Development and validation of the ADHD Symptom and Side Effect Tracking - Baseline Scale (ASSET-BS): a novel short screening measure for ADHD in clinical populations.

OBJECTIVE: The aim was to develop and test a novel screen of adult ADHD, with a specific focus on clinical use. We designed a series of three studies to accomplish this aim. METHOD: Study One (n = 155) and Study Two (n = 591) collected data via surveys to conduct exploratory and confirmatory factor analyses, respectively. Study Three analyzed the scale's psychometrics in a clinical sample (n = 151). RESULTS: Study One and Study Two identified a 10-item scale with a two-factor structure. Study Three found good discriminant validity, sensitivity = 80.0%, specificity = 80.2%, and convergent validity with both the Brown Executive Function/Attention Scales, r (131) = .76, p < .001, and the Conner's Adult ADHD Rating Scales r (131) = .71, p < .001. CONCLUSION: The scale demonstrated effectiveness in screening for ADHD in a psychiatric outpatient population. Its results may be used to identify patients that may benefit from thorough ADHD diagnostic procedures.

Low Perinatal Androgens Predict Recalled Childhood Gender Nonconformity in Men.

The contributions of gonadal hormones to the development of human behavioral sex differences are subjects of intense scientific and social interest. Isolated gonadotropin-releasing-hormone deficiency (IGD) is a rare endocrine disorder that can reveal a possible role of early gonadal hormones. IGD is characterized by low or absent gonadal hormone production after the first trimester of gestation, but external genitalia and hence gender of rearing are concordant with chromosomal and gonadal sex. We investigated recalled childhood gender nonconformity in men (n = 65) and women (n = 32) with IGD and typically developing men (n = 463) and women (n = 1,207). Men with IGD showed elevated childhood gender nonconformity, particularly if they also reported undescended testes at birth, a marker of low perinatal androgens. Women with IGD did not differ from typically developing women. These results indicate that early androgen exposure after the first trimester contributes to male-typical gender-role behaviors in childhood.

Evidence that perinatal ovarian hormones promote women's sexual attraction to men.

Ovarian estrogens may influence the development of the human brain and behavior, but there are few opportunities to test this possibility. Isolated GnRH deficiency (IGD) is a rare endocrine disorder that could provide evidence for the role of estrogens in organizing sexually differentiated phenotypes: Unlike typical development, development in individuals with IGD is characterized by low or absent gonadal hormone production after the first trimester of gestation. Because external genitalia develop in the first trimester, external appearance is nevertheless concordant with gonadal sex in people with IGD. We therefore investigated the effects of gonadal hormones on sexual orientation by comparing participants with IGD (n = 97) to controls (n = 1670). Women with IGD reported lower male-attraction compared with typically developing women. In contrast, no consistent sexuality differences between IGD and typically developing men were evident. Ovarian hormones after the first trimester appear to influence female-typical dimensions of sexual orientation.

Pubertal timing predicts adult psychosexuality: Evidence from typically developing adults and adults with isolated GnRH deficiency.

Evidence suggests that psychosexuality in humans is modulated by both organizational effects of prenatal and peripubertal sex steroid hormones, and by activational effects of circulating hormones in adulthood. Experimental work in male rodents indicates that sensitivity to androgen-driven organization of sexual motivation decreases across the pubertal window, such that earlier puberty leads to greater sex-typicality. We test this hypothesis in typically developing men (n = 231) and women (n = 648), and in men (n = 72) and women (n = 32) with isolated GnRH deficiency (IGD), in whom the precise timing of peripubertal hormone exposure can be ascertained via the age at which hormone replacement therapy (HRT) was initiated. Psychosexuality was measured with the Sexual Desire Inventory-2 (SDI-2) and Sociosexual Orientation Inventory-Revised (SOI-R). In both sexes, earlier recalled absolute pubertal timing predicted higher psychosexuality in adulthood, although the magnitude of these associations varied with psychosexuality type and group (i.e., typically developing and IGD). Results were robust when controlling for circulating steroid hormones in typically developing participants. Age of initiation of HRT in men with IGD negatively predicted SOI-R. We discuss the clinical implications of our findings for conditions in which pubertal timing is medically altered.

Sexual Motivation and Satisfaction Among Consensually Non-Monogamous and Monogamous Individuals.

