1.
The CCR5Delta32 allele is associated with reduced liver inflammation in hepatitis C virus infection.
Eur J Immunogenet
; 31(6): 249-52, 2004 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-15548261
RESUMO
CCR5Delta32 is a deletion mutation in the chemokine receptor CCR5. Liver inflammatory activity was found to be significantly reduced (P = 0.005) in Jewish Israeli patients infected with the hepatitis C virus (HCV) carrying the CCR5Delta32 allele. The CCR5Delta32 allele does not alter susceptibility to HCV infection; however, it may play a role in the progression and outcome of the disease.