1.
Chem Commun (Camb)
; 46(41): 7834-6, 2010 Nov 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-20830335
RESUMO
We report a mild and environmentally benign method for the synthesis of tertiary amines using alcohols as the alkylating reagents. Not only secondary amines such as piperazines but also amino acids and amino alcohols can be N-alkylated selectively. For N,O-benzyl protected amino alcohols, both N,O-de-benzylation and N-methylation were achieved in one-pot.