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Ugeskr Laeger ; 173(46): 2957-9, 2011 Nov 14.
Artigo em Dinamarquês | MEDLINE | ID: mdl-22094217

RESUMO

Case reports of three children with autoimmune neutropenia are presented. The children had a number of infections, which required antibiotic treatment, mostly respiratory tract infections, but one child had a septic coxitis. During a follow-up period of 1-3 years, only one patient showed complete remission after 15 months of neutropenia. One child was treated with granulocyte colony-stimulating factor without effect, whereas two children received prophylactic antibiotics with clinical benefit. In view of the frequent infections and benefit of prophylactic measures, children with neutropenia or an inappropriately low neutrophil count during bacterial infections should be evaluated for autoimmune neutropenia.


Assuntos
Doenças Autoimunes , Neutropenia , Antibioticoprofilaxia , Doenças Autoimunes/diagnóstico , Doenças Autoimunes/tratamento farmacológico , Infecções Bacterianas/diagnóstico , Infecções Bacterianas/tratamento farmacológico , Diagnóstico Diferencial , Feminino , Granulócitos/imunologia , Humanos , Lactente , Contagem de Leucócitos , Masculino , Neutropenia/diagnóstico , Neutropenia/tratamento farmacológico , Neutrófilos/imunologia
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