Does Eye Gaze Uniquely Trigger Spatial Orienting to Socially Relevant Information? A Behavioral and ERP Study.

Using behavioral and event-related potential (ERP) measures, the present study examined whether eye gaze triggers a unique form of attentional orienting toward threat-relevant targets. A threatening or neutral target was presented after a non-predictive gaze or an arrow cue. In Experiment 1, reaction times indicated that eye gaze and arrow cues triggered different attention orienting towards threatening targets, which was confirmed by target-elicited P3b latency in Experiment 2. Specifically, for targets preceded by arrow and gaze cues, P3b peak latency was shorter for neutral targets than threatening targets. However, the latency differences were significantly smaller for gaze cues than for arrow cues. Moreover, target-elicited N2 amplitude indicated a significantly stronger cue validity effect of eye gaze than that of arrows. These findings suggest that eye gaze uniquely triggers spatial attention orienting to socially threatening information.

Misaligned dynamic faces are processed holistically.

It was recently proposed that both experience-driven and object-based perceptual grouping contribute to holistic face processing. We investigated whether motion-as a common fate perceptual grouping cue-could enhance the holistic processing of misaligned faces. We manipulated alignment and motion (dynamic and static) of study and test faces in a modified complete composite task in which the congruency effect was regarded as an indicator of holistic processing. Participants made same-different judgments about the top halves of two sequentially presented composite faces. We observed that when the study faces were dynamic, regardless of whether the test faces were dynamic or static, misaligned-misaligned face pairs were processed holistically. When the study faces were static, misaligned-misaligned face pairs showed no holistic processing, and neither did inverted faces. These results indicate that motion can promote the holistic processing of misaligned faces. Our findings provide important insights into different types of holistic face processing, and we discuss these types as well as their relationships with each other in depth.

Trait/Financial Information of Potential Male Mate Eliminates Mate-Choice Copying by Women: Trade-Off Between Social Information and Personal Information in Mate Selection.

Mate-choice copying occurs when people rely on the mate choices of others (social information) to inform their own mate decisions. The present study investigated women's strategic trade-off between such social learning and using the personal information of a potential mate. We conducted two experiments to investigate how mate-choice copying was affected by the personal information (e.g., trait/financial information, negative/positive valence of this information, and attractiveness) of a potential male mate in short-/long-term mate selection. The results demonstrated that when women had no trait/financial information other than photos of potential mates, they showed mate-choice copying, but when women obtained personality trait or financial situation information (no matter negative or positive) of a potential mate, their mate-choice copying disappeared; this effect was only observed for low-attractiveness and long-term potential partners. These results demonstrated human social learning strategies in mate selection through a trade-off between social information and personal information.

Chinese Aesthetic Mask: Three Forehead and Five Eyes-Holistic Processing and Facial Attractiveness.

Human face processing has been attributed to holistic processing. Here, we ask whether humans are sensitive to configural information when perceiving facial attractiveness. By referring to a traditional Chinese aesthetic theory-Three Forehead and Five Eyes-we generated a series of faces that differed in spacing between facial features. We adopted a two-alternative forced-choice task in Experiment 1 and a rating task in Experiment 2 to assess attractiveness. Both tasks showed a consistent result: The faces which fit the Chinese aesthetic theory were chosen or rated as most attractive. This effect of configural information on facial attractiveness was larger for faces with highly attractive features than for faces with low attractive features. These findings provide experimental evidence for the traditional Chinese aesthetic theory. This issue can be further explored from the perspective of culture in the future.

Normality mediates the effect of symmetry on facial attractiveness.

Although symmetry, averageness, and sexual dimorphism are usually considered important to facial attractiveness, there are mixed findings regarding whether and how symmetry influences facial attractiveness. The present study introduced "facial normality" to explain the inconsistency of previous research. We hypothesized that symmetry only increased facial attractiveness when it improved facial normality. We manipulated symmetry and normality simultaneously on sixteen Chinese male faces and asked participants to rate the perceived symmetry, perceived normality, and facial attractiveness. The results demonstrated an interactive effect of symmetry and normality on facial attractiveness. The structural equation model results showed two paths from symmetry to facial attractiveness: (1) Symmetry reduced facial attractiveness by decreasing perceived normality; (2) Symmetry increased facial attractiveness by increasing the perceived symmetry and then improving perceived normality. In other words, perceived normality acted as a mediator between symmetry and facial attractiveness. The present study provides a solution to the different effects of symmetry on facial attractiveness in previous studies and suggests that future studies on symmetry and facial attractiveness should consider the mediating role of normality.

