RESUMO
We report a supramolecular approach for the preparation of photostable NIR nanovesicles based on a cyanine dye derivative as a photoacoustic (PA) contrast agent for high-performance nano-imaging.
Assuntos
Técnicas Fotoacústicas , Espectroscopia de Luz Próxima ao Infravermelho , Animais , Carbocianinas/química , Meios de Contraste/química , Estabilidade de Medicamentos , Xenoenxertos/diagnóstico por imagem , Humanos , Luz , Camundongos , Estrutura Molecular , Nanotecnologia , Neoplasias/diagnóstico por imagem , RadiografiaRESUMO
A novel Cd(II) metal-organic framework, [Cd(C(3)H(2)O(4))(NH(3))](n), was synthesized by liquid diffusion conducted in the presence of ammonia. The Cd(II) atom has seven-coordinate O(6)N pentagonal-bipyramidal geometry. Six Cd(II) centers are joined by six malonate ligands to form an S(6)-symmetric [Cd(6)(malonate)(6)] metallomacrocycle, which is further extended through a side-on chelating malonate ligand to form a three-dimensional network. Topologically, each Cd(II) center is connected to four others to yield an infinite three-periodic four-coordinated SOD (sodalite) network with point symbol {4(2)·6(4)}. The overall network structure in the crystal is maintained and stabilized by the presence of N-H...O hydrogen bonds.