[The rehabilitative period of ischemic stroke (peculiarities of interhemispheric asymmetry)].

Eighty-five patients, aged 49-63 years, with an ischemic damage of a brain hemisphere have been studied. Interhemispheric asymmetry has been assessed using EEG. The results revealed that a magnitude of interhemispheric asymmetry decreased by the damage of the left hemisphere. In the occipital areas, its magnitude changed in the presence of the ischemic focus in the right hemisphere. The character of interhemispheric interaction in the ventral and dorsal cortex is believed to be a consequence of the development of new structural and functional relations realized as a result of plastic reorganization of its systems.

[Hormonal shifts in chronic hepatic diseases].

The authors offer quantitative evaluation of system cooperation of endocrine functions in healthy individuals, and apply a system approach to diagnostics of chronic liver diseases. The study included analysis of rectilinear and curvilinear correlations between endocrine system parameters in healthy individuals, and shifts in the levels of multilateral associations between the concentrations of various hormones in patients with different degree of the pathologic process in the liver. The study revealed system disintegration which occurs in the organism in cases of liver involvement and found that all liver diseases are associated with pronounced shifts in the condition of the hormonal system. The authors recommend distinguishing certain bands of the functional condition of the organism, which would allow determination of health status, risk groups, presence and prognosis of an illness. Analysis of hormonal status revealed elevation of excessiveness coefficient in liver diseases. The study established parameters that do not only allow quantitative evaluation of system disintegration of the endocrine system functioning, but differentiation of these diseases as well. The results suggest that cooperation of hormonal functions and their intermodal stability underlie the functional condition of both the endocrine system and the entire organism. Integral indices, unlike qualitative characteristics of individual functions, possess high diagnostic and prognostic relevance.

[Transcranial electrostimulation combined with dalargin ultraphonophoresis in the treatment of patients with chronic idiopathic eczema].

General condition and local status were analysed in patients with chronic idiopathic eczema before the conventional treatment and combined therapy including sessions of transcranial electrostimulation and dalargin phonophoresis and after these treatments. The latter combination improved the patients' quality of life and promoted their faster recovery.

[Neuropsychological risk factors of ischemic heart disease]. / Neiropsikhologicheskie faktory riska razvitiia ishemicheskoi bolezni serdtsa.

Based on Merlin's concept of integrative individuality, the following individual levels in types A and type B behavior were studied: psychological (character, locus of subjective control), psychophysiological (temperament, emotionality, psychomotor activity) and neurophysiological (behavioral, electrocortical, and vegetative activations). The distinction in the character and temperament parameters between both of behavior patterns was prevalent. Several accentuated profiles of type A persons behavior were established according to the individual combination of the character and temperament indices. The profile that combined emotionality and activity ("passionate") was confirmed as a behavioral risk factor in the group of the patients with ischemic heart disease. A new test for differential evaluation of psychophysiological profiles of type A behavior was developed and standardized. In the clinical part of the investigation it was the most effective in revealing the psychological risk factor in patients with ischemic heart disease.

[The functional interrelationships of the components of the gastroduodenal complex and its afferent reactions]. / Funktsional'nye vzaimootnosheniia komponentov gastroduodenal'nogo kompleksa i ego afferentnye reaktsii.

The study was undertaken to study the functional relations between the overall electric activities of smooth muscles in 3 gastric portions (cardial and pyloric antrums, and the body of the stomach) and that of duodenal muscles during their direct electric stimulation, followed by the recording of potentials evoked in the feline cerebral cortex. There was an ambiguous correlation of the amplitudes of the electric activity of 4 portions of the gastroduodenal complex during opiate receptor activation and after vagotomy. The central and intraorgan components were found to play a combined role in displaying responses of gastroduodenal smooth muscles to opiate receptor stimulation and block.

[The effect of morphine on baseline alcohol motivation in rats]. / Vliianie morfina na iskhodnuiu alkogol'nuiu motivatsiiu u krys.

Morphine was studied for its effects on the baseline alcohol motivation in experiments on ethanol-preferring (EPRs) and -rejecting (ERRs) rats. The intraperitoneal administration of morphine in doses of 0.05 and 1 mg/kg caused an increase in ethanol uptake in EPRs both during administration of morphine and after its discontinuation and did not affect the voluntary consumption of morphine solution. The above doses induced no increases in ethanol uptake in ERRs as compared with the controls and stimulated their voluntary consumption of morphine solution. It is concluded that in EPRs, alcohol motivation is enhanced by morphine and the latter used in a dose of 0.05 mg/kg may cause the withdrawal syndrome in ERRs.

[The effect of transcranial electrostimulation on initial alcoholic motivation in rats]. / Vliianie transkranial'noi élektrostimuliatsii na iskhodnuiu alkogol'nuiu motivatsiiu u krys.

