SEMPro: A Data-Driven Pipeline To Learn Structure-Property Insights from Scanning Electron Microscopy Images.

Analyzing hydrogel microstructure through scanning electron microscopy (SEM) images is crucial in understanding hydrogel properties. However, the analysis of SEM images in hydrogel research heavily relies on the intuition of individual researchers and is constrained by the limited size of the dataset. To address this, we propose SEMPro, a data-driven solution using web-scraping and deep learning (DL) to compile and analyze the structure-property relationships of hydrogels through SEM images. It accurately predicts the elastic modulus from SEM images within the same order of magnitude and displays a learned extraction of modulus-relevant features in SEM images as seen through the nontrivial activation mapping and transfer learning. By employing Explainable AI through activation map exposure, SEMPro validates the model predictions. SEMPro represents a closed-loop data collection and analysis pipeline, providing critical insights into hydrogels and soft materials. This innovative approach has the potential to revolutionize hydrogel research, offering high-dimensional insights for further advancements.

Stress Intensity and Exhaustion Among Infant and Toddler Teachers: Descriptive Analysis and Associations with Sources of Stress and Coping Strategy Use.

This study described infant/toddler teachers' (N = 106) perceptions of stress intensity and exhaustion (emotional, physical, mental) intensity. We examined the associations between stress and exhaustion and teachers' reports of stress sources and coping strategy use. Using ecological momentary assessment (EMA), teachers from Early Head Start (EHS), EHS childcare-partnerships, or independent childcare programs (midwestern U.S.) completed twice-weekly reports of: stress and exhaustion intensity; stress sources (workload, children's behaviors, personal life); and, coping strategies (support from colleagues, distraction, mindfulness techniques, reframing). Research Findings: Stress and exhaustion reports were similar to studies of preschool teachers. Workload and personal life stressors were associated with stress and all exhaustion types. Teachers used fewer than two different coping strategies/per reporting day. Only reframing was negatively associated with stress and emotional exhaustion. Teachers reported greater stress at end-of-week than beginning-of-week. Older teachers reported greater stress and emotional exhaustion. Although one-third of teachers reported ≥4 ACEs, early adversity was not associated with stress or exhaustion. Practice or Policy: We discuss the results relative to the sparse literature on infant/toddler teachers' well-being and suggest areas for professional development supports while underscoring the need for EHS federal policy makers and program administrators to consider how to reduce/streamline workload.

Microbial genome (Illumina MiSeq) sequencing of drinking water treatment residuals to evaluate compatibility with environmental applications.

The clarification of drinking water leads to the production of large quantities of water treatment residuals (WTRs). DNA was extracted from six WTR samples collected from water treatment plants within the UK to compare their bacterial communities and examine whether factors such as coagulant usage (aluminium versus iron salt), the type of water source (reservoir or river), or leachable chemical composition influence these communities. Bacterial 16S variable region 4 (V4) was amplified and sequenced using Illumina MiSeq sequencing. The most abundant phyla in WTR samples were Proteobacteria, Actinobacteria, Bacteroidetes, Acidobacteria, and Firmicutes, collectively representing 92.77-97.8% of the total bacterial sequences. Statistical analysis of microbial profiles indicated that water source played a significant role in microbial community structure, diversity, and richness, however coagulant type did not. PERMANOVA analysis showed that no single chemical variable (pH, organic matter, or extractable element concentration) influenced microbial composition significantly; however, canonical correspondence analysis of WTR microbiomes yielded a model using all these variables that could be used to explain variations in microbial community structures of WTRs (p < 0.05). No common, potentially toxic cyanobacteria, or related pathogens of concern were found. Analysis with PICRUSt showed that WTRs all had similar predicted microbial functional profiles. Overall, the results indicate that WTRs analysed in this study are unlikely to pose any threat to soil microbial community structure when applied to land as a soil conditioner or enhancer and may help to enhance the soil microbial community.

