RESUMO
Dillapiole, extracted from Piper aduncum essential oil and its derivatives, has been shown to be a potential alternative to the control of Aedes aegypti, which has become resistant to synthetic insecticides. Methyl ether dillapiole (MED) and temephos (TM) were compared to complement the data on the genotoxicity and developmental changes of Ae. aegypti. Over four generations (G1 -G4 ), third stage larvae were treated with MED at 60, 80 and 100 µg/mL and TM at 0.002, 0.005 and 0.007 µg/mL for 4 h. Adult females were separated to estimate oviposition and hatching rates, and total egg length. Over the four generations, a significant reduction was recorded in oviposition and hatching rates, and in mean egg length (Tukey, P < 0.05), compared with the negative control (NC). Cytological slide preparations were done from adult oocytes and larval neuroblasts. The cumulative effects of genotoxic (bridges, budding and nuclear fragmentation) and mutagenic (micronucleus and chromosomal breakage) damage was observed in the neuroblasts and oocytes of exposed mosquitoes. Developmental changes and damage to the genome of MED-treated Ae. aegypti were greater than those caused by TM. Further studies should focus on understanding the effects of the MED molecule on Ae. aegypti.
Assuntos
Aedes , Inseticidas , Éteres Metílicos , Aedes/genética , Compostos Alílicos , Animais , Dano ao DNA , Dioxóis , Feminino , Inseticidas/farmacologia , Larva , Éteres Metílicos/farmacologia , Mutagênicos/farmacologia , Temefós/farmacologiaRESUMO
We describe eight cases of pediatric patients whose neuroimages performed after seizures revealed abnormalities that were compatible with edema surrounding calcified lesions and which disappeared in subsequent examinations.
Assuntos
Encefalopatias/parasitologia , Edema Encefálico/parasitologia , Calcinose/parasitologia , Epilepsia/parasitologia , Neurocisticercose/diagnóstico , Adolescente , Edema Encefálico/patologia , Criança , Pré-Escolar , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Neurocisticercose/patologia , Remissão Espontânea , Estudos Retrospectivos , Tomografia Computadorizada por Raios XRESUMO
This study was a result of the author's inquiries and reflections, aiming at understanding the meaning that nurses teaching in secondary Nursing courses give to their job. Considering the nature of the problem, this qualitative study used the Grounded Theory as its methodological framework. Data were collected by means of both observation and semi-structured interviews with nine teachers from three schools located in areas of the states of Minas Gerais and São Paulo that offer courses to technicians and/or auxiliary nurses. Data analysis enabled the identification of the "LIVING IN CONSTANT CONFLICT" process as the central theme, especially if we consider that the teachers showed ambiguous feelings and actions regarding their professional practice.