BACKGROUND: Previous research has found differences in sexual motives and, separately, sexual satisfaction in consensually non-monogamous (CNM) and monogamous individuals and that these constructs are related to relationship outcomes (eg, relationship quality). AIMS: The present study sought to refine and expand on previous research by (i) using a more common, validated measure of sexual motives, (ii) measuring sexual satisfaction with multiple partners within CNM relationships, and (iii) examining how sexual motives are related to sexual satisfaction in CNM relationships. METHODS: Participants were recruited from a university and using online forums that CNM individuals frequently use (eg, reddit, Facebook). Individuals recruited included those in non-exclusive relationships with one partner ("non-exclusive single-partner;" n = 40), those in non-exclusive relationships with more than one partner ("non-exclusive multipartner;" n = 87), and monogamous individuals (n = 322). Data were analyzed using multivariate analysis of variance and hierarchical multiple regressions. OUTCOMES: The main outcome measures of this study are scores on the Why Humans Have Sex Scale and the New Scale for Sexual Satisfaction. RESULTS: Non-exclusive multipartner participants were more motivated to have sex for physical motivations compared with monogamous participants. Although there were no significant differences in sexual satisfaction when comparing monogamous with non-exclusive multipartner participant's secondary and primary partners, unique patterns of sexual motivations were associated with sexual satisfaction based on relationship configuration. CLINICAL TRANSLATION: Understanding the unique sexual motives associated with sexual satisfaction in various relationship configurations may help improve clinical approaches to couples counseling for both CNM and non-CNM populations. STRENGTHS AND LIMITATIONS: Data were collected from CNM participants in a variety of relationship configurations and provide analyses comparing primary and secondary partners. However, these results are limited by a small sample of CNM participants who were intentionally recruited from self-identified CNM e-forums. CONCLUSIONS: These findings add further understanding to the unique traits that characterize CNM individuals and the underlying motivational framework that may encourage individuals to initiate and maintain CNM relationships. Mitchell VE, Mogilski JK, Donaldson SH, et al. Sexual Motivation and Satisfaction Among Consensually Non-Monogamous and Monogamous Individuals. J Sex Med 2020;17:1072-1085.

Jealousy, Consent, and Compersion Within Monogamous and Consensually Non-Monogamous Romantic Relationships.

Evolutionary psychological research has studied romantic jealousy extensively within monogamous relationships, but has largely ignored jealousy among partners who mutually consent to forming extra-pair relationships (i.e., consensual non-monogamy; CNM). We examined monogamous (n = 529) and CNM (n = 159) individuals' reactions to imagining their romantic partner(s)'s extra-pair involvement. For each romantic partner, men and women completed measures of relationship jealousy and reacted to scenarios of their partner's extra-pair emotional and sexual involvement. Scenarios prompted participants to indicate which type of involvement would be more distressing and more enjoyable. They also described whether or not participants had consented to their partner's extradyadic relationship. Monogamous men were more distressed by a partner's extradyadic sexual versus emotional involvement (and a partner's emotional involvement was more enjoyable) whether the scenario was consensual or not. Monogamous women were more distressed by a partner's emotional versus sexual involvement (and a partner's sexual involvement was more enjoyable) for consensual, but not non-consensual, scenarios. There were no gender differences among CNM participants. Monogamous individuals reported greater emotional distress toward a partner's imagined extradyadic involvement, whereas CNM individuals reported thinking about their partner's extra-pair relationships more frequently. Monogamous (vs. CNM) individuals reported greater confidence that their partner would never cheat on them (i.e., enter another relationship without their consent), and CNM participants were more confident that their primary versus secondary partner would never cheat, although this effect was stronger among CNM women. Moreover, CNM participants rated that it was more important that their primary versus secondary partner did not cheat, and reported greater distress imagining that their primary versus secondary partner had cheated. Women in CNM relationships rated it more important that their partner did not cheat sexually than emotionally. Finally, we replicated previous research showing that monogamous individuals mate guard more than CNM individuals, who mate guard their primary versus secondary partner more frequently. Future directions for developing evolutionary and romantic relationship research on CNM are discussed.

Life History and Multi-Partner Mating: A Novel Explanation for Moral Stigma Against Consensual Non-monogamy.

