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Nucleic Acids Res ; 46(D1): D802-D808, 2018 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-29092050

RESUMO

Ensembl Genomes (http://www.ensemblgenomes.org) is an integrating resource for genome-scale data from non-vertebrate species, complementing the resources for vertebrate genomics developed in the Ensembl project (http://www.ensembl.org). Together, the two resources provide a consistent set of programmatic and interactive interfaces to a rich range of data including genome sequence, gene models, transcript sequence, genetic variation, and comparative analysis. This paper provides an update to the previous publications about the resource, with a focus on recent developments and expansions. These include the incorporation of almost 20 000 additional genome sequences and over 35 000 tracks of RNA-Seq data, which have been aligned to genomic sequence and made available for visualization. Other advances since 2015 include the release of the database in Resource Description Framework (RDF) format, a large increase in community-derived curation, a new high-performance protein sequence search, additional cross-references, improved annotation of non-protein-coding genes, and the launch of pre-release and archival sites. Collectively, these changes are part of a continuing response to the increasing quantity of publicly-available genome-scale data, and the consequent need to archive, integrate, annotate and disseminate these using automated, scalable methods.


Assuntos
Archaea/genética , Bactérias/genética , Bases de Dados Genéticas , Bases de Dados de Proteínas , Eucariotos/genética , Genômica , Sequência de Aminoácidos , Animais , Sequência de Bases , Mineração de Dados , Previsões , Genoma , Anotação de Sequência Molecular , RNA/genética , Interface Usuário-Computador
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