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1.
J Int Med Res ; 49(2): 300060520985657, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33596689

RESUMO

Small cell carcinoma of the cervix is a rare malignant tumor in the clinical setting. Clinical manifestations of this tumor are mostly similar to those of normal types of cervical cancer. Small cell carcinoma of the cervix only shows symptoms of neuroendocrine tumors, such as syndrome of inappropriate antidiuretic hormone secretion (SIADH). Most of the hyponatremia caused by SIADH can be managed after removal of the cause. Hyponatremia is a predictor of poor prognosis and can be used as an indicator of partial recurrence. We report a case of small cell carcinoma of the cervix complicated by SIADH. Our patient presented with irregular vaginal bleeding after menopause. After one cycle of chemotherapy, there was trembling of the limbs, and a laboratory examination showed low Na+ and low Cl- levels. After limited water intake, intravenous hypertonic saline, and intermittent diuretic treatment, the patient's blood Na+ levels returned to normal. After a radical operation, the above-mentioned symptoms disappeared.


Assuntos
Carcinoma de Células Pequenas , Síndrome de Secreção Inadequada de HAD , Carcinoma de Células Pequenas/complicações , Carcinoma de Células Pequenas/tratamento farmacológico , Colo do Útero , Feminino , Humanos , Síndrome de Secreção Inadequada de HAD/complicações , Recidiva Local de Neoplasia , Neoplasias do Colo do Útero , Vasopressinas
2.
Medicine (Baltimore) ; 97(43): e12698, 2018 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-30412064

RESUMO

RATIONALE: Placental site trophoblastic tumor (PSTT) is a rare form of gestational trophoblastic neoplasm (GTN). PATIENT CONCERNS: A 28-year-old Chinese female with initial presentation of thrombotic microangiopathy (TMA) with symptoms of edema of the lower extremities and eyelid, thrombocytopenia and anemia. DIAGNOSES: The primary diagnosis was chronic glomerulonephritis according to the related laboratory tests and clinical symptoms. INTERVENTIONS: A total abdominal hysterectomy with a bilateral salpingectomy was performed. OUTCOMES: The PSTT patient was cured, which contributed to the symptom relief of TMA. LESSONS: This case report aims to elucidate the relationship between TMA and PSTT, so as to achieve timely diagnosis and treatment and reduce misdiagnosis.


Assuntos
Histerectomia/métodos , Complicações Cardiovasculares na Gravidez , Complicações Neoplásicas na Gravidez , Microangiopatias Trombóticas/etiologia , Tumor Trofoblástico de Localização Placentária/diagnóstico , Neoplasias Uterinas/diagnóstico , Adulto , Cesárea , Feminino , Humanos , Recém-Nascido , Gravidez , Microangiopatias Trombóticas/diagnóstico , Microangiopatias Trombóticas/cirurgia , Tumor Trofoblástico de Localização Placentária/complicações , Tumor Trofoblástico de Localização Placentária/cirurgia , Neoplasias Uterinas/complicações , Neoplasias Uterinas/cirurgia
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