Assuntos
Bloqueio Cardíaco/terapia , Coração/fisiopatologia , Hemodinâmica , Marca-Passo Artificial , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Coração/diagnóstico por imagem , Bloqueio Cardíaco/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , RadiografiaAssuntos
Acetanilidas/administração & dosagem , Amiodarona/administração & dosagem , Arritmias Cardíacas/tratamento farmacológico , Benzofuranos/administração & dosagem , Infarto do Miocárdio/complicações , Procainamida/administração & dosagem , Quinidina/administração & dosagem , Trimecaína/administração & dosagem , Animais , Complexos Cardíacos Prematuros/tratamento farmacológico , Cães , Quimioterapia Combinada , Feminino , Humanos , MasculinoRESUMO
The efficacy of antiarrhythmic therapy with trimecain in 5 different regimens was studied in 87 patients, in 146 episodes of various disorders of the cardiac rhythm. On the basis of clinical and experimental (on 14 dogs with ventricular arrhythmia) studies, different schemes of trimecain treatment are compared. It was shown that combination of the intravenous and the subsequent intramuscular administration of trimecain to treat ventricular extrasystole complicating the course of acute myocardial infarction is as effective as prolonged instillation but exerts a longer action and is better tolerated by patients. Using tetrapolar chest rheography the effect of trimecain infused in the maximum single dose on the central hemodynamics and the ECG was studied in subjects without any cardiovascular pathology. It has been established that trimecain does not suppress myocardial contractility and has no hypotensive action.