The High School to Higher Education Pipeline Program: A focus on Black male representation in nursing.

BACKGROUND: Increasing the number of Black men in nursing can enhance racial, ethnic, and gender diversity within the nursing workforce. However, there is a lack of nursing pipeline programs that specifically focus on Black men. PURPOSE: The purposes of this article are to describe the High School to Higher Education (H2H) Pipeline Program as an approach to increasing representation of Black men in nursing and to describe H2H Program participants' perspectives of the program after the first year. METHODS: A descriptive qualitative approach was used to explore Black males' perceptions of the H2H Program. Twelve of the 17 program participants completed questionnaires. Data collected were analyzed to identify themes. FINDINGS: Four themes emerged during data analysis regarding the participants' perspectives of the H2H Program: 1) Coming to realize, 2) Managing stereotypes, stigma, and social norms, 3) Making connections, and 4) Expressing gratitude. CONCLUSION: Results indicated that the H2H Program provided participants with a support network that fostered a sense of belonging. The H2H Program was beneficial for program participants in their development and engagement in nursing.

Anxiety and Associated Stressors Among Farm Women in England and Wales.

OBJECTIVES: The findings presented here derive from a wider study that sought to establish a baseline understanding of mental health and wellbeing among the agricultural community in England and Wales. This paper focuses on selected questions that investigated levels of anxiety and associated stress factors among farm women, a group which has been relatively neglected within previous research on farming mental health in the United Kingdom. METHODS: A questionnaire survey was widely distributed to members of the agricultural community in England and Wales (n = 15,296) in both paper and online formats. The survey included a number of standardised instruments to assess mental health and wellbeing, including the Generalised Anxiety Disorder-7 scale (GAD-7). Focusing on a sub-sample of female respondents (n = 3487), this paper details the findings from the GAD-7, alongside those from a selection of other questions investigating sources of stress, loneliness and perceived business viability. RESULTS: A significant proportion of female respondents were experiencing anxiety at the time of survey completion, with 23.3% reaching the threshold for clinically relevant anxiety based on their GAD-7 scores (medium or severe anxiety, scores≥10). A further 34.6% were classified as experiencing mild anxiety (scores 5-9) whilst 42.1% were not suffering from anxiety (scores 0-4). Medium/severe anxiety was identified as being associated with a number of stress factors, feelings of loneliness and pessimistic perceptions of farm business viability. There were important age-based differences, with working-aged women identified as more likely to suffer from anxiety, loneliness and certain stressors than older women. CONCLUSION: The findings reported here indicate concerning levels of anxiety among farming women and this should be seen as a call to action. There are clear associations between anxiety and a range of stressors and, although we cannot ascertain causality, these point to issues that demand attention in efforts to improve mental health within this social group. The factors contributing to anxiety are, however, multiple and complex and farm women may be affected by particular gender-based challenges that have not yet been explicitly explored in relation to mental health. Further research is needed to investigate and understand these issues in greater depth.

Health-related quality of life within agriculture in England and Wales: results from a EQ-5D-3L self-report questionnaire.

