Syngas Production from CO2 and H2O via Solid-Oxide Electrolyzer Cells: Fundamentals, Materials, Degradation, Operating Conditions, and Applications.

Highly efficient coelectrolysis of CO2/H2O into syngas (a mixture of CO/H2), and subsequent syngas conversion to fuels and value-added chemicals, is one of the most promising alternatives to reach the corner of zero carbon strategy and renewable electricity storage. This research reviews the current state-of-the-art advancements in the coelectrolysis of CO2/H2O in solid oxide electrolyzer cells (SOECs) to produce the important syngas intermediate. The overviews of the latest research on the operating principles and thermodynamic and kinetic models are included for both oxygen-ion- and proton-conducting SOECs. The advanced materials that have recently been developed for both types of SOECs are summarized. It later elucidates the necessity and possibility of regulating the syngas ratios (H2:CO) via changing the operating conditions, including temperature, inlet gas composition, flow rate, applied voltage or current, and pressure. In addition, the sustainability and widespread application of SOEC technology for the conversion of syngas is highlighted. Finally, the challenges and the future research directions in this field are addressed. This review will appeal to scientists working on renewable-energy-conversion technologies, CO2 utilization, and SOEC applications. The implementation of the technologies introduced in this review offers solutions to climate change and renewable-power-storage problems.

Erratum: Ascorbic acid induced HepG2 cells' apoptosis via intracellular reductive stress: Erratum.

[This corrects the article DOI: 10.7150/thno.33783.].

A differential study on oxidized/reduced ascorbic acid induced tumor cells' apoptosis under hypoxia.

The anticancer mechanism for reduced/oxidized ascorbic acid (AA/DHA) is of great significance for clinical cancer therapies. A pH controlled fluorescent nanocarrier was designed to targetably deliver AA and DHA into tumor cells for investigating their function in inducing intracellular apoptosis pathways. A fluorescent silicon nanoparticle with polymer coating serves as the pH controlled nanocarrier to deliver AA or DHA into HepG2 and B16-F10 cells for studying their biological functions. The intracellular apoptotic pathway was monitored through the Caspase-3 nanoprobe, while the changes of signal molecules H2O2 and NAD(P)H in the redox homeostasis system were monitored through the corresponding fluorescent probes. Under hypoxic conditions, AA can scavenge H2O2 in tumor cells and promote NAD(P)H accumulation, but DHA promotes the production of both H2O2 and NAD(P)H, indicating that the molecular mechanisms for inducing cancer cells' apoptosis are significantly different. AA leads to reductive stress by promoting the accumulation of NAD(P)H in tumor cells, but DHA enhances oxidative stress by increasing the H2O2 concentration in cells.

Adsorption of low-concentration VOCs on various adsorbents: Correlating partition coefficient with surface energy of adsorbent.

Accurately evaluating the adsorption properties of various adsorbents by some parameter is of great significance to select an appropriate adsorbent and remove volatile organic compounds (VOCs) efficiently. In this study, we successfully found a new parameter as a common standard in selecting adsorbents. Six classical adsorbents containing three carbon materials and three porous polymeric resins were used, and their surface energy (γst) and corresponding gas-solid partition coefficients (K) of eleven VOCs were measured by inverse gas chromatography (IGC) at three different column temperatures of 343 K(or 353 K), 373 K and 403 K. Then, these values at 303 K were calculated according to the linear relationship between lnK and 1/T. It was found that surface energy was significantly correlated with K values for a specific VOC, and could be used as a common standard to well evaluate the adsorption properties of various adsorbents. Furthermore, we employed it to develop a model for predicting the adsorption properties of low-concentration VOCs on various adsorbents at 303 K. The developed model exhibited an excellent predictive ability by external validation. Moreover, the model showed wide applicability and predicted the lnK values of VOCs at 373 K and 403 K in R2 of 0.910 and 0.889.

Predicting adsorption coefficients of VOCs using polyparameter linear free energy relationship based on the evaluation of dispersive and specific interactions.

