Neural correlates of pronoun processing: An activation likelihood estimation meta-analysis.

Pronouns are unique linguistic devices that allow for the expression of referential relationships. Despite their communicative utility, the neural correlates of the operations involved in reference assignment and/or resolution, are not well-understood. The present study synthesized the neuroimaging literature on pronoun processing to test extant theories of pronoun comprehension. Following the PRISMA guidelines and thebest-practice recommendations for neuroimaging meta-analyses, a systematic literature search and record assessment were performed. As a result, 16 fMRI studies were included in the meta-analysis, and were coded in Scribe 3.6 for inclusion in the BrainMap database. The activation coordinates for the contrasts of interest were transformed into Talairach space and submitted to an Activation Likelihood Estimation (ALE) meta-analysis in GingerALE 3.0.1. The results indicated that pronoun processing had functional convergence in the left posterior middle and superior temporal gyri, potentially reflecting the retrieval, prediction and integration roles of these areas for pronoun processing.

The Moroccan Arabic Bedside Western Aphasia Battery-Revised: Linguistic and Psychometric Properties.

PURPOSE: The objectives of this study were (a) to linguistically and culturally adapt the English bedside version of the Western Aphasia Battery-Revised (Bedside WAB-R) into Moroccan Arabic (MA) and (b) to assess its psychometric properties. METHOD: The Bedside MA-WAB-R was piloted on a population of 20 participants after a process of linguistic adaptation from English to MA. To verify the psychometric properties of the test, a group of healthy controls (n = 106) and a group of persons with chronic aphasia (n = 52) completed the Bedside MA-WAB-R. The test's content validity, construct validity, and the concurrent validity of the aphasia classification system were examined. In addition, the interrater reliability, intrarater reliability, test-retest reliability, and internal consistency of the instrument were evaluated. RESULTS: The results indicated that the Bedside MA-WAB-R overall met standard criteria for excellent psychometric properties, as evinced by high content and construct validity and concurrent validity with independent measures of aphasia diagnosis (speech-language pathologists' impression and lesion location) as well as high internal consistency, inter- and intrarater reliability, and test-retest reliability. The test was also found to have very high sensitivity and specificity for the detection of aphasia, as revealed by the performance of controls. By controlling for age and educational level effects, specific cutoff values were determined to optimize the aphasia diagnosis. CONCLUSIONS: The Bedside MA-WAB-R is the first standardized quick aphasia assessment tool with associated psychometric properties for clinical use with an MA-speaking population, particularly within the 26- to 58-year age range. It meets standard criteria for a valid and reliable measure than can have a variety of clinical and research applications.

The adaptation of the Object and Action Naming Battery into Moroccan Arabic: Norms for name agreement, frequency, imageability, visual complexity, and age of acquisition.

INTRODUCTION: The ability to name pictures has been investigated widely in healthy people and clinical populations. The Object and Action Naming Battery (OANB) is widely used for psycholinguistic research, aphasia research, and clinical practice. Normative databases for pictorial stimuli have been conducted in language processing studies to control for various psycholinguistic variables known to affect the availability of picture names. The present study provides Moroccan Arabic norms for name agreement, familiarity, imageability, visual complexity, and age of acquisition for 100 line drawings of actions and 162 line drawings of objects taken from Druks and Masterson. METHODS AND PROCEDURES: 160 healthy Moroccan Arabic-speaking individuals participated in this study. Name agreement values for the OANB items were collected from forty subjects, followed by collecting data for the psycholinguistic variables: spoken-word frequency, imageability, visual complexity, and age of acquisition from 120 participants. RESULTS: The Moroccan Arabic OANB (MA-OANB) comprises 70 objects and 60 action pictures. 77% of the nouns and 68% of the verbs obtained 100% target responses. A minimum of 93 percent name agreement was reached for the remaining items. Norms were also collected for the following psycholinguistic variables: spoken-word frequency, imageability, age of acquisition, and visual complexity. CONCLUSION: The stimuli can be used for various psycholinguistic investigations and also for assessment and therapeutic purposes in Morocco.

Cross-cultural adaptation of the Moroccan version of the Mini-Mental State Examination: A preliminary study.

INTRODUCTION: The Mini-Mental State Examination (MMSE) is widely used for dementia screening. The purpose of this study was twofold. First, to cross-culturally adapt the Moroccan Arabic version of MMSE (MA-MMSE) to screen dementia among literate and illiterate elderly Moroccans, and second to analyze its psychometric properties. METHODS: The MA-MMSE was administered to 80 elderly patients, 28 were females and 52 were males. Among all the participants, 22 showed evidence of dementia. Receiver Operator Characteristic (ROC), internal consistency, and test-retest reliability were investigated. The test-retest reliability was assessed by Spearman correlation analysis. Cronbach's α coefficients for internal consistency between total scores and subscores of the test were calculated. RESULTS: Areas under the ROC curve in literate and illiterate elderly Moroccans participants corresponded to 0.932 and 0.936, respectively. The cutoff point of 21/22 on the MA-MMSE in literate elderly had the highest sensitivity (85.7%), specificity (94.7%), and a positive likelihood ratio of (16.29%), whereas the cutoff point of 18/19 of the screening test in illiterate elderly yielded the highest sensitivity (92.9%), specificity (95.0%), and a positive likelihood ratio of (18.57%). The Cronbach's α values of the MA-MMSE for literate and illiterate elderly Moroccans were higher than 0.7. Thirty subjects were randomly selected for participation in the test-retest protocol. Participants were retested after an interval of 4-6 weeks. The test-retest reliability for total scores was significant 0.78 (p < 0.01). CONCLUSION: The findings provide preliminary evidence that the MA-MMSE is a feasible instrument for dementia screening.