1.
Bioorg Med Chem Lett
; 20(20): 6149-51, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20813524
RESUMO
Dihydro-resveratrol (dihydro-R), a prominent polyphenol component of red wine, has a profound proliferative effect on hormone-sensitive tumor cell lines such as breast cancer cell line MCF7. We found a significant increase in MCF7 tumor cells growth rates in the presence of picomolar concentrations of this compound. The proliferative effect of dihydro-R was not observed in cell lines that do not express hormone receptors (MDA-MB-231, BT-474, and Ð-562).