The effect of transcranial electrical stimulation (TES) was found to inhibit alcohol intake in rats used to ethanol, whereas in those unused to ethanol the alcohol intake increased after the TES. The TES effect seems to be connected with the difference in opioid system conditions in animals with different spontaneous alcohol motivation.

[The characteristics of the opioid regulation of the afferent reactions of the stomach and duodenum to the early stages of their acute damage]. / Osobennosti opioidnykh reguliatsii afferentnykh reaktsii zheludka i dvenadtsatiperstnoi kishki na rannikh étapakh ikh ostrogo povrezhdeniia.

Acute cat experiments were conducted to study the effect of naloxone, moradol and dalargin on the formation of afferent reactions of gastroduodenal complex components by registration of cortical and subcortical evoked potentials during electrostimulation of the stomach and duodenum at an early stage of their acute lesion. It is found that agonists and antagonists of opiate receptors prevent the depression of afferentation of gastroduodenal complex components early after acute lesion. It is suggested that the main mechanism underlying the depression of gastric and duodenal afferent reactions at early post-alteration period may be related to activation of intraorganic opioid systems.

[Sensorium function on the eve of physiological labor and labor complicated by uncoordinated uterine contractile activity]. / O funktsional'nom sostoianii sensornoi sfery nakanune fiziologicheskikh rodov i rodov, oslozhnennykh diskoordinirovannoi sokratitel'noi deiatel'nost'iu matki.

Characteristic features of the CNS performance before the labor and their prognostic value are presented in the paper. It has been stated that uncoordinated uterine contractility commonly develops in the presence of a lower performance of visual and auditory analysers and alterations in the sensorium balance.

[Disorders of cardiac rhythm in children with pre- and perinatal damage of the brain]. / Narusheniia serdechnogo ritma u detei s pre- i perinatal'nymi povrezhdeniiami mozga.

Alterations in the cardiac rhythm were analyzed in 108 children with pre- and perinatal hypoxic-traumatic brain injuries. Comparisons were made with the data obtained in a group of 30 normal children. The data of the clinical and electrophysiological assessment of the encephalopathy gravity were correlated with the regularity of the cardiac rhythm: heart rate (HR), mode (M), mode amplitude (MA), variation swing (VS), tension index (TI) according to R. M. Baevsky and redundancy coefficient (RC). It has been established that the encephalopathic children demonstrated an increase in the HR, TI and MA and a fall of the M and VS. The intensity of the alterations under study correlated well with the gravity of pre- and perinatal brain injuries. The TI, MA and R were of the highest diagnostic value. Taking into consideration of the magnitude of cardiac rhythm alterations one can predict neurological sequelae detectable in children aged 2 years.

[Status of the sensory sphere in schizophrenic patients with a cenestopathic-hypochondriacal syndrome]. / Sostoianie sensornoi sfery u bol'nykh shizofreniei s senestopaticheski-ipokhondricheskim sindromom.

The state of and interrelations between the kinesthetic and visual sensitivity were studied in 70 patients and 24 normal subjects by using the technique of parallel-sequential sensometry suggested by A. V. Zavyalov. At 30 sec intervals at the constant baseline irritation, 16 thresholds of weight differentiation and 16 thresholds of brightness differentiation were registered. The results were subjected to the correlational and informational analysis. It was established that hyposensitivity of the sensory systems studied was accompanied with the weakening of direct and strengthening of the inverse optical-kinesthetic correlation, the absence of the functional predominance of the kinesthetic analyzer over the visual one, low orderliness of the parameters of the interanalyzer relationship and a sharp liability of the intersensory correlation to the effect of the heterosensory irritant. Changes in the systemic organization of the sensory sphere seem to be responsible for various cenesthopathies.

[Correlation between acute cerebral circulatory disorders and changes in the earth's magnetic field]. / O korreliatsionnoi sviazi ostrykh narushenii mozgovogo krovoobrashcheniia s izmeneniiami magnitnogo polia zemli.

An analysis of 4023 cases of acute cerebral circulatory impairments (ACCI) recorded in the cities of the Central Russia plateau (Kursk, Belgorod, Orel, Zheleznogorsk) has shown that there is an increase in the incidence of ACCI both upon the onset and the cessation of magnetic storms. An elevated rate of ACCI was observed both at high and low levels of the regional magnetic field tension. Therefore, the authors suggest that while making a regression-correlation analysis by the gradient of the Earth's magnetic field--differential regional K-index, the sign of tension alterations should be left out of account. This makes it possible to elucidate the linear dependence between the ACCI incidence and the differential K-index. Results of analysis are proposed to be used in multivariate statistical investigations with the purpose of medical weather forecasting and the prevention of cardiovascular disease complications.