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Fetal Pediatr Pathol ; 42(2): 198-206, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36036082

RESUMO

Objective: We reviewed our experience with congenital hepatic hemangiomas (CHH) to assess the effectiveness of our treatment strategies. Methods: Clinical and pathologic features of children with CHH were reviewed. Results: Twenty-two cases of CHH were collected, 17 were resected and 5 were followed until resolution. In 17 with alpha-feto-protein (AFP) levels, 9 were elevated with 5 decreasing to normal before surgery. In six with tumors under 3 cm, five regressed between 1 and 13 months, one required removal 5 years after initial diagnosis. Postoperative histopathology of 17 cases showed abnormal vascular hyperplasia without lobular architecture. CD34 was expressed in all tumors, glucose transporter 1(Glut1) was negative. Conclusion: If the tumor is less than 3 cm, AFP is normal and there are no obvious complications, the lesion can be followed with regular assessment imaging. Surgical resection is an option in tumors less than 3 cm which have not regressed over time.


Assuntos
Hemangioma , Neoplasias Hepáticas , Humanos , Criança , Estudos Retrospectivos , alfa-Fetoproteínas , Hemangioma/patologia , Neoplasias Hepáticas/diagnóstico , Neoplasias Hepáticas/patologia
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