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1.
Strahlenther Onkol ; 193(12): 1077-1078, 2017 12.
Artigo em Inglês | MEDLINE | ID: mdl-29080045

RESUMO

Correction to: Strahlenther Onkol 2017 https://doi.org/10.1007/s00066-017-1187-9 Unfortunately, parts of the 'Materials and Methods section' and a sentence in the 'Discussion section' had to be corrected.On page 3, left column, the complete first paragraph was corrected and now reads as follows:Auto-P.

2.
Strahlenther Onkol ; 193(12): 1031-1038, 2017 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-28770294

RESUMO

PURPOSE: This study evaluates the performance and planning efficacy of the Auto-Planning (AP) module in the clinical version of Pinnacle 9.10 (Philips Radiation Oncology Systems, Fitchburg, WI, USA). METHODS AND MATERIALS: Twenty automated intensity-modulated radiotherapy (IMRT) plans were compared with the original manually planned clinical IMRT plans from patients with oropharyngeal cancer. RESULTS: Auto-Planning with IMRT offers similar coverage of the planning target volume as the original manually planned clinical plans, as well as better sparing of the contralateral parotid gland, contralateral submandibular gland, larynx, mandible, and brainstem. The mean dose of the contralateral parotid gland and contralateral submandibular gland could be reduced by 2.5 Gy and 1.7 Gy on average. The number of monitor units was reduced with an average of 143.9 (18%). Hands-on planning time was reduced from 1.5-3 h to less than 1 h. CONCLUSIONS: The Auto-Planning module was able to produce clinically acceptable head and neck IMRT plans with consistent quality.


Assuntos
Órgãos em Risco/efeitos da radiação , Neoplasias Orofaríngeas/patologia , Neoplasias Orofaríngeas/radioterapia , Planejamento da Radioterapia Assistida por Computador/métodos , Radioterapia Conformacional/métodos , Software , Humanos , Tratamentos com Preservação do Órgão , Exposição à Radiação/análise , Dosagem Radioterapêutica , Reprodutibilidade dos Testes , Sensibilidade e Especificidade , Resultado do Tratamento
3.
Med Phys ; 39(6Part19): 3839, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28517105

RESUMO

PURPOSE: To evaluate whether arc therapy (helical Tomotherapy and volumetric arc therapy; VMAT) is superior to step and shoot IMRT regarding sparing of lungs while maintaining adequate planning target volume (PTV) coverage in Hodgkin's lymphoma patients . METHODS: Radiation treatment plans for eleven Hodgkin's lymphoma patients were created employing the following techniques: coplanar and noncoplanar Step & Shoot IMRT, VMAT and Tomotherapy, i.e., for every patient 4 different treatment plans were created. The IMRT and VMAT planning was performed with Pinnacle software (v. 8 and 9, Philips) suitable for delivery with an Elekta linear accelerator, Tomotherapy plans were calculated with Tomotherapy planning software (v. 3.4). Four patients received a single prescription dose of 30 or 36 Gy, and 7 patients received a simultaneous integrated boost (30 Gy/36 Gy). Treatment plans were optimized such that the normal tissue constraints for the lung [volume receiving more than 20 Gy (V20) is less than 30% and mean lung dose (MLD) is less than 14 Gy] were met, even if PTV coverage (V95%=99%) had to be sacrificed. RESULTS: All 4 techniques delivered clinically acceptable treatment plans. Tomotherapy achieved the highest dose homogeneity in the PTV and highest dose coverage of the boost volume (on average 98% versus 96% for the other 3 techniques). Since lung sparing was the first planning objective, all techniques scored equally well for V20 en MLD. CONCLUSIONS: The strength of arc therapy lies in the large number of beamlets entering the patient from a high number of angles. For Hodgkin's lymphoma patients this does not automatically translate into a superior treatment due to the high weight on the lung objectives limiting the number of beamlets allowed to pass through the lung. This means that for Hodgkin's lymphoma arc therapy has no added value for sparing of the lungs.

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