BACKGROUND: Mental and physical health problems among the farming community are well documented but there is limited evidence regarding the overall health status of this population. This paper offers a unique insight into this issue through presenting the findings from a survey instrument, the EQ-5D-3L, which provides a standardised measure of health-related quality of life (HRQOL). METHODS: We conducted the largest ever survey (n = 15,296) of people living and working in agriculture in England and Wales to gather baseline data on health and wellbeing within this community. The survey included an assessment of HRQOL through the use of the EQ-5D-3L self-report questionnaire. A variety of statistical approaches were used to test for significant associations between HRQOL and sub-group characteristics, including the Chi-square test for independence, the Kruskal-Wallis test, and Mann-Whitney U-test. Binary logistic regression models were also created to assess the influence of a set of respondent characteristics on the likelihood of respondents reporting health problems in the EQ-5D-3L. RESULTS: 24% of respondents reported problems with mobility; 4% reported problems with self-care; 21% reported problems with performing their usual activities; 52% reported problems with pain/discomfort; and 31% reported problems with anxiety/depression. The mean EQ-5D index value was 0.811 (median (Md) 0.796, interquartile range (IQR) 0.275). The mean self-rated health score (EQ-VAS) was 77.6 (SD 16.1) (Md 80.0, IQR 20). In general, holding other respondent characteristics equal, women reported fewer problems with mobility, self-care, performing usual activities and pain/discomfort than men, but more problems with anxiety/depression. HRQOL in the working-aged appears to be poorer among the survey population than the wider UK population. CONCLUSIONS: Results reveal concerning levels of physical and mental health problems, especially pain/discomfort and anxiety/depression, which appear to be more prevalent within our sample than within the wider UK population. There were important gender and age-related differences in both mental and physical health. Combatting these problems through targeted support is essential for the wellbeing of the farming community and the future sustainability of UK food production.

Evaluating land application of pulp and paper mill sludge: A review.

It is estimated that >400 Mt of board and paper are produced globally per year, and that 4.3-40 kg (dw) of sludge like material, pulp and paper mill sludge (PPMS), is generated for every tonne of product. PPMS are now more widely reused in agriculture as a soil amendment due to their high organic content of 40-50% by weight, perceived low toxicity and possible liming capabilities. Within this review article historic and recent literature on PPMS land spreading are combined with knowledge of European and UK regulation to explore the benefits, potential impacts and viability of land spreading PPMS. The review reveals that risks relating to potential N immobilisation in soils post-application can be readily mitigated, if desired, by coapplication of an N source, or even pre-treatment of sludge via composting. The benefits to crops have been demonstrated emphatically, while negative ecological impacts under typical field application rates have not been observed to date. The case is therefore strong for continued land application of the material as an environmentally responsible and sustainable use option. However, there are currently gaps in the literature regarding longer-term implications of PPMS applications in agriculture and in regards to the possible presence of emerging contaminants in some PPMS materials, both of which have been identified as areas that merit further research.

State and national data on the Georgia nursing workforce.

BACKGROUND: The enduring absence of robust nursing workforce data creates gaps to support evidence-based workforce planning and policy development. PURPOSE: The purpose of this study was to examine Georgia nursing workforce data available through state and national agencies to determine if significance differences exist among data sources. METHODS: A cross-sectional, descriptive analysis of 2017 Georgia nursing workforce data was used to examine and compare workforce characteristics available from five data sources. The advantages and limitations of each data source were reviewed. FINDINGS: Significant differences were noted in the quality and quantity of data collected on the Georgia nursing workforce as reported by state and national agencies. None of the datasets include in our analysis had comprehensive and timely data on the Georgia nursing workforce. DISCUSSION: Nursing workforce stakeholders must work collaboratively to require and implement a comprehensive re-licensure survey. It is only though a standardized national minimum dataset that we can ensure an adequate nursing workforce.

Assessing the Impacts of Land Spreading Water-Treatment Residuals on the Anecic Earthworm Lumbricus terrestris, Soil Microbial Activity, and Porewater Chemistry.