Life history theory (LHT) predicts that individuals vary in their sexual, reproductive, parental, familial, and social behavior according to the physical and social challenges imposed upon them throughout development. LHT provides a framework for understanding why non-monogamy may be the target of significant moral condemnation: individuals who habitually form multiple romantic or sexual partnerships may pursue riskier, more competitive interpersonal strategies that strain social cooperation. We compared several indices of life history (i.e., the Mini-K, the High-K Strategy Scale, pubertal timing, sociosexuality, disease avoidance, and risk-taking) between individuals practicing monogamous and consensually non-monogamous (CNM) romantic relationships. Across several measures, CNM individuals reported a faster life history strategy than monogamous individuals, and women in CNM relationships reported earlier pubertal development. CNM individuals also reported more social and ethical risk-taking, less aversion to germs, and greater interest in short-term mating (and less interest in long-term mating) than monogamous individuals. From these data, we discuss a model to explain how moral stigma toward non-monogamy evolved and how these attitudes may be mismatched to the modern environment. Specifically, we argue that the culture of sexual ethics that pervades contemporary CNM communities (e.g., polyamory, swinging) may attenuate risky interpersonal behaviors (e.g., violent intrasexual competition, retributive jealousy, partner/child abandonment, disease transmission) that are relatively more common among those who pursue multi-partner mating.

The Relative Contribution of Jawbone and Cheekbone Prominence, Eyebrow Thickness, Eye Size, and Face Length to Evaluations of Facial Masculinity and Attractiveness: A Conjoint Data-Driven Approach.

Recent work demonstrates the methodological rigor of a type of data-driven analysis (i.e., conjoint analysis; CA), which accounts for the relative contribution of different facial morphological cues to interpersonal perceptions of romantic partner quality. This study extends this literature by using a conjoint face ranking task to predict the relative contribution of five sexually dimorphic facial shape features (jawbone and cheekbone prominence, eyebrow thickness, eye size, face length) to participants' (N = 922) perceptions of facial attractiveness and sex-typicality (i.e., masculinity/femininity). For overall partner attractiveness, eyebrow thickness and jawbone prominence were relatively more salient than cheekbone prominence and eye size. Interestingly, masculinized (i.e., thicker) eyebrows were marginally more attractive for female than male faces, particularly within a long-term mating context. Masculinized jawbone prominence was more attractive for male than female faces, and feminized jawbone prominence was more attractive for female than male faces. For perceptions of masculinity, eyebrow thickness, jawbone prominence, and facial height were relatively more salient than cheekbone prominence and eye size, although facial height was more important for female than male faces, and jawbone prominence was marginally more important for male than female faces. These findings highlight the prominence of eyebrows, the jawline, and facial height during perception of facial attractiveness and masculinity - though it should be noted that many of these differences were small to moderate in effect size. Findings are interpreted in the context of prior research, and future directions for studying why these facial traits exhibit superior signaling capacity are discussed.

Do Men Produce Higher Quality Ejaculates When Primed With Thoughts of Partner Infidelity?

Sperm competition theory can be used to generate the hypothesis that men alter the quality of their ejaculates as a function of sperm competition risk. Using a repeated measures experimental design, we investigated whether men produce a higher quality ejaculate when primed with cues to sperm competition (i.e., imagined partner infidelity) relative to a control prime. Men ( n = 45) submitted two masturbatory ejaculates-one ejaculate sample for each condition (i.e., sperm competition and control conditions). Ejaculates were assessed on 17 clinical parameters. The results did not support the hypothesis: Men did not produce higher quality ejaculates in the sperm competition condition relative to the control condition. Despite the null results of the current research, there is evidence for psychological and physiological adaptations to sperm competition in humans. We discuss methodological limitations that may have produced the null results and present methodological suggestions for research on human sperm competition.

Are there vocal cues to human developmental stability? Relationships between facial fluctuating asymmetry and voice attractiveness.