The constancy of the holistic processing of unfamiliar faces: Evidence from the study-test consistency effect and the within-person motion and viewpoint invariance.

It has been well documented that static face processing is holistic. Faces contain variant (e.g., motion, viewpoint) and invariant (race, sex) features. However, little research has focused on whether holistic face representations are tolerant of within-person variations. The present study thus investigated whether holistic face representations of faces are tolerant of within-person motion and viewpoint variations by manipulating study-test consistency using a complete composite paradigm. Participants were shown two faces sequentially and were asked to judge whether the faces' top halves were identical or different. The first face was a static face or a dynamic face rotated in depth at 30°, 60°, and 90°. The second face was either a different front-view static face (Experiment 1a, study-test inconsistent) or identical to the first face (Experiment 1b, study-test consistent). In Experiment 2, study-test consistency was manipulated within subjects, and inverted faces were included. Our results show that study-test consistency significantly enhanced the holistic processing of upright and inverted faces; this study-test consistency effect and holistic processing were not modulated by motion and viewpoint changes via depth rotation. Interestingly, we found holistic processing for moving study-test consistent inverted faces, but not for static inverted faces. What these results tell us about the nature of holistic face representation is discussed in depth with respect to earlier and current theories on face processing.

Self-Construal Priming Affects Holistic Face Processing and Race Categorization, but Not Face Recognition.

Self-construal priming can affect an individual's cognitive processing. Participants who were primed with interdependent self-construal showed more holistic process bias than those who were primed with independent self-construal. The holistic processing of a face also differs across cultures. As such, the purpose of the present study was to explore whether the cultural differences in holistic face processing can be interpreted from the perspective of self-construal, as well as to investigate the relationship between self-construal and holistic face processing/face recognition/race categorization. In Experiment 1, participants were primed with control, interdependent, or independent self-construal, respectively, and then they completed a feature-space same-different task (Experiment 1A) or a composite face effect task (Experiment 1B). Results showed no priming effect in Experiment 1A, whereas independent self-construal priming resulted in less holistic processing in Experiment 1B. In Experiment 2, participants were primed with control, collective/interdependent, relational, or independent self-construal, respectively, and then they completed a Vanderbilt Holistic Face Processing Test and Cambridge Face Memory Test. Participants who were primed as independent showed greater congruency effect than the relational group. Self-construal priming had no effect on face recognition. In Experiment 3, we manipulated self-construal in the same way as that in Experiment 2 and monitored the eye movement of Chinese participants while they learned, recognized, and categorized their own-/other-race faces. Self-construal priming had no effect on face recognition. Compared with other groups, collective-/interdependent-self priming increased the fixation time of eyes and decreased the fixation time of nose in the race categorization task. These results indicated that the cultural differences in self-construal could not mirror the cultural differences in face processing in a simple way.

Ensemble perception of facial attractiveness.

Ensemble perception, the extraction of a statistical summary of multiple instances of a feature, enables efficient processing of information. Here we investigated whether ensemble representations can be formed for facial attractiveness, a socially important complex feature. After verifying that our face stimuli produced by geometric morphing represented a valid continuum of attractiveness (Experiment 1), we asked participants to compare the average attractiveness of four faces with a single probe face. Whether the four faces were homogeneous or heterogeneous resulted in highly similar performance levels, suggesting the visual system could extract an ensemble representation of the attractiveness of a heterogeneous group of faces. Statistical simulations with human-level bias and noise indicated participants did not rely on subsampling one random face or the most/least attractive face from the array (Experiment 2). Ensemble perception of facial attractiveness was not affected by variance in the stimulus array (Experiment 3), did not depend on memory of individual faces in the array (Experiment 4), and could be extended to larger arrays with faces asymmetrically distributed around the set mean (Experiment 5). Our findings give further evidence to the prevalence of perception of statistical regularities in vision.

Attentional modulation of hierarchical ensemble coding for the identities of moving faces.

Observers can accurately compute summary statistics from a set of similar objects, which is referred to as ensemble coding. Few studies have investigated whether ensemble coding can be modulated by attention (i.e., whether attention can be selectively deployed to exclude irrelevant items from the ensemble coding of relevant items), and no studies have tested whether this coding represents the average of a relevant subset, the average of an irrelevant subset, or the average of the entire set. The present study employed an adapted paradigm of the multiple object tracking (MOT) task in which participants viewed multiple moving target faces and were asked to indicate whether a subsequent test face was one of the preceding targets. Experiment 1 showed that ensemble coding occurred for moving faces, and Experiments 2, 3, and 4 showed that participants were more likely to judge the individual and the average of tracked target faces than the average of all (target and nontarget) faces in the display and average nontarget faces. These findings suggest that ensemble coding for facial identities is hierarchical and can, at least partially, be modulated by attention. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Rhein suppresses matrix metalloproteinase production by regulating the Rac1/ROS/MAPK/AP-1 pathway in human ovarian carcinoma cells.

