Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
2.
Med Phys ; 36(10): 4711-9, 2009 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-19928102

RESUMO

PURPOSE: Brachytherapy treatment has been a cornerstone for management of various cancer sites, particularly for the treatment of gynecological malignancies. In low dose rate brachytherapy treatments, 137Cs sources have been used for several decades. A new 137Cs source design has been introduced (model 67-6520, source B3-561) by Isotope Products Laboratories (IPL) for clinical application. The goal of the present work is to implement the TG-43 U1 protocol in the characterization of the aforementioned 137Cs source. METHODS: The dosimetric characteristics of the IPL 137Cs source are measured using LiF thermoluminescent dosimeters in a Solid Water phantom material and calculated using Monte Carlo simulations with the GEANT4 code in Solid Water and liquid water. The dose rate constant, radial dose function, and two-dimensional anisotropy function of this source model were obtained following the TG-43 U1 recommendations. In addition, the primary and scatter dose separation (PSS) formalism that could be used in convolution/superposition methods to calculate dose distributions around brachytherapy sources in heterogeneous media was studied. RESULTS: The measured and calculated dose rate constants of the IPL 137Cs source in Solid Water were found to be 0.930 (+/-7.3%) and 0.928 (+/-2.6%) cGy h(-1) U(-1), respectively. The agreement between these two methods was within our experimental uncertainties. The Monte Carlo calculated value in liquid water of the dose rate constant was null set=0.948 (+/-2.6%) cGy h(-1) U(-1). Similarly, the agreement between measured and calculated radial dose functions and the anisotropy functions was found to be within +/-5%. In addition, the tabulated data that are required to characterize the source using the PSS formalism were derived. CONCLUSIONS: In this article the complete dosimetry of the newly designed 137Cs IPL source following the AAPM TG-43 U1 dosimetric protocol and the PSS formalism is provided.


Assuntos
Braquiterapia/instrumentação , Braquiterapia/normas , Radioisótopos de Césio/química , Radioisótopos de Césio/normas , Guias como Assunto , Próteses e Implantes/normas , Radioisótopos de Césio/uso terapêutico , Internacionalidade , Compostos Radiofarmacêuticos/análise , Compostos Radiofarmacêuticos/química , Compostos Radiofarmacêuticos/normas , Compostos Radiofarmacêuticos/uso terapêutico , Padrões de Referência
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...