Attention-Assisted Feature Comparison and Feature Enhancement for Class-Agnostic Counting.

In this study, we address the class-agnostic counting (CAC) challenge, aiming to count instances in a query image, using just a few exemplars. Recent research has shifted towards few-shot counting (FSC), which involves counting previously unseen object classes. We present ACECount, an FSC framework that combines attention mechanisms and convolutional neural networks (CNNs). ACECount identifies query image-exemplar similarities, using cross-attention mechanisms, enhances feature representations with a feature attention module, and employs a multi-scale regression head, to handle scale variations in CAC. ACECount's experiments on theFSC-147 dataset exhibited the expected performance. ACECount achieved a reduction of 0.3 in the mean absolute error (MAE) on the validation set and a reduction of 0.26 on the test set of FSC-147, compared to previous methods. Notably, ACECount also demonstrated convincing performance in class-specific counting (CSC) tasks. Evaluation on crowd and vehicle counting datasets revealed that ACECount surpasses FSC algorithms like GMN, FamNet, SAFECount, LOCA, and SPDCN, in terms of performance. These results highlight the robust dataset generalization capabilities of our proposed algorithm.

Hierarchical Morphing Control of an Ultra-Lightweight Electro-Actuated Polymer Telescope with Thin-Film Actuators.

This paper explores advanced shape control techniques for ultra-lightweight electro-actuated polymers with composite ferroelectric thin films. It begins with an overview of PVDF-TrFE film actuators used in the development of thin-shell composites, emphasizing the need to overcome constraints related to the electrode size for successful scalability. Strain generation in thin-film actuators is investigated, including conventional electrode-based methods and non-contact electron flux excitation. Numerical studies incorporate experimentally calibrated ferroelectric parameters, modeling non-contact actuation with an equivalent circuit representation. The potential distribution generated by electron flux injection highlights its potential for reducing print-through actuation issues. Additionally, the paper outlines a vision for the future of large thin-shell reflectors by integrating the discussed methods for charging ferroelectric polymer films. A hierarchical control strategy is proposed, combining macro- and micro-scale techniques to rectify shape errors in lightweight reflectors. These strategies offer the potential to enhance precision and performance in future spaceborne observation systems, benefiting space exploration and communication technologies.

Neuro-11: a new questionnaire for the assessment of somatic symptom disorder in general hospitals.

Background: Somatic symptom disorder (SSD) commonly presents in general hospital settings, posing challenges for healthcare professionals lacking specialised psychiatric training. The Neuro-11 Neurosis Scale (Neuro-11) offers promise in screening and evaluating psychosomatic symptoms, comprising 11 concise items across three dimensions: somatic symptoms, negative emotions and adverse events. Prior research has validated the scale's reliability, validity and theoretical framework in somatoform disorders, indicating its potential as a valuable tool for SSD screening in general hospitals. Aims: This study aimed to establish the reliability, validity and threshold of the Neuro-11 by comparing it with standard questionnaires commonly used in general hospitals for assessing SSD. Through this comparative analysis, we aimed to validate the effectiveness and precision of the Neuro-11, enhancing its utility in clinical settings. Methods: Between November 2020 and December 2021, data were collected from 731 patients receiving outpatient and inpatient care at Shenzhen People's Hospital in China for various physical discomforts. The patients completed multiple questionnaires, including the Neuro-11, Short Form 36 Health Survey, Patient Health Questionnaire 15 items, Hamilton Anxiety Scale and Hamilton Depression Scale. Psychiatry-trained clinicians conducted structured interviews and clinical examinations to establish a gold standard diagnosis of SSD. Results: The Neuro-11 demonstrated strong content reliability and structural consistency, correlating significantly with internationally recognised and widely used questionnaires. Despite its brevity, the Neuro-11 exhibited significant correlations with other questionnaires. A test-retest analysis yielded a correlation coefficient of 1.00, Spearman-Brown coefficient of 0.64 and Cronbach's α coefficient of 0.72, indicating robust content reliability and internal consistency. Confirmatory factor analysis confirmed the validity of the three-dimensional structure (p<0.001, comparative fit index=0.94, Tucker-Lewis index=0.92, root mean square error of approximation=0.06, standardised root mean square residual=0.04). The threshold of the Neuro-11 is set at 10 points based on the maximum Youden's index from the receiver operating characteristic curve analysis. In terms of diagnostic efficacy, the Neuro-11 has an area under the curve of 0.67. Conclusions: (1) The Neuro-11 demonstrates robust associations with standard questionnaires, supporting its validity. It is applicable in general hospital settings, assessing somatic symptoms, negative emotions and adverse events. (2) The Neuro-11 exhibits strong content reliability and validity, accurately capturing the intended constructs. The three-dimensional structure demonstrates robust construct validity. (3) The threshold of the Neuro-11 is set at 10 points.

Shape Control of a Unimorph Deformable Mirror for Space Active Optics under Uncertainties.

This paper focuses on the change of morphing capabilities for a unimorph deformable mirror impacted by environmental factors, which works in space for active optics applications. Various aspects of disturbing sources are considered, including complex thermal and mechanical conditions on ferroelectric behaviours of strain actuation, and influences of preconfigured initial shapes and stress-induced geometric stiffness on the structural rigidity of the mirror; changes on both the perturbed shape and the Jacobian matrix are discussed. Those variations are regarded as uncertainties in the design of control methods with both open-loop and iterative control strategies tested in the quasi-static range.

