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1.
Pak J Biol Sci ; 25(7): 627-636, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-36098169

RESUMO

<b>Background and Objective:</b> The wheat crop is considered one of the most important crops globally, especially in Egypt. It has great nutritional importance, so it was necessary to increase productivity and any genetic improvement depends on the presence of many genetic differences so that breeders can achieve this. This study aimed to use chemical mutagenic (sodium azide) to obtain the desired genetic differences in two wheat cultivars. <b>Materials and Methods:</b> Two types of bread Sids 12 and Giza 164 were treated with different concentrations of sodium azide (NaN<sub>3</sub>) (1000, 2000, 3000, 4000, 5000 and 6000 ppm). <b>Results:</b> The highest grain/plant 78.91 g was obtained from Sis12 and 62.96 g from Giza 164 compared to the control 42.57 and 40.24 g for Sids 12 and Giza 164, respectively. Also from the results obtained, the relationship of yield was positive and significant with both grain/spike, spikelet's no./spike spikes no./plant and height/plant. On the contrary, it was negative and significant with a 1000-grain weight (-0.433). <b>Conclusion:</b> The two treatments (1000 and 2000 ppm) were the best in the Sids 12, while (1000 and 5000 ppm) were the best treatments in the Giza 164.


Assuntos
Pão , Grão Comestível , Azida Sódica/farmacologia , Triticum/genética
2.
Pak J Biol Sci ; 25(4): 296-303, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-35638523

RESUMO

<b>Background and Objective:</b> It is known that any genetic improvement depends on the presence of many genetic variations so that the plant breeder can choose the desired traits such as the trait of the crop or resistance to some diseases. Different or it can be used for selection, whether for yield, early maturity or other characteristics. This study aimed to use gamma irradiation and the chemical mutagen Dimethyl sulfoxide for the induction of genetic variation in two types of beans. <b>Materials and Methods:</b> The Giza 429 and Misr 1 genotypes were treated with three different concentrations of dimethyl sulfur oxide (1000, 2000 and 3000 ppm) and gamma radiation doses (10, 15 and 20 kr) to perform mutagenesis treatments. <b>Results:</b> In the first and second seasons of the study, all the mutations resulting from the radiological and chemical mutagenic treatments of the two Egyptian bean cultivars, Giza 429 and Misr 1, were highly significant for all treatments in the following traits: Number of branches/plant, plant height, number of pods/plant with the weight of 100 seeds (g) and seed yield/plant (g). <b>Conclusion:</b> The benefit of this research was obtained from plants that outperformed the two cultivars Giza 429 and Misr 1 and are considered among the promising plants that can be used in mixed breeding programs or direct selection for high productivity.


Assuntos
Fabaceae , Vicia faba , Genótipo , Mutagênicos/farmacologia , Fenótipo , Vicia faba/genética
3.
Case Rep Pediatr ; 2013: 307205, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23738178

RESUMO

Ultrasonographic (US) evaluation of spinal anomalies is limited. MRI is increasingly being used in the diagnosis of spinal anomalies. MRI has been able to show clearly the detailed anatomy of this rare case of type II diastematomyelia with triple splitting of the cord.

4.
J Chemother ; 5(5): 289-92, 1993 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-8106900

RESUMO

The effect of sub-MICs of azithromycin, clarithromycin and roxithromycin, as compared to erythromycin, on the production of coagulase, beta-hemolysin, lecithinase and deoxyribonuclease by Staphylococcus aureus was studied. All new macrolides completely inhibited coagulase and beta-hemolysin production and partially inhibited lecithinase and deoxyribonuclease. Such inhibition is not related either to growth inhibition or to inhibition of enzyme activity. Erythromycin, on the other hand, had no effect on coagulase or beta-hemolysin production but slightly suppressed the production of lecithinase and deoxyribonuclease. This inhibitory effect might have clinical significance if it was found to occur in vivo.


Assuntos
Antibacterianos/farmacologia , Staphylococcus aureus/efeitos dos fármacos , Humanos , Macrolídeos , Testes de Sensibilidade Microbiana , Staphylococcus aureus/patogenicidade , Virulência
5.
J Chemother ; 4(5): 276-80, 1992 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-1479416

RESUMO

The effectiveness of six commercially available mouthwashes against common buccal organisms was studied. The minimum inhibitory concentrations (MIC) for two of the studied mouthwashes (Corsodyl and Oraldene) against buccal organisms were determined in Todd Hewitt medium with or without 5% serum. The concentration of the active substance in these two mouthwashes was in excess of the corresponding MIC. When the medium was supplemented with serum, lower MIC values were observed. Kill-time determinations, used at half the concentration of the normal preparation, revealed a rapid lethal effect for all tested mouthwashes. The slowest lethal effect was observed with Fluocaril mouthwash. When mouthwashes were tested in volunteers, an immediate significant fall in salivary bacterial counts was produced by all except Fluocaril. With the latter mouthwash the decrease was significant 2-30 minutes after rinsing. The bacterial levels returned to pre-rinse levels after 30 minutes for Listerine, after 90 minutes for both Oraldene and Mint and after 180 minutes for Corsodyl, Fluocaril and Sansilla mouthwashes. The results indicate that there is a good correlation between in vivo efficacy and in vitro determination of all mouthwash preparations.


Assuntos
Clorexidina/análogos & derivados , Hexitidina/farmacologia , Antissépticos Bucais/farmacologia , Saliva/microbiologia , Candida albicans/efeitos dos fármacos , Clorexidina/farmacologia , Contagem de Colônia Microbiana , Humanos , Testes de Sensibilidade Microbiana , Staphylococcus epidermidis/efeitos dos fármacos , Streptococcus/efeitos dos fármacos
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