Predicting adsorption of volatile organic compounds (VOCs) on activated carbons is of major importance to understand activated carbons' adsorption properties and explore their potential applications. In this study, adsorption of 38 VOCs on a commercial granular activated carbon (GAC) was examined using inverse gas chromatography (IGC) at infinite dilution, and the adsorption coefficients (K), dispersive and specific components of adsorption free energy were calculated. We found that the dispersive interaction was well described by adsorbate's molar polarizability (P), and the specific interactions well by dipolarity/polarizability (S), hydrogen-bond acidity (A) and hydrogen-bond basicity (B). Based on the result, a polyparameter linear free energy relationship (PP-LFER) was established: logK = (0.96 ±â€¯0.23) S + (2.23 ± 0.34) A + (0.84 ± 0.25) B + (0.69 ± 0.050) P + (0.13 ± 0.35); (n = 38, R2 = 0.859, root mean square error (RMSE) = 0.25), which exhibited a more accurate prediction compared to the classical PP-LFER (E, S, A, B and L as descriptors, R2 = 0.765, RMSE = 0.33). Moreover, it overcame the drawbacks of indistinguishable dispersive interaction and unavailable relative contribution of each interaction for classical PP-LFER in explaining adsorption mechanism. As suggested by the developed model, the dispersive interaction was the dominant contribution to the adsorption of VOCs on GAC (42-100%), following by dipole-type interactions (0-30%) and hydrogen bonding (hydrogen-bond acidity 0-32%, hydrogen-bond basicity 0-11%). Additionally, it also accurately predicted the K values of VOCs on other three activated carbons.

Ascorbic acid induced HepG2 cells' apoptosis via intracellular reductive stress.

Goals: Destruction of the redox balance in tumor cells is of great significance for triggering their apoptosis in clinical applications. We designed a pH sensitive multifunctional drug nanocarrier with controllable release of ascorbic acid under hypoxic environment to induce tumor cells' apoptosis via enhancing reductive stress, thereby dealing minimum damage to normal tissues. Methods: A core-shell nanostructure of CdTe quantum dots with mesoporous silica coating was developed and functionalized with poly(2-vinylpyridine)-polyethylene glycol-folic acid, which achieves cancer cells' targeting delivery and reversibly pH controlled release of ascorbic acid both in vitro and in vivo. Results: The result demonstrated that ascorbic acid can indeed lead liver cancer cells' death with the increase of nicotinamide adenine dinucleotide phosphate, while normal cells not being affected. The molecular mechanism of apoptosis induced by ascorbic acid was firstly elucidated at cellular levels, and further confirmed via in vivo investigations. Conclusion: For the first time we proposed the concept for applying reductive stress into cancer treatments, which brings great advantage of toxicity free and less damage to normal tissues. In general, this technique has taken an important step in the development of a targeted tumor treatment system, providing perspectives for the design of medicines via reductive stress, and offers new insights into future clinical mild-therapies.

Dicyanoisophorone-Based Near-Infrared-Emission Fluorescent Probe for Detecting NAD(P)H in Living Cells and in Vivo.

NADH and NADPH are ubiquitous coenzymes in all living cells that play vital roles in numerous redox reactions in cellular energy metabolism. To accurately detect the distribution and dynamic changes of NAD(P)H under physiological conditions is essential for understanding their biological functions and pathological roles. In this work, we developed a near-infrared (NIR)-emission fluorescent small-molecule probe (DCI-MQ) composed of a dicyanoisophorone chromophore conjugated to a quinolinium moiety for in vivo NAD(P)H detection. DCI-MQ has the advantages of high water solubility, a rapid response, extraordinary selectivity, great sensitivity (a detection limit of 12 nM), low cytotoxicity, and NIR emission (660 nm) in response to NAD(P)H. Moreover, the probe DCI-MQ was successfully applied for the detection and imaging of endogenous NAD(P)H in both living cells and tumor-bearing mice, which provides an effective tool for the study of NAD(P)H-related physiological and pathological processes.

