EUV telescope for a Cubesat nanosatellite.

This paper describes in detail a compact (2U format) telescope operating in the extreme ultraviolet range for studying the solar corona at a wavelength of 17.14 nm. The telescope objective has been built according to the Ritchey-Chrétien scheme with the following parameters: effective focal length of 381.3 mm, field of view of 2×2∘, and angular resolution of 11 in. Reflective multilayer Al/Be coatings were used, having 55% reflectance and a 0.4 nm spectral bandwidth. The wavefront rms error is 30 nm. An interferometric technique for controlling the shapes of the substrates and for adjusting the optical system and detector of the telescope assembly is described in detail.

Fractionated Radiosurgical Treatment of Intracerebral Schwannoma: A Case Report and Literature Review.

Intracranial schwannomas (ICS) unrelated to the cranial nerves are extremely rare; around 70 cases have been reported worldwide. The available literature consists of case reports and small series that present variable characteristics distinguishing these lesions. Brain parenchyma schwannomas are typically benign tumors with currently unknown origins. Diagnosis of intraparenchymal schwannoma is almost never made preoperatively. The management of these tumors usually consists of gross total resection, chemotherapy, and radiotherapy in cases of recurrence. The authors present a case of fractionated Gamma Knife radiosurgical treatment of intracerebral schwannoma following partial microsurgical resection.

Sepsis progression and outcome: a dynamical model.

BACKGROUND: Sepsis (bloodstream infection) is the leading cause of death in non-surgical intensive care units. It is diagnosed in 750,000 US patients per annum, and has high mortality. Current understanding of sepsis is predominately observational and correlational, with only a partial and incomplete understanding of the physiological dynamics underlying the syndrome. There exists a need for dynamical models of sepsis progression, based upon basic physiologic principles, which could eventually guide hourly treatment decisions. RESULTS: We present an initial mathematical model of sepsis, based on metabolic rate theory that links basic vascular and immunological dynamics. The model includes the rate of vascular circulation, a surrogate for the metabolic rate that is mechanistically associated with disease progression. We use the mass-specific rate of blood circulation (SRBC), a correlate of the body mass index, to build a differential equation model of circulation, infection, organ damage, and recovery. This introduces a vascular component into an infectious disease model that describes the interaction between a pathogen and the adaptive immune system. CONCLUSION: The model predicts that deviations from normal SRBC correlate with disease progression and adverse outcome. We compare the predictions with population mortality data from cardiovascular disease and cancer and show that deviations from normal SRBC correlate with higher mortality rates.