Water-treatment residuals (WTRs), by-products of drinking water clarification, are increasingly recycled to land to promote circular economy and reduce disposal costs, yet there is a lack of published literature on their effects on soil ecology. In the present study, the effects of WTRs on earthworm growth, soil respiration, and soil porewater chemistry were investigated throughout a 7-wk outdoor mesocosm trial. We derived WTRs from both aluminum and iron coagulants and applied them to a loam soil at 0 to 20% (w/w). In addition, soil from a field that had received long-term WTR applications and that of an adjacent nontreated reference field were included in the study. Earthworm mass increase was significantly higher in all but one laboratory-treated soil when compared to the control. Furthermore, a linear regression model was used to predict increases in weekly soil respiration based on the application rates of both Al and Fe WTRs. In addition, a significant increase in soil respiration was observed from the treated farm soils during the first 4 wk of the trial. Measured sodium, magnesium, potassium, and iron porewater concentrations were higher in the treated farm soils than the reference site soil in a majority of samples, although these differences may be related to land management. Laboratory-treated soils had elevated porewater arsenic concentrations (e.g., ~17 µg L-1 in controls vs ~62 µg L-1 in the 20% w/w Al WTR treatment in week 1), whereas porewater nickel concentrations were, respectively, elevated and lowered in Al WTR- and Fe WTR-amended samples. Overall, observed disturbances to soil ecology were determined to be minimal. Environ Toxicol Chem 2021;40:1964-1972. © 2021 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.

Using Self-Generated Cues to Facilitate Recall: A Narrative Review.

We draw upon the Associative Network model of memory, as well as the principles of encoding-retrieval specificity, and cue distinctiveness, to argue that self-generated cue mnemonics offer an intuitive means of facilitating reliable recall of personally experienced events. The use of a self-generated cue mnemonic allows for the spreading activation nature of memory, whilst also presenting an opportunity to capitalize upon cue distinctiveness. Here, we present the theoretical rationale behind the use of this technique, and highlight the distinction between a self-generated cue and a self-referent cue in autobiographical memory research. We contrast this mnemonic with a similar retrieval technique, Mental Reinstatement of Context, which is recognized as the most effective mnemonic component of the Cognitive Interview. Mental Reinstatement of Context is based upon the principle of encoding-retrieval specificity, whereby the overlap between encoded information and retrieval cue predicts the likelihood of accurate recall. However, it does not incorporate the potential additional benefit of self-generated retrieval cues.

Perspectives of Nurses Pursuing Doctoral Degrees in Georgia: Implications for Recruitment.

BACKGROUND: Increasing the number of nurses with doctorates is a goal of the nursing profession. The Georgia Nursing Leadership Coalition developed a survey to understand the perspectives of nurses pursuing doctoral degrees in Georgia to improve recruitment and retention strategies. METHOD: A 26-item online survey was distributed to all students enrolled in Georgia-based doctoral programs in nursing in spring 2014. RESULTS: One hundred fifty responses were received (54% response rate). Most students first seriously considered doctoral education during their master's programs or more than 5 years into practice. For most, obtaining a doctoral degree was a personal life goal. Work-life balance was the most significant barrier. CONCLUSION: Recruitment of nurses to doctoral programs should focus on messaging, timing, and highlighting the unique aspects of programs. Schools should work to reduce barriers. Understanding students' perspectives of doctoral education in nursing can improve recruitment strategies and increase the number of nurses graduating with doctorates in Georgia. [J Nurs Educ. 2017;56(8):466-470.].

Supporting Doctoral Students and Faculty: The Development of an Annual Doctoral Symposium.

AIM: The aim of the study was to develop a sustainable annual symposium to support doctoral students in nursing across the state of Georgia. BACKGROUND: A goal of the nursing profession, highlighted in the Institute of Medicine Future of Nursing report of 2011, is to increase the number of nurses with doctorates. They are needed to fill faculty positions as professors retire and to step into leadership positions as health care systems become more complex. METHOD: The Georgia Nursing Leadership Coalition developed a Doctoral Symposium in 2014 that has been repeated annually. RESULTS: The Doctoral Symposium gives doctoral students and faculty the opportunity to network, discuss current issues, advance their skills, and (for students) share their work. Approximately 100 people attend each year; costs and attendance fees have been kept low. Lessons learned are provided. CONCLUSION: The Doctoral Symposium is a sustainable, valuable activity for supporting doctoral students and faculty.

Maternal Depressive Symptoms and At-Risk Young Children's Internalizing Problems: The Moderating Role of Mothers' Positivity.

