[Asymptomatic electrocardiographic abnormalities during antiblastic chemotherapy]. / Anomalie elettrocardiografiche asintomatiche in corso di chemioterapia antiblastica.

In patients under antiblastic treatment electrocardiographic abnormalities without subjective symptomatology were observed. The genesis of these abnormalities is discussed in the light of wath is known from the literature. Periodical electrocardiographic control of patients treated with antiblastic drugs is highly recommended.

[Evaluation of erythrocyte deformability in subjects with essential arterial hypertension]. / Valutazione della deformabilità eritrocitaria in soggetti con ipertensione arteriosa essenziale.

Red blood cell filtration rate was studied in patients with essential hypertension selected according to the homogeneity of parameters which could interfere with such a test. An increase of filtration time in control subjects was put in evidence both in patients without vascular complications and in patients with cerebrovascular diseases; no significant difference was seen between the two groups. The red cell filterability behavior can be correlated to hypertension and is an expression of red cell deformability alterations. The variation of this hemorheological parameter could be better defined by an improvement of the red cell filterability test and by further studies on the membrane function in essential hypertension.

[On some aspects of activation of tissue lipolysis by mechanical factors]. / Su alcuni aspetti della attivazione della lipolisi tessutale da parte di fattori meccanici

An analysis of the effect of the ordinary physical factors acting on living beings on the splitting of adipose tissue triglycerides is reported. Massage was usually responsible for activation of lipolysis, or at least for an increase in blood glycerol and NEFA. If carried out for some time and repeated over a period of days, it appears capable of maintaining chronically enhanced lipolysis. The possible causes of these effects are discussed and particular stress is laid on the release of catecholamines by tissue nerve endings. Partial confirmation of this can be seen in the fact that activation of lipolysis can be depressed by administering beta-blocking drugs. The data also suggest that non-neuroendocrine mechanisms may exert a more immediate action on cell metabolism. Such mechanisms are concerned with a sector of cell life about which little is yet known, wherein every biological process is the result of phenomenon dependent on molecular physics.

[On some aspects of activation of tissue lipolysis by electric factors]. / Su alcuni aspetti della attivazione della lipolisi tessutale da parte di fattori elettrici

Like mechanical stimulation, electrical stimulation can nearly always activate lipolysis, as evidenced by increased blood glycerol and NEFA. The interpretation of this phenomenon is discussed and importance is attached to catecholamine mediation, since administration of a beta-blocking agent is sufficient to cause a significant reduction in the extent of the phenomenon. Other mechanisms can possibly be sought in the muscle fibres present in subcutaneous tissue, whose contraction induces increases blood lymph flow. While electrical stimulation of adipose tissue fragments in vitro gave no appreciable results, it is still possible that electrical impulses act even more intimately by means of direct physical modification of the more elementary metabolic mechanisms.