism was not demonstrable by starch gel electrophoresis in sperm, not even in sperm lysates. 3. EsA patterns showed only non-reproducible differences. 4. Because of their low concentrations, salivary esterase cannot cause errors when mixed stains are examined.