Matrix metalloproteinases (MMPs) are a family of calcium-dependent zinc-containing endopeptidases, which play an integral role in migration and invasion of ovarian cancer. Rac1 proteins might mostly influence cell migration and invasion by generating endogenous reactive oxygen species. Therefore, inhibiting MMPs and regulating the Rac1/ROS/MAPK/AP-1 pathway may be a new therapeutic strategy for ovarian cancer. In this study, we found that rhein could suppress the invasion and migration of SKOV3-PM4 cells with characteristics of directional highly lymphatic metastasis. Phorbol 12-myristate 13-acetate (PMA), which is a Rac1 activator, significantly enhanced the expression levels of MMP-2, -3, -9 and -19 proteins, whereas the results of rhein and Rac1 inhibitor NSC23766 were just the opposite. The inhibitory effects of rhein were associated with the upregulation of tissue inhibitors of metalloproteinase (TIMP)-1, TIMP-2 and NM23-H1. Subsequent mechanism studies revealed that rhein reduce the production of reactive oxygen species (ROS) and lower NADPH oxidase activity. Furthermore, rhein significantly inhibited JNK, AP-1 phosphorylation in the cells treated with PMA. The results obtained from the cells treated with NSC23766 alone or NSC23766 combined with rhein, were consistent with rhein treatment alone. Taken together, these results indicate that rhein may be a potential inhibitor of Rac1 and can inhibit the migration and invasion of SKOV3-PM4 cells through modulating matrix metalloproteinases and RAC1/ROS/MAPK/AP-1 signaling pathway-associated proteins.

Identification of a conserved neutralizing linear B-cell epitope in the VP1 proteins of duck hepatitis A virus type 1 and 3.

Duck virus hepatitis (DVH), mainly caused by duck hepatitis A virus (DHAV), is a severe disease threaten to duck industry and has worldwide distribution. As the major structural protein, the VP1 protein of DHAV is able to induce neutralizing antibody in ducks. In this study, a monoclonal antibody (mAb) 4F8 against the intact DHAV-1 particles was used to identify the possible epitope in the three serotypes of DHAV. The mAb 4F8 had weak neutralizing activities to both DHAV-1 and DHAV-3, and reacted with the conserved linear B-cell epitopes of (75)GEIILT(80) in DHAV-1 VP1 and (75)GEVILT(80) in DHAV-3 VP1 protein, respectively, while not with DHAV-2 VP1. This was the first report about identification of the common conserved neutralizing linear B-cell epitope of DHAV-1 and DHAV-3, which will facilitate understanding of the antigenic structure of VP1 and the serologic diagnosis of DHAV infection.

Own-race faces capture attention faster than other-race faces: evidence from response time and the N2pc.

Studies have shown that people are better at recognizing human faces from their own-race than from other-races, an effect often termed the Own-Race Advantage. The current study investigates whether there is an Own-Race Advantage in attention and its neural correlates. Participants were asked to search for a human face among animal faces. Experiment 1 showed a classic Own-Race Advantage in response time both for Chinese and Black South African participants. Using event-related potentials (ERPs), Experiment 2 showed a similar Own-Race Advantage in response time for both upright faces and inverted faces. Moreover, the latency of N2pc for own-race faces was earlier than that for other-race faces. These results suggested that own-race faces capture attention more efficiently than other-race faces.

Smaller holistic processing of faces associated with face drawing experience.

The type of experience involved with an object category has been regarded as one important factor in shaping of the human object recognition system. Laboratory training studies have shown that different kinds of learning experience with the same set of novel objects resulted in different perceptual and neural changes. Whether this applies to natural real-world objects remains to be seen. We compared two groups of observers who had different learning experiences with faces, using holistic processing as a dependent measure. We found that, while ordinary observers had extensive individuation experience with faces and displayed typical holistic face processing, art students who had acquired additional experience in drawing faces, and thus in attending to parts of a face, showed less holistic processing than did ordinary observers. These results converge with laboratory training studies on the role of type of experience in the development of different perceptual markers for different object categories. It is thus insufficient to categorize expertise simply in terms of object domains (e.g., expertise with faces). Instead, perceptual expertise should be classified in terms of the underlying process or task demand.

Inconsistent individual personality description eliminates the other-race effect.

