[Anatomic and functional disorders of the urinary tract in children with urinary tract infections]. / Zaburzenia anatomiczne i czynnosciowe dróg moczowych u dzieci z zakazeniem ukladu moczowego.

The study is based on clinical analysis of 207 case recordings of children with urinary tract infection (UTI) hospitalized in The Department of Pediatric Nephrology, University Hospital, Lublin in 1995-1999. The study comprised children aged 1-18 years, average 8.8 +/- 0.4 (77.8% girls). Recurrent UTI was observed in 76.8% of children. Acute UTI was diagnosed in 20.8% of children. In 2.4% of children UTI was detected during hospitalization because of other diseases. In all children urinary X-ray examination was performed. Anatomical abnormalities were detected in 38% of children. Vesico-ureteral reflux was diagnosed in 61 children (29.5%). In 16/25 (64%) of children with vesico-ureteral reflux renal scarring was detected by radionuclide examination. In some children urodynamic examination was performed and in all of them functional abnormalities were detected.

[Evaluation of oxalate/creatinine ratio in the second morning urine sample of health school children]. / Ocena wskaznika szczawianowo-kreatyninowego w II rannej porcji moczu u zdrowych dzieci w wieku szkolnym.

The evaluation of urinary oxalate excretion is one of the most important diagnostic methods in patients with urolithiasis and/or nephrocalcinosis. Since reliable 24-h urine collections are difficult to obtain in children, excretion ratios of oxalate over creatinine are increasingly being used from single urine specimens. The aim of the study was to determine the normal values of oxalate/creatinine ratios in the second morning urine sample in healthy school children. The study involved 109 children between 6 and 16 years of age. The results showed that the values of Ox/Cr ratios are decreased in older children and there was significant difference between children under and above 12 years of age (values of the 95th percentile--0.076 and 0.051 mmol/mmol respectively). The significant correlation between 24-hours urinary oxalic acid excretions and Ox/Cr ratios (r-0.756) was found. We conclude, that Ox/Cr ratio is valuable parameter for screening purposes in children.

[Influence of glucocorticoid steroid therapy on gastric and duodenal mucosa and Helicobacter pylori infection in children with nephrotic syndrome]. / Wplyw glikokortykosteroidoterapii na blone sluzowa zoladka i dwunastnicy oraz zakazenie Helicobacter pylori u dzieci z zespolem nerczycowym.

UNLABELLED: The purpose of the study was to evaluate the influence of steroid therapy on endoscopic picture of gastric mucosa. The study comprised 22 children (17 boys and 5 girls) with the nephrotic syndrome aged 4-12 years (the mean 9 years) treated with prednisone. Children were divided into two groups taking into account duration of therapy. The group I (10 children) comprised patients with therapy duration not exceeding 3 months. The group II (12 children) comprised children treated 5 years in average. All patients underwent gastroscopic examination. Macro and microscopic lesions of gastric mucosa, their intensity and coexistence of Helicobacter pylori (HP) infection were estimated. CONCLUSIONS: 1. In nephrotic children during prednisone therapy different types of gastric and duodenal mucosal inflammatory changes occur. 2. Duration of prednisone therapy does not influence significantly on location, type and severity of mucosal inflammatory changes. 3. Frequency of coexistent HP infection increases with prednisone therapy duration. 4. Prednisone therapy of nephrotic children is indication for gastric and duodenal endoscopic examination.