Generation of femtosecond optical vortex pulse in fiber based on an acoustically induced fiber grating.

We proposed a method for generation of a femtosecond optical vortex pulse in a two-mode fiber based on an acoustically induced fiber grating (AIFG) driven by a radio frequency source. Theoretical analysis and experimental results demonstrated that the left- and right-handed circular polarization fundamental modes of the femtosecond optical pulse could be converted to the linearly polarized ±1-order optical vortex modes through the AIFG with the mode conversion efficiency of ∼95%. The off-axial interference experiment and the polarization angle-dependent intensity examination were performed to verify the topological charge and the polarization state of the femtosecond optical vortex, respectively.

Generation of cylindrical vector beams and optical vortex by two acoustically induced fiber gratings with orthogonal vibration directions.

Mode coupling from the fundamental vector mode (HE11x) to the cylindrical vector beams (CVBs) and optical vortex beams (OVBs) of a few-mode fiber excited by two acoustic flexural waves with orthogonal perturbations is achieved by using a composite acoustic transducer. The HE11x mode is converted to TM01 and TE01 modes, which have radial and azimuthal polarizations, by using the lowest-order acoustic flexural modes of F11x and F11y, respectively. Furthermore, HE11x mode can also be converted to the ± 1-order OVBs of HE21even±iHE21odd through the combined acoustic modes of F11x±iF11y. This technique provides a useful way of generating CVBs and OVBs in optical fiber with conveniently electrically-controlled mode conversion characteristics.

High-order optical vortex generation in a few-mode fiber via cascaded acoustically driven vector mode conversion.

We propose a method to generate the high-order optical vortex in a few-mode fiber via cascaded acoustically driven vector mode conversion. Theoretical analysis showed that the vector mode conversion induced by the acoustically induced fiber grating (AIFG) could occur between two HE modes with adjacent azimuthal numbers. In the experiment conducted at 532 nm, two AIFGs were simultaneously induced in the same segment of the fiber by a radio frequency source containing two different frequency components. One AIFG was used to convert the left- and right-handed circular polarization fundamental modes to the ±1-order vortex modes, which were then further converted to the ±2-order vortex modes by the other AIFG. The topological charges of the vortex modes were verified using both coaxial and off-axial interference methods, showing typical signature patterns of spiral forms and forklike fringes, respectively.

Optical vortex generation with wavelength tunability based on an acoustically-induced fiber grating.

We presented a method to actualize the optical vortex generation with wavelength tunability via an acoustically-induced fiber grating (AIFG) driven by a radio frequency source. The circular polarization fundamental mode could be converted to the first-order optical vortex through the AIFG, and its topological charges were verified by the spiral pattern of coaxial interference between the first-order optical vortex and a Gaussian-reference beam. A spectral tuning range from 1540 nm to 1560 nm was demonstrated with a wavelength tunability slope of 4.65 nm/kHz. The mode conversion efficiency was 95% within the whole tuning spectral range.

Cylindrical vector beam generation in fiber with mode selectivity and wavelength tunability over broadband by acoustic flexural wave.

Theoretical analysis and experimental demonstration are presented for the generation of cylindrical vector beams (CVBs) via mode conversion in fiber from HE11 mode to TM01 and TE01 modes, which have radial and azimuthal polarizations, respectively. Intermodal coupling is caused by an acoustic flexural wave applied on the fiber, whereas polarization control is necessary for the mode conversion, i.e. HE11x→TM01 and HE11y→TE01 for acoustic vibration along the x-axis. The frequency of the RF driving signal for actuating the acoustic wave is determined by the phase matching condition that the period of acoustic wave equals the beatlength of two coupled modes. With phase matching condition tunability, this approach can be used to generate different types of CVBs at the same wavelength over a broadband. Experimental demonstration was done in the visible and communication bands.