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1.
West Afr J Med ; 38(12): 1224-1230, 2021 Dec 30.
Artigo em Inglês | MEDLINE | ID: mdl-35037625

RESUMO

BACKGROUND: Renal Ultrasound Scan (RUS) is known to have an important role in assessing kidney function in healthy people and people with Chronic Kidney Disease (CKD) with the kidney length (KL) being the most commonly used measure. The Glomerular Filtration Rate (GFR) is the gold standard in kidney function assessment and its strength of correlation with a RUS measure is used in ascertaining the reliability of that RUS measure. OBJECTIVES: To compare the strength of correlations between the GFR and RUS measures like KL and cortical thickness (CT) in healthy people and people with CKD. METHODS: One hundred and forty study participants who had kidney ultrasound scan were studied. Creatinine based GFR was determined and linear correlation coefficients (r) were used to determine the relationship between the GFR and RUS measures. RESULTS: Seventy CKD cohorts with stage 2-4 disease and 70 healthy volunteers (each with 35 males and 35 females) took part. The total mean eGFR, KL and CT for the study participants were 70.5 ± 12.5ml/min, 10.0 ± 3.1cm, and 8.6 ± 2.7mm respectively. There was a progressive decline in eGFR and renal CT as CKD worsened down the stages. The mean eGFR, KL and CT of the CKD cohorts were 44.7 + 3.6 ml/min, 9.1 + 3.3 cm and 7.4 + 2.4 mm respectively. Among the CKD cohorts, the eGFR was highest in CGN and, the KL and CT were highest in obstructive uropathy. The GFR, was positively correlated with KL and CT, the strength of association being more with the CT. The mean age and GFR independently predicted the kidney cortical thickness. CONCLUSION: Kidney sizes were smaller in females, with aging and with declining kidney function. The CT being more positively correlated with GFR than the KL, is a more reliable RUS measure in assessing kidney function.


CONTEXTE: On sait que l'échographie rénale (ÉR) joue un rôle important dans l'évaluation de la fonction rénale chez les personnes en santé et chez les personnes atteintes d'insuffisance rénale chronique (IRC) avec la longueur des reins (KL) étant la mesure la plus couramment utilisée. Le débit de filtration glomérulaire (DFG) est l'étalon-or de l'évaluation de la fonction rénale et la force de sa corrélation avec une mesure RUS est utilisée pour déterminer la fiabilité de cette mesure RUS. OBJECTIFS: Comparer la force des corrélations entre le DFG et les mesures de l'ÉRU comme le KL et l'épaisseur corticale (EC) chez des personnes en bonne santé et des personnes atteintes d'IRC. MÉTHODES: Cent quarante participants à l'étude ayant subi une échographie rénale ont été étudiés. Le DFG basé sur la créatinine a été déterminé et des coefficients de corrélation linéaire (r) ont été utilisés pour déterminer la relation entre le DFG et les mesures de RUS. RÉSULTATS: Soixante-dix cohortes d'IRC avec une maladie de stade 2-4 et 70 volontaires sains (35 hommes et 35 femmes) ont participé à l'étude. Les moyennes totales du DFGe, du KL et du CT pour les participants à l'étude étaient respectivement de 70,5 ± 12,5 ml/min, 10,0 ± 3,1 cm et 8,6 ± 2,7 mm respectivement. On a constaté un déclin progressif du DFGe et du CT rénal au fur et à mesure de l'aggravation de l'IRC. Le DFGe moyen, le KL et le CT des cohortes d'IRC étaient de 44,7 + 3,6 ml/min, 9,1 + 3,3 cm et 7,4 + 2,4 mm respectivement. Parmi les cohortes d'IRC, le DFGeT était le plus élevé dans la NGC et le KL et le CT étaient les plus élevés dans l'uropathie obstructive.Le DFG était positivement corrélé avec le KL et le CT. La force de l'association étant plus importante avec le CT. L'âge moyen et le GFR prédisent indépendamment l'épaisseur corticale des reins. CONCLUSION: La taille des reins est plus petite chez les femmes, avec le vieillissement et le déclin de la fonction rénale. Le CT étant plus corrélée plus positivement avec le DFG que le KL, est une mesure plus fiable de l'EFR pour évaluer la fonction rénale. MOTS CLÉS: Taux de filtration glomérulaire, longueur du rein, épaisseur de la corticale.


Assuntos
Insuficiência Renal Crônica , Creatinina , Feminino , Taxa de Filtração Glomerular , Humanos , Rim/diagnóstico por imagem , Masculino , Insuficiência Renal Crônica/diagnóstico por imagem , Reprodutibilidade dos Testes
2.
Pak J Biol Sci ; 16(7): 325-31, 2013 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-24498799

RESUMO

This study was conducted to determine the effect of feeding three differently processed mixtures on health status of broilers. A total of 1080 day-old Marshal broilers were fed; discarded vegetable-fresh bovine blood-fresh rumen digesta (P1), discarded vegetable-ensiled bovine blood-fresh rumen digesta (P2) and discarded vegetable-fresh bovine blood-ensiled rumen digesta (P3) at three levels of inclusion (0, 3 and 6%). Data on blood parameters was taken and were subjected to 3 x 3 factorial arrangements in a completely randomized design. Birds fed P1 had least values (p < 0.05) of serum glucose, total protein, globulin, uric acid and creatinine at starter phase. Birds fed diets containing 3 and 6% level of inclusion recorded the highest (p < 0.05) Packed cell volume, Haemoglobin, White blood cell and Red blood cell values. However, those fed at 0% level of inclusion recorded the highest albumin value. At finisher phase, birds fed P2 and P3 had the highest glucose, uric acid and creatinine values. 6% level of inclusion significantly (p < 0.05) increased the total protein and albumin values. Therefore, for enhanced performance and without comprising the health condition of birds; broiler chickens could be fed diets containing discarded vegetable-fresh bovine blood-ensiled rumen digesta (P3) up to 6% level of inclusion.


Assuntos
Ração Animal , Fenômenos Fisiológicos da Nutrição Animal , Estado Nutricional , Valor Nutritivo , Aves Domésticas/metabolismo , Rúmen/metabolismo , Verduras/metabolismo , Resíduos , Animais , Biomarcadores/sangue , Digestão , Testes Hematológicos , Avaliação Nutricional , Aves Domésticas/sangue , Aves Domésticas/crescimento & desenvolvimento
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