[Evaluation of early results and failures of radiotherapy in patients with cancer of the oral cavity and throat]. / Ocena wczesnych wyników i niepowodzen w leczeniu napromienianiem chorych na raka jamy ustnej i gardla.

Since 1986 to 1989 in the Department of Teleradiotherapy of Center Oncology--Institute branch Gliwice 102 patients with oral cavity cancers and 114 with pharyngeal cancers were treated. Patients underwent external radiation, which was delivered with Co60 to the dose 70 Gy on the tumor and additionally regional lymph nodes were irradiated with 10 MeV linear accelerator. There were 69 patients (32%) with stage T-2 and 147 patients (68%) in stage T-3. Metastatic regional lymph nodes in 130 patients (60%) were recognized. Free of disease one year survival in 98 patients (45%) was observed: 41% with oral cavity cancer and 49% with pharyngeal cancer. The conclusion suggests that the results depend on the size of the tumor and presence of the metastatic lymph nodes. Among the patients with oral cavity cancer in 40% with free nodes and 69% with metastatic nodes unsuccessful treatment was observed. In the group with pharyngeal cancer percentage were 35% and 63% respectively. Results of the treatment, were unsatisfactory when diameter of metastatic nodes was more than 5 cm (N-3).

[Cancer of the pharynx--results of treatment with cobalt-60]. / Rak gardla--wyniki leczenia kobaltem 60.

One hundred two patients with pharyngeal cancer had been treated from 1980 to 1984 in Center Oncology--Institute branch Gliwice. Total radiation doses were 60-65 Gy. From the group of 44 patients without metastatic lymph nodes, 5 year survival rate was 36%. In cases with advanced pharyngeal carcinoma and with metastases to the lymph nodes (58 patients), 5 year survival rate was 18%. The results of this study suggest that survival rates depend on the size of the tumor and presence metastases to the local lymph nodes.

[Cobalt teletherapy of patients with pharyngeal cancer]. / Telekobaltoterapia u chorych na raka gardla.

127 patients with pharyngeal cancer were irradiated in the years 1970-1979 with telecobalt-60 in total doses of 60-65 Gy. In the group with not advanced pharyngeal cancer 34% of patients survived during 5 years without any symptoms of neoplasm. In the group with advanced pharyngeal cancer and lymph nodes metastases the 5 years survival was within 15%. The 5-years survival depended mainly upon the extensiveness of the neoplasm. The therapeutic results were influenced also by the age of the patient; 35% were above 60 years of age and 17.3% died before the 5 years period without any symptoms of cancer.

The epidemiological risk factors of the larynx cancer among the native and migrant male population.

In the present paper relative risk of larynx cancer has been evaluated in 272 cases in the stationary (native Upper Silesians) (65.4%) and migrant (34.6%) population of men. The corresponding control groups (total 739 men) consisted of 401 (54.3%) and 338 (45.7%) men, respectively, who did not suffer from neoplastic diseases. The important relationship between larynx cancer incidence and cigarette (with or without filter), pipe and cigar smoking has been proved. It has also been shown that the evaluation of larynx cancer risk according to the birth place of populations is more useful, because it enables to discover new epidemiological aspects of the larynx cancer. The higher larynx cancer risk has also been disclosed in men who are in manual work, and who are immediately exposed to the influence of various dusts and gases in their place of work. It has been discovered, that chronic inflammation of the upper respiratory tract, pneumonia, tuberculosis, emphysema or bronchitis also influence higher larynx cancer incidence risk in the native and migrant populations analysed.