1.
Dalton Trans
; 45(45): 18079-18083, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27805196
RESUMO
A Ru(ii) arene complex with a NO-releasing 4-nitrooxymethyl-pyridine ligand shows increased cytotoxicity against the non-small cell lung cancer cell line A549 as compared to either the free ligand or the unfunctionalized complex. EPR spin-trapping studies show that NO release is selective, being limited in phosphate buffered saline or human serum, but promoted by glutathione.