The present study investigated the effect of individual semantic information displayed simultaneously with faces on the other-race effect. Arbitrary descriptions of the individual personalities of a set of faces were initially evaluated for consistency. Later, 83 naïve participants were allocated to three groups in which they saw faces and consistent, inconsistent, or neutral personality information about each face. Later, they completed a recognition task for the faces. The other-race effect was observed only in the control group and the consistent-information group, but not in the inconsistent-information group. This showed that inconsistent individual semantic information for each face can help to individuate these faces and eliminated the other-race effect.

Interactive processing among parts, configuration, and orientation of complex objects.

The aim of the present study was to investigate whether the representation of parts and the configuration and orientation of complex objects were separate or interdependent. Participants were asked to match parts and configuration of novel 3-D objects with constant or varied features in irrelevant dimensions. The results of both Exp. 1 (sequential matching) and Exp. 2 (simultaneous matching) showed that both sensitivity and response time (RT) of part matching were influenced by whether the irrelevant configuration remained constant or varied. Both sensitivity and RT for configuration matching were affected by the variation of irrelevant parts in Exp. 2, but only sensitivity was affected in Exp. 1. These results demonstrated an interdependent pattern of representations of parts and relations but different interactive patterns in memory and perception. The results of Exp. 3 showed orientation dependency in a configuration-matching task but orientation invariance in a part-matching task. Consistent with a study done in 2000 by Edelman and Intrator, these results suggest an interactive processing between configuration and orientation but an independent processing between the parts and orientation.

Processes underlying the cross-race effect: an investigation of holistic, featural, and relational processing of own-race versus other-race faces.

Adults are often better at recognising own-race than other-race faces. Unlike previous studies that reported an own-race advantage after administering a single test of either holistic processing or of featural and relational processing, we used a cross-over design and multiple tasks to assess differential processing of faces from a familiar race versus a less familiar race. Caucasian and Chinese adults performed four tasks, each with Caucasian and Chinese faces. Two tasks measured holistic processing: the composite face task and the part/whole task. Both tasks indicated holistic processing of own-race and other-race faces that did not differ in degree. Two tasks measured featural and relational processing: the Jane/Ling task, in which same/ different judgments were made about face pairs that differed in features of their spacing, and the scrambled/blurred task, in which test faces were scrambled (isolates memory for components) or blurred (isolates memory for relations). Both tasks provided evidence of an own-race advantage in both featural and relational processing. We conclude that even when adults process other-race faces holistically, other manifestations of an own-race advantage remain.

Repetition blindness for rotated objects.

Repetition blindness (RB) is the finding that observers often miss the repetition of an item within a rapid stream of words or objects. Recent studies have shown that RB for objects is largely unaffected by variations in viewpoint between the repeated items. In 5 experiments, we tested RB under different axes of rotation, with different types of stimuli (line drawings and shaded images, intact and split), using both novel and familiar objects. Although RB was largely viewpoint invariant, in most experiments, RB was reduced for small (0 degrees ) and large (180 degrees ) viewpoint differences relative to intermediate rotations. However, these deviations from invariance were eliminated when object images were split, breaking the holistic coherence of the object. These findings suggest that RB is due mainly to the activation of object representations from local diagnostic features, but can be modulated by priming on the basis of view similarity.

Specificity of face processing without awareness.

The recognition memory for inverted faces is especially difficult when compared with that for non-face stimuli. This face inversion effect has often been used as a marker of face-specific holistic processing. However, whether face processing without awareness is still specific remains unknown. The present study addressed this issue by examining the face inversion effect with the technique of binocular rivalry. Results showed that invisible upright faces could break suppression faster than invisible inverted faces. Nevertheless, no difference was found for invisible upright houses and invisible inverted houses. This suggested that face processing without awareness is still specific. Some face-specific information can be processed by high-level brain areas even when that information is invisible.

Dissociating viewpoint costs in mental rotation and object recognition.

In a mental rotation task, participants must determine whether two stimuli match when one undergoes a rotation in 3-D space relative to the other. The key evidence for mental rotation is the finding of a linear increase in response times as objects are rotated farther apart. This signature increase in response times is also found in recognition of rotated objects, which has led many theorists to postulate mental rotation as a key transformational procedure in object recognition. We compared mental rotation and object recognition in tasks that used the same stimuli and presentation conditions and found that, whereas mental rotation costs increased relatively linearly with rotation, object recognition costs increased only over small rotations. Taken in conjunction with a recent brain imaging study, this dissociation in behavioral performance suggests that object recognition is based on matching of image features rather than on 3-D mental transformations.