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1.
Artigo em Inglês | MEDLINE | ID: mdl-37021999

RESUMO

In this paper, we propose the t-FDP model, a force-directed placement method based on a novel bounded short-range force (t-force) defined by Student's t-distribution. Our formulation is flexible, exerts limited repulsive forces for nearby nodes and can be adapted separately in its short- and long-range effects. Using such forces in force-directed graph layouts yields better neighborhood preservation than current methods, while maintaining low stress errors. Our efficient implementation using a Fast Fourier Transform is one order of magnitude faster than state-of-the-art methods and two orders faster on the GPU, enabling us to perform parameter tuning by globally and locally adjusting the t-force in real-time for complex graphs. We demonstrate the quality of our approach by numerical evaluation against state-of-the-art approaches and extensions for interactive exploration.

2.
IEEE Trans Vis Comput Graph ; 29(10): 4256-4268, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-35786556

RESUMO

We present Target Netgrams as a visualization technique for radial layouts of graphs. Inspired by manually created target sociograms, we propose an annulus-constrained stress model that aims to position nodes onto the annuli between adjacent circles for indicating their radial hierarchy, while maintaining the network structure (clusters and neighborhoods) and improving readability as much as possible. This is achieved by having more space on the annuli than traditional layout techniques. By adapting stress majorization to this model, the layout is computed as a constrained least square optimization problem. Additional constraints (e.g., parent-child preservation, attribute-based clusters and structure-aware radii) are provided for exploring nodes, edges, and levels of interest. We demonstrate the effectiveness of our method through a comprehensive evaluation, a user study, and a case study.

3.
IEEE Trans Vis Comput Graph ; 29(1): 886-895, 2023 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-36166546

RESUMO

Over the past few decades, a large number of graph layout techniques have been proposed for visualizing graphs from various domains. In this paper, we present a general framework, Taurus, for unifying popular techniques such as the spring-electrical model, stress model, and maxent-stress model. It is based on a unified force representation, which formulates most existing techniques as a combination of quotient-based forces that combine power functions of graph-theoretical and Euclidean distances. This representation enables us to compare the strengths and weaknesses of existing techniques, while facilitating the development of new methods. Based on this, we propose a new balanced stress model (BSM) that is able to layout graphs in superior quality. In addition, we introduce a universal augmented stochastic gradient descent (SGD) optimizer that efficiently finds proper solutions for all layout techniques. To demonstrate the power of our framework, we conduct a comprehensive evaluation of existing techniques on a large number of synthetic and real graphs. We release an open-source package, which facilitates easy comparison of different graph layout methods for any graph input as well as effectively creating customized graph layout techniques.

4.
Analyst ; 146(21): 6470-6473, 2021 Oct 25.
Artigo em Inglês | MEDLINE | ID: mdl-34609387

RESUMO

A novel and low-cost DNAzyme, Ni/Fe layered double hydroxide (LDH) nanosheet/G-quadruplex (without hemin) with enhanced peroxidase-mimic activity was designed. The catalytic mechanism was investigated. The detection of Cu(II) in actual serum samples could be realized sensitively via this efficient DNAzyme-based method.


Assuntos
Técnicas Biossensoriais , DNA Catalítico , Quadruplex G , DNA Catalítico/metabolismo , Hemina , Hidróxidos , Peroxidase , Peroxidases
5.
Analyst ; 146(22): 6726-6740, 2021 Nov 08.
Artigo em Inglês | MEDLINE | ID: mdl-34693409

RESUMO

In recent years, Au and Ag nanomaterials have been widely used in the determination of glucose owing to their specific properties such as large specific surface area, high extinction coefficient, strong localized surface plasmon resonance effect and enzyme-mimicking activity. Compared with other methods, colorimetric determination of glucose with Au or Ag nanomaterials features the advantages of simple operation, low cost and easy observation. In this review, several typical synthesis methods of Au and Ag nanomaterials are introduced. Strategies for the colorimetric determination of glucose by Au or Ag nanomaterials are elaborated. The challenges and prospects of the application of Au or Ag nanomaterials for colorimetric detection of glucose are also discussed.


Assuntos
Nanopartículas Metálicas , Nanoestruturas , Colorimetria , Glucose , Ouro , Prata
6.
IEEE Trans Vis Comput Graph ; 26(1): 687-696, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31443025

RESUMO

Many edge bundling techniques (i.e., data simplification as a support for data visualization and decision making) exist but they are not directly applicable to any kind of dataset and their parameters are often too abstract and difficult to set up. As a result, this hinders the user ability to create efficient aggregated visualizations. To address these issues, we investigated a novel way of handling visual aggregation with a task-driven and user-centered approach. Given a graph, our approach produces a decluttered view as follows: first, the user investigates different edge bundling results and specifies areas, where certain edge bundling techniques would provide user-desired results. Second, our system then computes a smooth and structural preserving transition between these specified areas. Lastly, the user can further fine-tune the global visualization with a direct manipulation technique to remove the local ambiguity and to apply different visual deformations. In this paper, we provide details for our design rationale and implementation. Also, we show how our algorithm gives more suitable results compared to current edge bundling techniques, and in the end, we provide concrete instances of usages, where the algorithm combines various edge bundling results to support diverse data exploration and visualizations.

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