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1.
Biull Eksp Biol Med ; 114(9): 329-32, 1992 Sep.
Artigo em Russo | MEDLINE | ID: mdl-1477380

RESUMO

The dynamics of morphologic and biochemical indices of the thyroid gland in puberal rats has been considered. The data obtained suggest that the thymus hormones deficiency in blood circulation after thymectomy affect thyroid-stimulating functions of adenopituitary and thyroliberin production in hypothalamus that results in significant depression of thyroid function, whereas the enhancement of thyroid function to 20-month follow-up has no central genesis but is rather a result of autoimmune processes activation when thymus is removed.


Assuntos
Timectomia , Glândula Tireoide/anatomia & histologia , Glândula Tireoide/fisiologia , Animais , Seguimentos , Hipotálamo/metabolismo , Masculino , Ratos , Timo/fisiologia , Hormônio Liberador de Tireotropina/metabolismo , Fatores de Tempo
2.
Probl Endokrinol (Mosk) ; 38(2): 52-4, 1992.
Artigo em Russo | MEDLINE | ID: mdl-1513776

RESUMO

Morphological changes of the thyroid in non-inbred albino rats were analysed using a complex of histochemical methods. These data show the depression of functional activity against a background of primary immunodeficiency induced by neonatala thymectomy.


Assuntos
Tolerância Imunológica/imunologia , Timo/imunologia , Glândula Tireoide/patologia , Animais , Animais Recém-Nascidos/imunologia , Histocitoquímica , Masculino , Ratos , Timectomia , Glândula Tireoide/fisiologia
4.
Probl Endokrinol (Mosk) ; 37(4): 46-9, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1724083

RESUMO

The time course of structural and functional changes in the parotid and submaxillary salivary glands after neonatal thymectomy was considered. A combination of various methods including histological, histochemical, cytophotometric ones and transmission electron microscopy, was employed. They showed that neonatal thymectomy resulted in an increase in secretory activity of the salivary glands and was followed by hemolymphodynamic disorders and lymphoplasmocytic infiltration.


Assuntos
Glândula Parótida/anatomia & histologia , Glândula Submandibular/anatomia & histologia , Timo/fisiologia , Animais , Animais Recém-Nascidos , DNA/metabolismo , Histocitoquímica , Masculino , Glândula Parótida/metabolismo , RNA/metabolismo , Ratos , Glândula Submandibular/metabolismo , Timectomia , Fatores de Tempo
5.
Biull Eksp Biol Med ; 112(7): 69-72, 1991 Jul.
Artigo em Russo | MEDLINE | ID: mdl-1793862

RESUMO

The dynamics of morphological, enzymatic and immunologic salivary glands indices in pubertal rates was investigated after thymectomy. The data obtained analysis demonstrated the functional salivary glands reconstruction, having immunologic and secretory characteristics: stimulation of the humoral and cellular immunity factors; reduction of the albuminous and rise of the mucous salivary glands component represented the remote effect of thymectomy /3 months]. Activation of the salivary glands immune characteristics may be explained by their belonging to the thymic-peripharyngeal complex.


Assuntos
Glândula Parótida/imunologia , Glândula Submandibular/imunologia , Timectomia , Fosfatase Ácida/análise , Animais , L-Lactato Desidrogenase/análise , Masculino , Glândula Parótida/enzimologia , Glândula Parótida/metabolismo , Ratos , Glândula Submandibular/enzimologia , Glândula Submandibular/metabolismo , Fatores de Tempo
6.
Arkh Patol ; 53(8): 14-6, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1953370

RESUMO

Histological material from 26 patients with laryngeal carcinoma was studied after surgery, photon and remote neutron-photon irradiation. The number of telophases in dividing tumor cells after the mixed irradiation was 1.5-3 times lower as compared to the surgical treatment. This correlated with a significant decrease of the number of cells with high ploidy. It is suggested that the damage to cell cycle occurred after the spin formation, that the parameters studied are sensitive morphological criteria for the diagnosis and prognosis of the tumor cell fate.


Assuntos
Núcleo Celular/efeitos da radiação , DNA de Neoplasias/efeitos da radiação , Neoplasias Laríngeas/ultraestrutura , Mitose/efeitos da radiação , Terapia Combinada , Citofotometria , DNA de Neoplasias/análise , Nêutrons Rápidos , Humanos , Neoplasias Laríngeas/radioterapia , Neoplasias Laríngeas/cirurgia , Cuidados Pré-Operatórios , Radiação , Dosagem Radioterapêutica
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