Assuntos
Armas Biológicas , Bioterrorismo , Comércio , Internet , Humanos , Sistemas On-Line , RiscoRESUMO
In the run-up to his reelection, Russian president Vladimir Putin outlined 28 tasks to be undertaken by his administration, including one that commanded the development of weapons based on "genetic principles." Political pressure must be applied by governments and professional societies to ensure that there is not a modern reincarnation of the Soviet biological warfare program.
Assuntos
Guerra Biológica/legislação & jurisprudência , Programas Governamentais , Humanos , Federação RussaAssuntos
Armas Biológicas , Toxinas Botulínicas Tipo A/economia , Toxinas Botulínicas , Comércio , Indústria Farmacêutica , Fraude , Armas Biológicas/economia , Armas Biológicas/legislação & jurisprudência , Toxinas Botulínicas/economia , Toxinas Botulínicas/toxicidade , Comércio/legislação & jurisprudência , Enganação , Contaminação de Medicamentos , Internet , Legislação de MedicamentosAssuntos
Biotecnologia/tendências , Engenharia Genética/tendências , Biologia Molecular/tendências , Medição de Risco , Guerra Biológica , Contenção de Riscos Biológicos , DNA Recombinante , Genes Sintéticos , Genômica/tendências , Microbiologia , Biologia Molecular/métodos , Organismos Geneticamente ModificadosRESUMO
This article describes the composition of the Soviet Anti-plague (AP) system and presents the methodology used by the authors in their study of the AP system.
Assuntos
Peste/prevenção & controle , Guerra Biológica , Controle de Doenças Transmissíveis/história , História do Século XX , História do Século XXI , Humanos , Peste/história , U.R.S.S.RESUMO
The USSR possessed a unique national public health system that included an agency named "anti-plague system." Its mission was to protect the country from highly dangerous diseases of either natural or laboratory etiology. During the 1960s, the anti-plague system became the lead agency of a program to defend against biological warfare, codenamed Project 5. This responsibility grew and by the middle 1970s came to include undertaking tasks for the offensive biological warfare program, codenamed Ferment. This article describes the anti-plague system's activities relevant to both aspects of the Soviet Union's biological warfare program, offense and defense, and analyzes its contributions to each.
Assuntos
Guerra Biológica/história , Órgãos Governamentais/história , Peste/história , Administração em Saúde Pública/história , Controle de Doenças Transmissíveis/história , Controle de Doenças Transmissíveis/organização & administração , Surtos de Doenças/história , Surtos de Doenças/prevenção & controle , Órgãos Governamentais/organização & administração , História do Século XX , História do Século XXI , Humanos , Peste/prevenção & controle , Vacina contra a Peste/história , Vacina contra a Peste/uso terapêutico , U.R.S.S.RESUMO
This article analyzes the proliferation challenges posed by the Soviet AP system and discusses possible nonproliferation strategies to prevent these threats.
Assuntos
Guerra Biológica/história , Controle de Doenças Transmissíveis/história , Peste/história , Guerra Biológica/prevenção & controle , Controle de Doenças Transmissíveis/legislação & jurisprudência , Controle de Doenças Transmissíveis/organização & administração , História do Século XX , Humanos , Peste/prevenção & controle , U.R.S.S.RESUMO
Genetically altered microbes are used widely in the conduct of scientific study and have facilitated the development of new medical therapies, preventive strategies, and diagnostic tools. Unfortunately, such organisms may also cause infectious disease outbreaks as a result of accidental or intentional transmission to humans. The unique microbial properties of genetically altered pathogens and the clinical symptoms exhibited by persons infected with them may impede the usual diagnostic and clinical evaluations or preventive strategies. Practicing physicians and clinicians at microbiology laboratories, who would be the first to observe such infections, must consider the broad clinical possibilities of illnesses caused by deliberately altered microorganisms and the potential difficulty in confirming a diagnosis.
Assuntos
Infecções Bacterianas/epidemiologia , Infecções Bacterianas/microbiologia , Surtos de Doenças , Organismos Geneticamente Modificados , Viroses/epidemiologia , Viroses/microbiologia , HumanosRESUMO
In November 2001, the Monterey Institute of International Studies convened a workshop on bioterrorism threat assessment and risk management. Risk assessment practitioners from various disciplines, but without specialized knowledge of terrorism, were brought together with security and intelligence threat analysts to stimulate an exchange that could be useful to both communities. This article, prepared by a subset of the participants, comments on the workshop's findings and their implications and makes three recommendations, two short term (use of threat assessment methodologies and vulnerability analysis) and one long term (application of quantitative risk assessment and modeling), regarding the practical application of risk assessment methods to bioterrorism issues.