Ocular examination findings and selected ophthalmic diagnostic tests in African green monkeys (Chlorocebus aethiops sabaeus).

OBJECTIVE: To document ocular lesions and establish ophthalmic diagnostic test reference values in a colony of African green monkeys (Chlorocebus aethiops sabaeus). ANIMALS STUDIED: Fifty one geriatric (GAGM, 19-30 years old), 10 adult (AAGM, 5-9 years old) and 10 juvenile (JAGM, <2 years old) African green monkeys housed in a single Caribbean research colony. PROCEDURES: Ocular biomicroscopy, indirect fundoscopy, Schirmer tear test (STT), rebound tonometry (TonoVet®) and corneal fluorescein staining were performed. Mixed ANCOVA tests were performed to compare STT and IOP between groups. RESULTS: Common ocular lesions in GAGM included vitreal degeneration (27/51, 51/102 eyes) and cataracts (21/51, 32/102 eyes). Vitreal degeneration was also common in AAGM (8/10, 16/20 eyes) and infrequent in JAGM (3/10, 6/20 eyes). Cataracts were not present in any JAGM or AAGM. All eyes in all three groups had perilimbal corneal pigmentation and faint lace-like anterior corneal stromal opacification. Median (range) STT values were 16.0 (18) mm/min in GAGM. Mean (SD) STT values were 14.2 (4.6) mm/min in AAGM, and 8.9 (3.4) mm/min in JAGM. Median (range) IOP values were 16.5 (27) mmHg in GAGM. Mean (SD) IOP values were 18.0 (2.8) mmHg in AAGM, and 14.1 (2.2) mmHg in JAGM. JAGM had significantly lower STT and IOP values compared to AAGM (p = .0449, .0057, respectively) and GAGM (p = .0002, .0130, respectively). CONCLUSIONS: Spontaneous ocular lesions were common in geriatric monkeys in this research colony. IOP and STT values were lower in juvenile African green monkeys relative to adult or geriatric animals.

Congenital Cataracts and Microphakia with Retinal Dysplasia and Optic Nerve Hypoplasia in a Calf.

Case Description. A two-month-old, female, Aberdeen-Angus calf was presented for congenital cataracts and blindness in both eyes (OU). The dam had a reported history of visual defects (not specified) and had produced other affected calves (per owner history). Ophthalmic examination revealed mature bilateral cataracts, attenuation of the iridic granules, persistent pupillary membranes, and dyscoric pupils. Additionally, the calf had a poor body condition, prognathism, dome-shaped head, excessive nasal drainage, limb contracture, and fever. Histopathology of both eyes revealed lenticular degeneration (congenital cataracts), retinal dysplasia, and optic nerve hypoplasia. BVDV IHC detected antigen within only the left eye (OS), consisting of intrahistiocytic and endothelial immunoreactivity within the ciliary body, iris, and choroid. No BVDV immunoreactivity could be detected in the right eye (OD). This case highlights the unique ocular changes present in in utero BVDV infection of cattle with a different immunohistochemical staining profile than previously described.

Eye removal following parotid duct transposition surgery: A survey of current practice among veterinary ophthalmologists.

OBJECTIVE: Identify dogs that required removal of an eye that had previously undergone a parotid duct transposition (PDT) and secondly to characterize demographics, surgical technique, and outcomes associated with it. PROCEDURE: An online survey was distributed to American College of Veterinary Ophthalmologists (ACVO) and Veterinary Ophthalmology (VOPH) listservs asking members to report the breed, reason for eye removal, time between surgeries, surgical technique, complications, and additional therapy instituted for dogs requiring removal of an eye subsequent to PDT surgery. RESULTS: Sixteen dogs fit the inclusion criteria. Small breeds (<15 kg) made up 80% of the study population. Time between surgeries was <6 months (1/16), 6 to 12 months (7/16), and ≥1 year (8/16). Reasons for eye removal included: advancing corneal disease (6/16), discomfort (6/16), reaction to saliva (4/16), decreased saliva production (2/16), glaucoma (1/16), orbital neoplasia (1/16), and endophthalmitis (1/16). Surgical techniques included: transection of the parotid duct without ligation (2/16), ligation (9/16), and reversal of the PDT with reimplantation into the mouth (5/16). Complications reported were two dogs who underwent duct ligation experienced prolonged dilation of the duct that resolved with medical therapy (1/2) or without additional therapy (1/2). CONCLUSION: Ligation of or reversal of the PDT with reimplantation into the mouth are appropriate adjunctive surgical techniques when removing an eye that previously underwent PDT surgery. Two dogs with nonfunctional PDT had complication-free eye removal with transection without ligation. Prolonged dilation of the duct is possible after eye removal with duct ligation and may resolve with time or medical management.