Fluctuating asymmetry (FA), deviation from perfect bilateral symmetry, is thought to reflect an organism's relative inability to maintain stable morphological development in the face of environmental and genetic stressors. Previous research has documented negative relationships between FA and attractiveness judgments in humans, but scant research has explored relationships between the human voice and this putative marker of genetic quality in either sex. Only one study (and in women only) has explored relationships between vocal attractiveness and asymmetry of the face, a feature-rich trait space central in prior work on human genetic quality and mate choice. We therefore examined this relationship in three studies comprising 231 men and 240 women from two Western samples as well as Hadza hunter-gatherers of Tanzania. Voice recordings were collected and rated for attractiveness, and FA was computed from two-dimensional facial images as well as, for a subset of men, three-dimensional facial scans. Through meta-analysis of our results and those of prior studies, we found a negative association between FA and vocal attractiveness that was highly robust and statistically significant whether we included effect sizes from previously published work, or only those from the present research, and regardless of the inclusion of any individual sample or method of assessing FA (e.g., facial or limb FA). Weighted mean correlations between FA and vocal attractiveness across studies were -.23 for men and -.29 for women. This research thus offers strong support for the hypothesis that voices provide cues to genetic quality in humans.

The Relative Importance of Sexual Dimorphism, Fluctuating Asymmetry, and Color Cues to Health during Evaluation of Potential Partners' Facial Photographs : A Conjoint Analysis Study.

Sexual dimorphism, symmetry, and coloration in human faces putatively signal information relevant to mate selection and reproduction. Although the independent contributions of these characteristics to judgments of attractiveness are well established, relatively few studies have examined whether individuals prioritize certain features over others. Here, participants (N = 542, 315 female) ranked six sets of facial photographs (3 male, 3 female) by their preference for starting long- and short-term romantic relationships with each person depicted. Composite-based digital transformations were applied such that each image set contained 11 different versions of the same identity. Each photograph in each image set had a unique combination of three traits: sexual dimorphism, symmetry, and color cues to health. Using conjoint analysis to evaluate participants' ranking decisions, we found that participants prioritized cues to sexual dimorphism over symmetry and color cues to health. Sexual dimorphism was also found to be relatively more important for the evaluation of male faces than for female faces, whereas symmetry and color cues to health were relatively more important for the evaluation of female faces than for male faces. Symmetry and color cues to health were more important for long-term versus short-term evaluations for female faces, but not male faces. Analyses of utility estimates reveal that our data are consistent with research showing that preferences for facial masculinity and femininity in male and female faces vary according to relationship context. These findings are interpreted in the context of previous work examining the influence of these facial attributes on romantic partner perception.

Monogamy versus Consensual Non-Monogamy: Alternative Approaches to Pursuing a Strategically Pluralistic Mating Strategy.

This study examined the frequency of partner-directed mate retention behaviors and several self- and partner-rated romantic relationship evaluations (i.e., sociosexuality, relationship satisfaction, mate value, and partner ideal measures) within monogamous and consensually non-monogamous (CNM) relationships. Measures were compared (1) between monogamous and CNM participants and (2) between two concurrent partners within each CNM relationship (i.e., primary and secondary partners). We found that individuals in currently monogamous relationships (n = 123) performed more mate retention behaviors compared to those currently in CNM relationships (n = 76). Within CNM relationships, participants reported engaging in more mate retention behaviors with primary partners compared to secondary partners. Likewise, CNM participants reported talking about their extra-dyadic sexual experiences and downplaying these sexual experiences more often with their primary partner compared to their secondary partner. There were no significant differences between ratings of monogamous and primary partners in participants' overall relationship satisfaction. However, monogamous participants reported less satisfaction with the amount of communication and openness they had with their partner compared to CNM participants' reports of their primary partner, but not secondary partner. By comparison, CNM participants reported higher overall relationship satisfaction with primary compared to secondary partners and considered their primary partner to be more desirable as a long-term mate than their secondary partner. We interpret these results within the context of previous research on monogamous and CNM relationships and hypothesize that these relationship configurations are alternative strategies for pursuing a strategically pluralistic mating strategy.

Effects of exogenous testosterone and mating context on men's preferences for female facial femininity.

Correlational research suggests that men show greater attraction to feminine female faces when their testosterone (T) levels are high. Men's preferences for feminine faces also seem to vary as a function of relationship context (short versus long-term). However, the relationship between T and preferences for female facial femininity has yet to be tested experimentally. In the current paper, we report the results of two experiments examining the causal role of T in modulating preferences for facial femininity across both short and long-term mating contexts. Results of Experiment 1 (within-subject design, n=24) showed that participants significantly preferred feminized versus masculinized versions of women's faces. Further, participants showed a stronger preference for feminine faces in the short versus the long-term context after they received T, but not after they received placebo. Post-hoc analyses suggested that this effect was driven by a lower preference for feminine faces in the long-term context when on T relative to placebo, and this effect was found exclusively for men who received placebo on the first day of testing, and T on the second day of testing (i.e., Order x Drug x Mating context interaction). In Experiment 2 (between-subject design, n=93), men demonstrated a significant preference for feminized female faces in the short versus the long-term context after T, but not after placebo administration. Collectively, these findings provide the first causal evidence that T modulates men's preferences for facial femininity as a function of mating context.