Maternal depressive symptoms predict negative child behaviors, including internalizing problems. However, protective factors, such as positive emotionality and positive parenting behaviors, may play an important a role in attenuating associations between maternal depressive symptoms and child behavior problems. This manuscript presents two studies that examined buffers of links between maternal depressive symptoms and child internalizing problems. Each study examined samples of primarily African American families with young children in an impoverished large city in the Midwestern United States. Families were recruited from kindergarten classes and Women, Infants, and Children (WIC) centers. In both studies, indicators of mothers' positivity, as measured by text based analysis of positive emotion word use or behavioral observation of positive parenting behaviors, attenuated links between maternal depressive symptoms and child internalizing problems. The results suggest that risk for internalizing problems within the context of maternal depressive symptoms is reduced when parents experience and express more positive emotions and behaviors.

On the persuadability of memory: Is changing people's memories no more than changing their minds?

The observation of parallels between the memory distortion and persuasion literatures leads, quite logically, to the appealing notion that people can be 'persuaded' to change their memories. Indeed, numerous studies show that memory can be influenced and distorted by a variety of persuasive tactics, and the theoretical accounts commonly used by researchers to explain episodic and autobiographical memory distortion phenomena can generally predict and explain these persuasion effects. Yet, despite these empirical and theoretical overlaps, explicit reference to persuasion and attitude-change research in the memory distortion literature is surprisingly rare. In this paper, we argue that stronger theoretical foundations are needed to draw the memory distortion and persuasion literatures together in a productive direction. We reason that theoretical approaches to remembering that distinguish (false) beliefs in the occurrence of events from (false) memories of those events - compatible with a source monitoring approach - would be beneficial to this end. Such approaches, we argue, would provide a stronger platform to use persuasion findings to enhance the psychological understanding of memory distortion.

The reduced cost of providing a nationally recognised service for familial hypercholesterolaemia.

OBJECTIVE: Familial hypercholesterolaemia (FH) affects 1 in 500 people in the UK population and is associated with premature morbidity and mortality from coronary heart disease. In 2008, National Institute for Health and Care Excellence (NICE) recommended genetic testing of potential FH index cases and cascade testing of their relatives. Commissioners have been slow to respond although there is strong evidence of cost and clinical effectiveness. Our study quantifies the recent reduced cost of providing a FH service using generic atorvastatin and compares NICE costing estimates with three suggested alternative models of care (a specialist-led service, a dual model service where general practitioners (GPs) can access specialist advice, and a GP-led service). METHODS: Revision of existing 3 year costing template provided by NICE for FH services, and prediction of costs for running a programme over 10 years. Costs were modelled for the first population-based FH service in England which covers Southampton, Hampshire, Isle of Wight and Portsmouth (SHIP). Population 1.95 million. RESULTS: With expiry of the Lipitor (Pfizer atorvastatin) patent the cost of providing a 10-year FH service in SHIP reduces by 42.5% (£4.88 million on patent vs £2.80 million off patent). Further cost reductions are possible as a result of the reduced cost of DNA testing, more management in general practice, and lower referral rates to specialists. For instance a dual-care model with GP management of patients supported by specialist advice when required, costs £1.89 million. CONCLUSIONS: The three alternative models of care are now <50% of the cost of the original estimates undertaken by NICE.

The experience of discrimination by US and Internationally educated nurses in hospital practice in the USA: a qualitative study.

