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Biomed Res Int ; 2015: 184845, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26357649

RESUMO

Endocrine disrupting chemicals (EDCs) are chemicals that have the capacity to interfere with normal endocrine systems. Two EDCs, bisphenol A (BPA) and triclosan (TCS), are mass-produced and widespread. They both have estrogenic properties and similar chemical structures and pharmacokinetic features and have been detected in human fluids and tissues. Clinical evidence has suggested a positive association between BPA exposure and implantation failure in IVF patients. Studies in mouse models have suggested that preimplantation exposure to BPA and TCS can lead to implantation failure. This paper reviews the relationship between preimplantation exposure to BPA and TCS and implantation failure and discusses the remaining problems and possible solutions.


Assuntos
Compostos Benzidrílicos/efeitos adversos , Implantação do Embrião/efeitos dos fármacos , Disruptores Endócrinos/efeitos adversos , Exposição Ambiental/efeitos adversos , Fenóis/efeitos adversos , Triclosan/efeitos adversos , Animais , Humanos
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