Comparison of treatments with ordinal responses in trials with sequential monitoring and response-adaptive randomization.

In clinical trials, comparisons of treatments with ordinal responses are frequently conducted using the proportional odds model. However, the use of this model necessitates the adoption of the proportional odds assumption, which may not be appropriate. In particular, when responses are skewed, the use of the proportional odds model may result in a markedly inflated type I error rate. The latent Weibull distribution has recently been proposed to remedy this problem, and it has been demonstrated to be superior to the proportional odds model, especially when response-adaptive randomization is incorporated. However, there are several drawbacks associated with the latent Weibull model and the previously suggested response-adaptive treatment randomization scheme. In this paper, we propose the modified latent Weibull model to address these issues. Based on the modified latent Weibull model, the original response-adaptive design was also revised. In addition, the group sequential monitoring mechanism was included to enable interim analyses to be performed to determine, during a trial, whether a specific treatment is significantly more effective than another. If so, this will enable the trial to be terminated at a much earlier stage than a trial based on a fixed sample size. We performed a simulation study that clearly demonstrated the merits of our proposed framework. Furthermore, we redesigned a clinical study to further illustrate the advantages of our response-adaptive approach.

Mini-Implant-Retained Overdentures for the Rehabilitation of Completely Edentulous Maxillae: A Systematic Review and Meta-Analysis.

PURPOSE: Mini-dental implants (MDIs) have been used to support and retain overdentures, providing patients with a less invasive placement procedure. Although lucrative, the use of MDIs to retain a maxillary overdenture is still not an established treatment modality. This systematic review aims to answer the question: Do mini-implant-retained maxillary overdentures provide a satisfactory treatment outcome for complete edentulism? METHODS: A systematic search for relevant articles was conducted to include articles published until April 2021 in the following electronic databases: CINAHL, Cochrane, EMBASE, PubMed, and Web of Science. All empirical studies evaluating the biological, survival, or patient-reported outcomes after placing mini-implant-retained overdentures in maxilla were considered for inclusion. The risk of bias was assessed by utilizing the Joanna Briggs Institute critical appraisal checklist. Study screening and data extraction were conducted by three reviewers independently. RESULTS: The electronic search retrieved 1276 titles after omitting duplicates. Twenty articles were considered for full-text review, of which six studies were included in this systematic review. The included studies evaluated a total of 173 participants with a mean age of 66.3 years. The overall mini-implant survival rate was 77.1% (95% CI: 64.7-89.5%) with a mean follow-up time of 1.79 years (range: 6 months to 3 years). Implant survival differed significantly when comparing complete and partial palatal coverage overdentures. Those with complete palatal coverage exhibited less bone loss overall compared to partial coverage overdentures. Participants of all studies reported an increase in the quality of life and in satisfaction after rehabilitation treatment with MDIs. CONCLUSIONS: The survival rate of mini-implants retaining an overdenture in the maxilla was observed to be lower than the values reported for traditional implants in the literature. Improvements were observed in all aspects in terms of patient satisfaction, quality of life, oromyofunction, and articulation after the treatment.

Practice and discussion on children health communicationin public health emergencies / 中国学校卫生

Abstract@#In public health emergencies, children, as vulnerable groups, face more risks of lack of rights. Reasonable health communication can help protect children’s rights. Taking the COVID-2019 epidemic as an example, using children’s rights as the framework, and based on the classic "5W" theory of communication,this article systematically sorts out the diversity of the main body that propagate children health,the value of children ’s rights (49%) emphasized in the communication contents and the entire media characteristics highlighted in the communication channels after combing the relevant information about children found by the administrative media of China’s health and education administrative departments, some children’s related agencies, and the mainstream social media from January 22 to April 28 after the situation of some children infected in the epidemic was found.However, the importance of children as communication object was not enough(3%), and the communication effect had undergone a transition from negative to positive. Moreover, it also calls on children’s health communication institutions to pay attention to protecting children’s rights, improving their ability of propagate children’s health knowledge to the public and quality as medium.

Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway.

Gut-derived 5-hydroxytryptamine (5-HT) is well known for its role in mediating colonic motility function. However, it is not very clear whether brain-derived 5-HT is involved in the regulation of colonic motility. In this study, we used central 5-HT knockout (KO) mice to investigate whether brain-derived 5-HT mediates colonic motility, and if so, whether it involves oxytocin (OT) production in the hypothalamus and OT receptor in the colon. Colon transit time was prolonged in KO mice. The OT levels in the hypothalamus and serum were decreased significantly in the KO mice compared to wild-type (WT) controls. OT increased colonic smooth muscle contraction in both KO and WT mice, and the effects were blocked by OT receptor antagonist and tetrodotoxin but not by hexamethonium or atropine. Importantly, the OT-induced colonic smooth muscle contraction was decreased significantly in the KO mice relative to WT. The OT receptor expression of colon was detected in colonic myenteric plexus of mice. Central 5-HT is involved in the modulation of colonic motility which may modulate through its regulation of OT synthesis in the hypothalamus. Our results reveal a central 5-HT - hypothalamus OT - colonic OT receptor axis, providing a new target for the treatment of brain-gut dysfunction.