AIM: To document experiences of nurses educated abroad and in the USA in 2 urban hospitals in the southeastern USA. BACKGROUND: Nurses are responsible for providing quality patient care. Discrimination against nurses in the workplace may create hostile environments, potentially affecting patient care and leading to higher nurse attrition rates. Structuration theory posits that agents' interactions create structures. Agents' use of resources and rules shapes interactions, potentially changing the structures. In this study, nurses described interactions with patients and their families and other healthcare personnel, their strategies for managing interactions and rationales behind their selected strategy. DESIGN: This study employed a qualitative, explorative approach using structuration theory. METHODS: In 2011, 42 internationally educated and 40 USA-educated nurses practising in two urban hospitals in the southeastern USA were interviewed about their experiences in the workplace. Forty-one nurses were re-interviewed to explore the issues raised in the preliminary round: 21 internationally educated and 20 USA. Transcripts were analysed using the constant comparative method. FINDINGS: Although internationally educated nurses experienced more explicit discrimination, all nurses experienced discrimination from their patients, their nurse colleagues and/or other hospital personnel. Internationally educated nurses and USA nurses shared similar coping strategies. CONCLUSION: The prevalence of nurses' experiences of discrimination suggests that healthcare institutions need to strengthen policies to effectively address this harmful practice. More research is needed about discrimination against nurses in the workplace because discrimination may have serious psychological effects that impact nurse retention and the quality of patient care.

Alcohol increases hypnotic susceptibility.

One approach to hypnosis suggests that for hypnotic experience to occur frontal lobe activity must be attenuated. For example, cold control theory posits that a lack of awareness of intentions is responsible for the experience of involuntariness and/or the subjective reality of hypnotic suggestions. The mid-dorso-lateral prefrontal cortex and the ACC are candidate regions for such awareness. Alcohol impairs frontal lobe executive function. This study examined whether alcohol affects hypnotisability. We administered 0.8 mg/kg of alcohol or a placebo to 32 medium susceptible participants. They were subsequently hypnotised and given hypnotic suggestions. All participants believed they had received some alcohol. Participants in the alcohol condition were more susceptible to hypnotic suggestions than participants in the placebo condition. Impaired frontal lobe activity facilitates hypnotic responding, which supports theories postulating that attenuation of executive function facilitates hypnotic response, and contradicts theories postulating that hypnotic response involves enhanced inhibitory, attentional or other executive function.

Barriers to participation in governance and professional advancement: a comparison of internationally educated nurses and registered nurses educated in the United States.

OBJECTIVE: This study compared the perspectives of internationally educated nurses (IENs) and registered nurses (RNs) educated in the United States regarding participation in hospital governance structures and professional advancement. BACKGROUND: Nurses' participation in hospital governance is reported to contribute to empowerment. No research has examined how IENs' perceptions about participation in governance compared with those of U.S. RNs. METHODS: Semistructured interviews were held with 82 nurses in 2 urban hospitals. Forty nurses were reinterviewed to follow up on themes. RESULTS: Internationally educated nurses and US RNs shared similar perspectives. Nurses in both samples did not value participation in governance, lacked guidance about how to advance, and preferred to at the bedside. CONCLUSIONS: Strategies to encourage nurses to participate in and value governance and professional advancement opportunities should be explored and adopted.

Explicit mentalizing mechanisms and their adaptive role in memory conformity.

Memory conformity occurs when an individual endorses what other individuals remember about past events. Research on memory conformity is currently dominated by a 'forensic' perspective, which views the phenomenon as inherently undesirable. This is because conformity not only distorts the accuracy of an individual's memory, but also produces false corroboration between individuals, effects that act to undermine criminal justice systems. There is growing awareness, however, that memory conformity may be interpreted more generally as an adaptive social behavior regulated by explicit mentalizing mechanisms. Here, we provide novel evidence in support of this emerging alternative theoretical perspective. We carried out a memory conformity experiment which revealed that explicit belief-simulation (i.e. using one's own beliefs to model what other people believe) systematically biases conformity towards like-minded individuals, even when there is no objective evidence that they have a more accurate memory than dissimilar individuals. We suggest that this bias is functional, i.e. adaptive, to the extent that it fosters trust, and hence cooperation, between in-group versus out-group individuals. We conclude that memory conformity is, in more fundamental terms, a highly desirable product of explicit mentalizing mechanisms that promote adaptive forms of social learning and cooperation.