RESUMO
There is strong evidence that genetic as well as environmental factors affect the development of periodontitis, and some suggestion that aggressive and chronic forms of the disease share the same genetic predisposition. This study addresses the hypothesis that there are both shared and unique genetic associations in these forms of periodontitis. A sample of 51 patients with aggressive disease, 57 patients with chronic disease, and 100 healthy controls was recruited for this study. Ten functional polymorphisms in 7 candidate genes were genotyped. The results show statistically significant (p Assuntos
Periodontite/genética
, Polimorfismo Genético/genética
, Alelos
, Doença Crônica
, Feminino
, Frequência do Gene
, Predisposição Genética para Doença
, Genótipo
, Humanos
, Interleucina-1/genética
, Interleucina-10/genética
, Interleucina-6/genética
, Masculino
, Regiões Promotoras Genéticas/genética
, Receptores de Calcitriol/genética
, Receptor 4 Toll-Like/genética
, Fator de Necrose Tumoral alfa/genética
