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1.
Ann Clin Microbiol Antimicrob ; 10: 38, 2011 Dec 16.
Artigo em Inglês | MEDLINE | ID: mdl-22177310

RESUMO

BACKGROUND: Training of infectious disease (ID) specialists is structured on classical clinical microbiology training in Turkey and ID specialists work as clinical microbiologists at the same time. Hence, this study aimed to determine the clinical skills and knowledge required by clinical microbiologists. METHODS: A cross-sectional study was carried out between June 1, 2010 and September 15, 2010 in 32 ID departments in Turkey. Only patients hospitalized and followed up in the ID departments between January-June 2010 who required consultation with other disciplines were included. RESULTS: A total of 605 patients undergoing 1343 consultations were included, with pulmonology, neurology, cardiology, gastroenterology, nephrology, dermatology, haematology, and endocrinology being the most frequent consultation specialties. The consultation patterns were quite similar and were not affected by either the nature of infections or the critical clinical status of ID patients. CONCLUSIONS: The results of our study show that certain internal medicine subdisciplines such as pulmonology, neurology and dermatology appear to be the principal clinical requisites in the training of ID specialists, rather than internal medicine as a whole.


Assuntos
Educação Médica Continuada/métodos , Educação Médica Continuada/organização & administração , Infectologia/educação , Microbiologia/educação , Avaliação das Necessidades , Encaminhamento e Consulta , Estudos Transversais , Dermatologia/métodos , Humanos , Neurologia/métodos , Pneumologia/métodos , Turquia
3.
Int J Antimicrob Agents ; 23(1): 92-4, 2004 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-14732321

RESUMO

The in vitro effects of levofloxacin and vancomycin in combination were evaluated against high level aminoglycoside-resistant (HLAR) enterococci using chequerboard and time-kill curve techniques. We examined 28 strains of enterococci comprising 17 Enterococcus faecalis, 10 E. faecium and one E. durans. The combination of vancomycin and levofloxacin had indifferent activity against all isolates according to chequerboard microdilution method, but was synergistic for two isolates, one E. faecium and one E. faecalis, using the time-kill curve method. Both strains were levofloxacin resistant and had high level aminoglycoside resistance to gentamicin and streptomycin. Antagonism was not detected in any strain. The results of this study suggested that the combination of vancomycin with levofloxacin does not often show synergistic effect against high level aminoglycoside-resistant enterococci.


Assuntos
Farmacorresistência Bacteriana , Enterococcus faecalis/efeitos dos fármacos , Enterococcus faecium/efeitos dos fármacos , Levofloxacino , Ofloxacino/farmacologia , Vancomicina/farmacologia , Aminoglicosídeos , Quimioterapia Combinada , Enterococcus faecalis/isolamento & purificação , Enterococcus faecium/isolamento & purificação , Técnicas In Vitro , Resistência beta-Lactâmica
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