The value of combined detection of sFIt-1, PLGF and Survivin in the diagnosis of early-onset preeclampsia / 中国医师进修杂志

s] Objective To analyze the diagnostic value of combined detection of sFIt-1, PLGF and Survivin in early onset preeclampsia. Methods From January 2017 to January 2018, 100 patients with early-onset PE were selected as observation group and 100 healthy pregnant women as control group in Tangshan Maternal and Child health Hospital Gynecology and Obstetrics. The expression levels of sFIt-1, PLGF and Survivin in serum were detected by enzyme-linked immunosorbent assay (ELISA), and the diagnostic value of each index was analyzed separately and jointly. Results The levels of sFIt-1 in the observation group were significantly higher than those in the control group: (36.58 ± 18.34) μg/L vs. (28.43 ± 3.28) μg/L (P<0.05), and the levels of PLGF and Survivin in the observation group were significantly lower than those in the control group: (213.18 ± 48.23) ng/L vs. (398.17 ± 41.19) ng/L, (0.72 ± 0.29) μg/L vs. (1.43 ± 0.32) μg/L (P<0.05); 103 cases of positive sFIt-1, 108 cases of positive PLGF, 107 cases of positive Survivin, 121 cases of positive parallel combined diagnosis and 121 cases of positive series combined diagnosis were found. The sensitivity and negative predictive value of parallel combined diagnosis were significantly higher than those of individualized diagnosis (P<0.05), and the specificity and positive predictive value of series combined diagnosis were significantly higher than those of individualized diagnosis (P < 0.05). Conclusions The combined detection of sFIt-1, PLGF and Survivin in serum can effectively improve the diagnostic accuracy of early-onset preeclampsia and has high clinical value.

Prevention and treatment of fat liquefaction in gynecological obese patients after abdominal incision / 中国基层医药

Objective To explore the best fat liquefaction prevention measures for gynecological obese patients with abdominal incision.Methods 84 gynecological obese patients with abdominal incision were divided into the observation group(46 cases)and control group(38 cases),according to the negative pressure attract ball placed or not in the subcutaneous fat layer during operation.Patients in both groups were taken abdominal incision physiotherapy.Results The fat liquefaction rate of the observation group was 8.7％,which was lower than that of the control group(26.3％)(x2=4.65,P＜0.05).Conclusion It is very important to keep the incision dry,smooth drainage for prevention and treatment of fat liquefaction in gynecological obese patients after abdominal incision.