Sexual selection on male vocal fundamental frequency in humans and other anthropoids.

In many primates, including humans, the vocalizations of males and females differ dramatically, with male vocalizations and vocal anatomy often seeming to exaggerate apparent body size. These traits may be favoured by sexual selection because low-frequency male vocalizations intimidate rivals and/or attract females, but this hypothesis has not been systematically tested across primates, nor is it clear why competitors and potential mates should attend to vocalization frequencies. Here we show across anthropoids that sexual dimorphism in fundamental frequency (F0) increased during evolutionary transitions towards polygyny, and decreased during transitions towards monogamy. Surprisingly, humans exhibit greater F0 sexual dimorphism than any other ape. We also show that low-F0 vocalizations predict perceptions of men's dominance and attractiveness, and predict hormone profiles (low cortisol and high testosterone) related to immune function. These results suggest that low male F0 signals condition to competitors and mates, and evolved in male anthropoids in response to the intensity of mating competition.

Exogenous testosterone increases men's perceptions of their own physical dominance.

Men's testosterone is associated with several constructs that are linked to dominance rank, such as risk-taking, mating success, and aggression. However, no study has directly tested the relationship between men's self-perceived dominance and testosterone using an experimental design. We employed a within-subjects, double-blind, placebo-controlled paradigm to assess whether testosterone influences men's self-perceived dominance. Exogenous testosterone or a placebo was administered to healthy adult men and self-perceptions of physical dominance were subsequently assessed by having participants select what they believed to be their true face from an array of images digitally manipulated in masculinity. Men picked a more masculine version of their own face after testosterone versus placebo--an effect that was particularly pronounced among men with relatively low baseline testosterone. These findings indicate that a single administration of testosterone can rapidly modulate men's perceptions of their own physical dominance, which may explain links between testosterone and dominance-related behaviors.

Cognitive bias in rats is not influenced by oxytocin.

The effect of oxytocin on cognitive bias was investigated in rats in a modified conditioned place preference paradigm. Fifteen male rats were trained to discriminate between two different cue combinations, one paired with palatable foods (reward training), and the other paired with unpalatable food (aversive training). Next, their reactions to two ambiguous cue combinations were evaluated and their latency to contact the goal pot recorded. Rats were injected with either oxytocin (OT) or saline with the prediction that rats administered OT would display a shorter average latency to approach on ambiguous trials. There was no significant difference between latencies to approach on ambiguous trials compared to reward trials, but the rats were significantly slower on the aversive compared to the ambiguous conditions. Oxytocin did not affect approach time; however, it was unclear, after follow-up testing, whether the OT doses tested were sufficient to produce the desired effects on cognitive bias. Future research should consider this possibility.

The face of female dominance: Women with dominant faces have lower cortisol.

The human face displays a wealth of information, including information about dominance and fecundity. Dominance and fecundity are also associated with lower concentrations of the stress hormone cortisol, suggesting that cortisol may negatively predict facial dominance and attractiveness. We digitally photographed 61 women's faces, had these images rated by men and women for dominance, attractiveness, and femininity, and explored relationships between these perceptions and women's salivary cortisol concentrations. In a first study, we found that women with more dominant-appearing, but not more attractive, faces had lower cortisol levels. These associations were not due to age, ethnicity, time since waking, testosterone, or its interaction with cortisol. In a second study, composite images of women with low cortisol were perceived as more dominant than those of women with high cortisol significantly more often than chance by two samples of viewers, with a similar but non-significant trend in a third sample. However, data on perceptions of attractiveness were mixed; low-cortisol images were viewed as more attractive by two samples of US viewers and as less attractive by a sample of Mexican viewers. Our results suggest that having a more dominant-appearing face may be associated with lower stress and hence lower cortisol in women, and provide further evidence regarding the information content of the human face.